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Persistent B Cell Depletion After Rituximab for Autoimmune and Glomerular Diseases: A Case Series
Introduction: Persistent B cell depletion is a rare complication of rituximab treatment, and its clinical implications are unknown. Methods: This retrospective case series included patients with glomerular and autoimmune diseases who developed persistent
Orhan Efe+9 more
doaj +1 more source
Anti-glomerular basement membrane disease: A clinicomorphological study of 16 cases
Introduction: Antiglomerular basement membrane disease manifests as rapidly progressive glomerulonephritis and alveolar hemorrhage. It encompasses 10–15% of crescentic glomerulonephritis and is associated with poor outcome.
Srinivasrao Vavilapalli+6 more
doaj +1 more source
Clinic manifestations in granulomatosis with polyangiitis [PDF]
Granulomatosis with polyangiitis (GPA), formerly Wegener's granulomatosis (WG), is an uncommon immunologically mediated systemic small-vessel vasculitis that is pathologically characterised by an inflammatory reaction pattern (necrosis, granulomatous ...
De Vincentiis, Marco+7 more
core +1 more source
Membranous nephropathy in a child with crescentic glomerulonephritis: Coincidence or comorbidity?
Rapidly progressive glomerulonephritis (RPGN) is rare syndrome in children, characterized by clinical features of glomerulonephritis and rapid loss of renal function, and is associated with crescentic glomerulonephritis.
Ilknur Girisgen+4 more
doaj +1 more source
. In the present exploratory cross-sectional cohort study, we evaluated whether plasma and urine oxalate concentrations in patients with primary glomerulonephritis depend not only on the glomerular filtration rate but also on the proteinuria level and ...
Natalia Stepanova+3 more
doaj +1 more source
HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal [PDF]
Peritoneal fibrosis is a pathological alteration of the peritoneal membrane occurring in a variety of conditions including peritoneal dialysis (PD), post-surgery adhesions and peritoneal metastases.
Battistelli, Cecilia+14 more
core +1 more source
Fibrillary glomerulonephritis presenting as crescentic glomerulonephritis
Fibrillary glomerulonephritis (FGN) is a rare primary glomerular disease that commonly presents clinically with hypertension, proteinuria, microscopic hematuria, and varying degree of renal insufficiency. Histologically, FGN can present with different patterns of glomerular injury, more commonly mesangioproliferative, membranoproliferative, and ...
J Thakkar+3 more
openaire +2 more sources
Arginase in glomerulonephritis [PDF]
l-Arginine is converted to nitric oxide and citrulline by the enzyme nitric oxide synthase (NOS). Its in vivo inhibition has led to the revelation of a multitude of diverse, often conflicting functions in the inflammatory melee. l-Arginine is also converted to ornithine and urea by the enzyme arginase as a part of the hepatic urea cycle.
openaire +3 more sources
Obstetric and long-term kidney outcomes in renal transplant recipients: a 40 year single-centre study [PDF]
Female renal transplant recipients of childbearing age may ask what the outcomes are for pregnancy and whether pregnancy will affect graft function. We analyzed obstetric and transplant outcomes among renal transplant recipients in our center who have ...
Brennand, Janet E.+6 more
core +1 more source
Post-streptococcal glomerulonephritis is an immune complex-mediated glomerulonephritis as a result of transient dysregulation of alternate complement pathway along with in situ immune complex formation.
Shashank M. Shivanna+4 more
doaj +1 more source