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Focal Segmental Glomerulosclerosis [PDF]
New England Journal of Medicine, 2011 Focal segmental glomerulosclerosis accounts for approximately 20% of cases of the nephrotic syndrome in children and 40% of such cases in adults, with an estimated incidence of 7 per 1 million.(1) It is the most common primary glomerular disorder causing end-stage renal disease in the United States, with a prevalence of 4%.(2) The cardinal feature is ...
Frederick Kaskel +2 more
exaly +6 more sources
Pathogenesis of Focal Segmental Glomerulosclerosis [PDF]
Journal of Pathology and Translational Medicine, 2016 Focal segmental glomerulosclerosis (FSGS) is characterized by focal and segmental obliteration of glomerular capillary tufts with increased matrix. FSGS is classified as collapsing, tip, cellular, perihilar and not otherwise specified variants according ...
Beom Jin Lim +3 more
doaj +7 more sources
Focal Segmental Glomerulosclerosis in Waldenström’s Macroglobulinemia [PDF]
Case Reports in Nephrology, 2020 Renal involvement in Waldenström’s macroglobulinemia is a rare manifestation. Although most renal involvement is due to monoclonal immune deposits, pathology can also be unrelated to it.
Akshee Batra +2 more
doaj +4 more sources
Controlling proteinuria in secondary focal segmental glomerulosclerosis with cyclosporine: A case report [PDF]
SAGE Open Medical Case ReportsFocal segmental glomerulosclerosis is a histopathological condition characterized by podocyte injury, which manifests as persistent proteinuria and progressive decline in renal function.
Sohrab Kharabaf +3 more
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Focal Segmental Glomerulosclerosis
Advances in Kidney Disease and HealthFocal segmental glomerular sclerosis (FSGS) is a histological lesion characterized by sclerosis in sections (segmental) of some glomeruli (focal) in association with podocyte injury. Historically, FSGS has often been characterized as a disease, but it is a heterogeneous entity based on etiology, clinical course, and therapeutic approach.
Rout P, Hashmi MF, Baradhi KM.
europepmc +4 more sources
Developmental causes of focal segmental glomerulosclerosis
Glomerular DiseasesBackground: Focal segmental glomerulosclerosis (FSGS) is a histological pattern of glomerular damage that includes idiopathic conditions as well as genetic and non-genetic forms. Among these various etiologies, different phenotypes within the spectrum of
Luna Shane Klomp +2 more
doaj +3 more sources
Journal of Nepal Medical Association, 2023 Introduction: Primary focal segmental glomerulosclerosis is a form of glomerular disease that needs immunosuppressive therapy, which, if untreated, can lead to end-stage renal disease.
Bikash Khatri +3 more
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Focal Segmental Glomerulosclerosis [PDF]
Clinical Journal of the American Society of Nephrology, 2017 Focal segmental glomerulosclerosis (FSGS) is a leading cause of kidney disease worldwide. The presumed etiology of primary FSGS is a plasma factor with responsiveness to immunosuppressive therapy and a risk of recurrence after kidney transplant–important disease characteristics.
Avi Z, Rosenberg, Jeffrey B, Kopp
openaire +2 more sources
Morphometry of podocytes – a single center study of pediatric patients: is there any correlation with proteinuria level? [PDF]
Archives of the Balkan Medical Union, 2019 Introduction. The most common diagnosis after a kidney biopsy in pediatric population is minimal change disease. When the prognosis is not favorable in spite of the minimal change disease diagnosis, there is a clinical suspicion of focal segmental ...
Diana DEREWICZ +4 more
doaj +1 more source
Adult-Onset Genetic Focal Segmental Glomerulosclerosis: A Tale of Two Mutations
Revista Portuguesa de Nefrologia e Hipertensão, 2023 Focal segmental glomerulosclerosis (FSGS) is a kidney histologic lesion that may be caused by multiple aetiologies and pathophysiological mechanisms, with podocyte injury and depletion as the common denominator.
Luís Leite de Sousa +4 more
doaj +1 more source