Results 1 to 10 of about 56,062 (233)
Hypertension and age‐related focal global glomerulosclerosis are associated with biomarkers for cellular senescence [PDF]
Physiological ReportsArterionephrosclerosis is characterized by focal global glomerulosclerosis (FGGS), which is a constant feature of aging and hypertension.
Michael D. Hughson +4 more
doaj +2 more sources
Diabetic Glomerulosclerosis [PDF]
Medical Journal of Australia, 1966 Why should the mesangial cells be irritated? We recently observed in some diabetics black deposits beneath and on both sides of the basement membrane. These appear quite similar to deposits seen in and around the basement membrane in glomerulonephritis ...
Bloodworth, J. M. B., Jr.
core +6 more sources
Temporal glomerular gene expression dynamics during disease progression in a mouse model of hypertension‐accelerated diabetic kidney disease [PDF]
Animal Models and Experimental MedicineBackground The current understanding of diabetic kidney disease (DKD) has significant gaps regarding the underlying pathogenesis. In this study, we aimed to characterize the temporal progression of DKD using a state‐of‐the‐art mouse model of hypertension‐
Adam B. Marstrand‐Jørgensen +8 more
doaj +2 more sources
Renal pathology associated with visceral gout in ducks [PDF]
Journal of Veterinary and Animal Sciences, 2022 Visceral gout is a metabolic disease of birds characterized by deposition of urate crystals in visceral organs. Though occurrence of visceral gout is common in chicken, reports from ducks and descriptions of its renal pathology are scarce.
A. M. Anagha +5 more
doaj +1 more source
Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]
, 2013 Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Amann, Kerstin +13 more
core +16 more sources
Glomerular Endothelial Cell Crosstalk With Podocytes in Diabetic Kidney Disease
Frontiers in Medicine, 2021 Diabetes is the main cause of renal failure worldwide. Complications of the kidney micro-and macro-circulation are common in diabetic patients, leading to proteinuria and can progress to end-stage renal disease.
Nassim Mahtal +2 more
doaj +1 more source
The Effects of TRPC6 Knockout in Animal Models of Kidney Disease
Biomolecules, 2022 Diseases that induce a loss of renal function affect a substantial portion of the world’s population and can range from a slight decline in the glomerular filtration rate or microalbuminuria to complete kidney failure.
Stuart E. Dryer, Eun Young Kim
doaj +1 more source
A Case of Focal Segmental Glomerulosclerosis in Turner Syndrome [PDF]
Kosin Medical Journal, 2015 Turner syndrome is usually accompanied with various anomalies. Congenital urological and renal abnormalities are often associated with this syndrome. The occurrence of glomerulonephritis is uncommon.
A Rum Han +5 more
doaj +1 more source
Srpski Arhiv za Celokupno Lekarstvo, 2020 Podocytopathies include a wide spectrum of primary or secondary glomerular diseases that are the consequence of the podocyte injuries. The damage of podocytes can occur due to congenital or acquired disorders of podocyte transcriptional regulators ...
Peco-Antić Amira, Mulić Bilsana
doaj +1 more source
Resistive index and kidney biopsy: what correlation in chronic kidney disease?. [PDF]
Batna Journal of Medical Sciences, 2023 Introduction. Chronic kidney disease (CKD) represents a global public health problem. Its progression to the end stage is based on the existence and severity of histological lesions, especially interstitial fibrosis and vascular lesions, and exposes a
Djahid BENDJEDDOU +6 more
doaj +1 more source