Results 71 to 80 of about 27,996 (190)

A Case of Nephrotic Syndrome, Showing Evidence of Response to Saquinavir

Case Reports in Nephrology, 2015
The treatment of primary nephrotic syndrome such as minimal change nephropathy, membranous nephropathy, and focal segmental glomerulosclerosis nephropathy remains challenging.
Giles Walters, Faisal A. Choudhury, Budhima Nanayakkara   +2 more
doaj   +1 more source

Leveraging extracellular vesicle biology for novel tests and therapeutics for kidney fibrosis

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Extracellular vesicles (EVs) are bilipid membrane‐encased nanoparticles that play critical roles as cell‐to‐cell messengers and waste management mechanisms. EVs cargos can be leveraged as biomarkers to develop minimally invasive tests for kidney fibrosis and guide personalised mechanism‐driven care.
Chin‐Ya Sophie Chiang, Andrew J. Kassianos, Helen Grania Healy, Monica Suet Ying Ng   +3 more
wiley   +1 more source

Primary focal segmental glomerulosclerosis in second trimester pregnancy presenting as rapidly progressive renal failure: diagnostic and therapeutic challenges: a case report

Journal of Medical Case Reports
Background Proteinuria in pregnancy is often attributed to preeclampsia, but primary glomerular diseases such as focal segmental glomerulosclerosis can also present during pregnancy, complicating diagnosis and management.
Adane Petros, Addisu Melkie, Yidnekachew Asrat, Fitsum A. Gemechu, Yewondwossen Tadesse   +4 more
doaj   +1 more source

Effects of intrauterine food restriction and long-term dietary supplementation with L-arginine on age-related changes in renal function and structure of rats [PDF]

, 2005
We have previously demonstrated that restricting intrauterine food by 50% in 3-mo-old rats produced lower nephron numbers and early-onset hypertension, the latter being normalized by L-arginine administration.
Alpers CE, Alves GM, Anderson S, Arcos MI, Barker DJ, Barker DJ, Barker DJ, Boger RH, Brenner BM, Campbell DM, Coimbra TM, Connerty VH, Couser WG, de Carmo Pinho Franco M, Floege J, Floege J, Flores-Mendonza I, Franco Mdo C, Franco Mdo C, Franco Mdo C, Grö, Griffin KA, Johnson RJ, Johnson RJ, Klag MJ, Kliem V, Langley-Evans SC, Lucas SR, Lucas SRR, Lucas SRR, Manning J, Marcantoni C, Melk A, Merlet-Benichou C, Moritz KM, Moritz KM, Ono H, Reckelhoff JF, Reyes AA, Reyes AA, Riser BL, Shih W, Smith HW, Tan D, Tolbert EM, Vaziri ND, Welham SJ, Woods LL, Woods LL, Zatz R   +49 more
core   +1 more source

Development of a Novel UPC (Urine Red Blood Cell Distribution, Proteinuria, and Serum Creatinine) Index to Differentiate Glomerular from Nonglomerular Hematuria

Journal of Clinical Laboratory Analysis, Volume 40, Issue 8, April 2026.
The study developed the UPC index by integrating urine red blood cell distribution (URD), urine protein strip, and serum creatinine to enhance the diagnostic accuracy for distinguishing glomerular from nonglomerular hematuria. The UPC index demonstrated superior performance (AUC 0.857) compared to conventional parameters, showing high sensitivity and ...
Hae In Bang, Sun Min Lee, In Hee Lee, A‐Jin Lee, Chang‐Ho Jeon   +4 more
wiley   +1 more source

Developmental causes of focal segmental glomerulosclerosis

Glomerular Diseases
Background: Focal segmental glomerulosclerosis (FSGS) is a histological pattern of glomerular damage that includes idiopathic conditions as well as genetic and non-genetic forms. Among these various etiologies, different phenotypes within the spectrum of
Luna Shane Klomp, Elena Levtchenko, Rik Westland   +2 more
doaj   +1 more source

Clinical and pathological characteristics of patients with glomerular diseases at a university teaching hospital: 5-year prospective review [PDF]

, 1999
OBJECTIVE. To examine the prevalence of glomerular disease in Hong Kong. DESIGN. Prospective review. SETTING. University teaching hospital, Hong Kong. PATIENTS. All patients who presented with suspected glomerular disease from 1993 through 1997. MAIN
Chan, DTM, Chan, KW, Cheng, IKP
core  

TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy [PDF]

, 2014
Background: Activating mutations in the Transient Receptor Potential channel C6 (TRPC6) cause autosomal dominant focal segmental glomerular sclerosis (FSGS).
Berden, J.H.M. (Jo H.), Coenen, M.J. (Marieke), Hoefsloot, E.H. (Lies), Hofstra, J.M. (Julia), Knoers, N.V.A.M. (Nine), Nijenhuis, T. (Tom), Schijvenaars, M.M.V.A.P. (Mascha), Vlag, J. (Johan) van der, Wetzels, J.F.M. (Jack)   +8 more
core   +1 more source

Rheumatoid Arthritis–Associated Pleural Effusion in an Elderly Female With Multimorbidity: A Case Report and Diagnostic Challenge

Respirology Case Reports, Volume 14, Issue 4, April 2026.
RA Pleural Effusion is a rare but clinically significant extra‐articular manifestation of RA, presenting diagnostic challenges in patients with multimorbidity. This case underscores the importance of considering autoimmune aetiologies in unexplained exudative pleural effusions, particularly when accompanied by joint symptoms or seropositivity.
Aatif Syed, Abdul Kalam Rawther, Pranav Kumar   +2 more
wiley   +1 more source

Graft Embolization versus Nephrectomy in Patients with Graft Intolerance and Infection: A Retrospective Cohort Study

Clinical Transplantation, Volume 40, Issue 4, April 2026.
ABSTRACT Introduction After graft failure, kidney transplant recipients may develop immunological intolerance to the allograft left in situ. In such cases, surgical removal of the allograft is usually performed, but is associated with substantial morbidity and mortality. A less invasive option is percutaneous embolization of the renal artery.
Mattheüs F. Klaassen, Joost Otterspeer, Madelon van Agteren, Sebastiaan Heidt, Diederik Kimenai, Kay J. Pieterman, Robert C. Minnee, Annelies E. de Weerd   +7 more
wiley   +1 more source