Results 11 to 20 of about 27,995 (188)

Pilot trial of fk 506 in the management of steroid-resistant nephrotic syndrome [PDF]

open access: yes, 1993
Seven patients with steroid-resistant nephrotic syndrome were treated with FK 506 monotherapy. Four patients were children with focal sclerosing glomerulonephritis (FSGS).
Ellis, D   +9 more
core   +1 more source

A case report: Familial glucocorticoid deficiency associated with familial focal segmental glomerulosclerosis

open access: yesBMC Endocrine Disorders, 2012
Background Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive disorder characterized by isolated glucocorticoid deficiency in the presence of normal plasma renin and aldosterone level.
Ram Nanik, Asghar Ali, Islam Najmul
doaj   +1 more source

Cyclophosphamide in the treatment of focal segmental glomerulosclerosis [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2004
Prednisone is the initial treatment of primary focal segmental glomerulosclerosis. However, when immunosuppressive agents in combination with steroids are used in the treatment of prednisone-dependent and prednisone-resistant patients the remission rate ...
R. Martinelli   +4 more
doaj   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

open access: yes, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim   +1 more
core   +1 more source

APOL1 Risk Alleles Are Associated With More Severe Arteriosclerosis in Renal Resistance Vessels With Aging and Hypertension

open access: yesKidney International Reports, 2016
The increased risk of end-stage kidney disease among hypertensive African Americans is partly related to APOL1 allele variants. The initial glomerulosclerosis of hypertension-associated arterionephrosclerosis consists of focal global glomerulosclerosis ...
Michael D. Hughson   +6 more
doaj   +1 more source

Collapsing glomerulopathy in sickle cell disease: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Sickle cell disease has been associated with many renal structural and functional abnormalities. Collapsing glomerulopathy or the collapsing variant of focal segmental glomerulosclerosis is a rare clinicopathologic entity in patients with ...
Sealy Peter L   +2 more
doaj   +1 more source

Soluble urokinase plasminogen activator receptor (suPAR) and glomerular disease in children: a narrative review

open access: yesEgyptian Pediatric Association Gazette, 2022
Background Focal segmental glomerulosclerosis (FSGS) is a chronic glomerular disease that responds poorly to treatment, with a large proportion of patients progressing to end-stage renal disease in spite of initial aggressive treatment.
Phuong Anh Le Thy   +3 more
doaj   +1 more source

suPAR and Team Nephrology [PDF]

open access: yes, 2014
Primary focal segmental glomerulosclerosis (FSGS) accounts for nearly 10 % of patients who require renal replacement therapy. Elevated circulating levels of soluble urokinase receptor (suPAR) have been identified as a biomarker to discriminate primary ...
Howard Trachtman
core   +2 more sources

Gorham-Stout Syndrome with Focal Segmental Glomerulosclerosis: A Case Report [PDF]

open access: yesChildhood Kidney Diseases, 2020
Gorham-Stout syndrome is a rare bone disorder characterized by progressive massive osteolysis and proliferation of vascular and lymphatic vessels. A 15-year-old boy was initially diagnosed with Gorham-Stout at the age of 8 years based on clinical and ...
Ji Hyun Kim   +10 more
doaj   +1 more source

Treatment of steroid-resistant pediatric nephrotic syndrome [PDF]

open access: yes, 2011
Children who suffer from steroid-resistant nephrotic syndrome (SRNS) require aggressive treatment to achieve remission. When intravenous high-dose methylprednisolone fails, calcineurin inhibitors, such as cyclosporine and tacrolimus, are used as the ...
Hee Gyung Kang
core   +1 more source

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