Results 31 to 40 of about 21,067 (213)

APOL1 Risk Alleles Are Associated With More Severe Arteriosclerosis in Renal Resistance Vessels With Aging and Hypertension

open access: yesKidney International Reports, 2016
The increased risk of end-stage kidney disease among hypertensive African Americans is partly related to APOL1 allele variants. The initial glomerulosclerosis of hypertension-associated arterionephrosclerosis consists of focal global glomerulosclerosis ...
Michael D. Hughson   +6 more
doaj   +1 more source

The Pathogenesis of Focal Segmental Glomerulosclerosis [PDF]

open access: yesAdvances in Chronic Kidney Disease, 2014
Focal segmental glomerulosclerosis (FSGS) is a histologic pattern of injury on kidney biopsy that can arise from a diverse range of causes and mechanisms. Although primary and secondary forms are described based on the underlying cause, there are many common factors that underlie the development of this segmental injury.
J Ashley, Jefferson, Stuart J, Shankland
openaire   +2 more sources

Collapsing glomerulopathy in sickle cell disease: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Sickle cell disease has been associated with many renal structural and functional abnormalities. Collapsing glomerulopathy or the collapsing variant of focal segmental glomerulosclerosis is a rare clinicopathologic entity in patients with ...
Sealy Peter L   +2 more
doaj   +1 more source

Focal segmental glomerulosclerosis in adults [PDF]

open access: yesNephrology Dialysis Transplantation, 2003
Abstract The lesion of focal segmental glomerulosclerosis (FSGS) presents even greater problems of definition, interpretation and treatment in adults than it does in children, to the point where the specificity and utility of the appearance can even be questioned.
openaire   +2 more sources

Soluble urokinase plasminogen activator receptor (suPAR) and glomerular disease in children: a narrative review

open access: yesEgyptian Pediatric Association Gazette, 2022
Background Focal segmental glomerulosclerosis (FSGS) is a chronic glomerular disease that responds poorly to treatment, with a large proportion of patients progressing to end-stage renal disease in spite of initial aggressive treatment.
Phuong Anh Le Thy   +3 more
doaj   +1 more source

Primary focal segmental glomerulosclerosis

open access: yes, 2018
The proportion of cases of primary focal segmental glomerulosclerosis responsive to treatment with corticosteroids is variable and depends on histological type, patient age and duration, and dose of steroid treatment, but overall complete remission rate ...
Alain Meyrier, Patrick Niaudet
core   +2 more sources

Idiopathic focal segmental glomerulosclerosis

open access: yesIndian Pediatrics, 2009
This study was conducted to determine the prognostic value of some clinical, laboratory, histopathologic and therapeutic factors in 62 children with focal segmental glomerulosclerosis. There were no significant differences between the factors studied, except for severe interstitial fibrosis, which was more frequent in patients with chronic kidney ...
Mitra, Naseri   +3 more
openaire   +2 more sources

Mechanisms of Scarring in Focal Segmental Glomerulosclerosis

open access: yesKidney Diseases, 2021
Background: Focal segmental glomerulosclerosis (FSGS) is a histologic pattern characterized by focal glomerular scarring, which often progresses to systemic and diffuse glomerulosclerosis.
Ke Sun, Qionghong Xie, Chuan-Ming Hao
doaj   +1 more source

Mucin-1 Gene Mutation and the Kidney: The Link between Autosomal Dominant Tubulointerstitial Kidney Disease and Focal and Segmental Glomerulosclerosis

open access: yesCase Reports in Nephrology, 2018
Glomerular diseases are one of the most frequent causes of chronic kidney disease, focal and segmental glomerulosclerosis being one of the commonest glomerulopathies.
H. Trimarchi   +8 more
doaj   +1 more source

The Spectrum of Biopsy‐Proven Renal Diseases in Chinese Elderly Patients and Its Temporal Shift Over 20 Years: A Retrospective Cohort Study

open access: yesAGING MEDICINE, EarlyView.
This 20‐year retrospective study reveals a significant increase in renal biopsy utilization and a pivotal shift in biopsy‐proven renal disease among Chinese elderly patients. Secondary glomerular nephropathy (particularly diabetic nephropathy and hypertensive nephropathy) has surpassed primary glomerular nephropathy as the leading biopsy‐proven ...
Shasha Han   +4 more
wiley   +1 more source

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