Results 41 to 50 of about 56,062 (233)

A study on variants of focal segmental glomerulosclerosis and their relationship with various biochemical and demographic parameters in kidney biopsies; a single center study [PDF]

Journal of Nephropharmacology, 2019
Introduction: Focal segmental glomerulosclerosis (FSGS) is one of the most common glomerular diseases leading to end-stage renal failure. According to Columbia classification, there are five histologic variants for FSGS.
Fahimeh Fatehi, Seyed Mohsen Hosaini, Hamid Nasri   +2 more
doaj   +1 more source

Cardiorenal Involvement in Metabolic Syndrome Induced by Cola Drinking in Rats: Proinflammatory Cytokines and Impaired Antioxidative Protection [PDF]

, 2016
We report experimental evidence confirming renal histopathology, proinflammatory mediators, and oxidative metabolism induced by cola drinking. Male Wistar rats drank ad libitum regular cola (C, = 12) or tap water (W, = 12). Measures.
Ambrosio, Giuseppe, Azzato, Francisco, Cao, Gabriel Fernando, Gómez Llambí de Oromí, Hernán Jorge, Milei, Jose, Muller, Maria Angelica, Otero-Losada, Matilde Estela, Ottaviano, Graciela Mabel   +7 more
core   +1 more source

Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice [PDF]

, 2019
SH3 domain-binding protein 2 (SH3BP2) is an adaptor protein that is predominantly expressed in immune cells, and it regulates intracellular signaling. We had previously reported that a gain-of-function mutation in SH3BP2 exacerbates inflammation and bone
Iseki, Masanori, Ishihara, Katsuhiko, Kashihara, Naoki, Kawahara, Kyoko, Morita, Yoshitaka, Mukai, Tomoyuki, Nagasu, Akiko, Nagasu, Hajime, Tsuji, Shoko, Ueki, Yasuyoshi   +9 more
core   +1 more source

Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy [PDF]

, 2014
Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is
Haylor, John, Shrestha, Badri Man
core   +6 more sources

PPAR-α Insufficiency Enhances Doxorubicin-Induced Nephropathy in PPAR-α Knockout Mice and a Murine Podocyte Cell Line

Cells
Peroxisome proliferator-activated receptor-alpha (PPAR-α) and its exogenous activators (fibrates) promote autophagy. However, whether the deleterious effects of PPAR-α deficiency on doxorubicin (DOX)-induced podocytopathy are associated with reduced ...
Kohei Matsuta, Kazuko Kamiyama, Toru Imamoto, Izumi Takeda, Shinya Masunaga, Mamiko Kobayashi, Naoki Takahashi, Kenji Kasuno, Masanori Hara, Masayuki Iwano, Tadashi Toyama, Hideki Kimura   +11 more
doaj   +1 more source

IgA Nephropathy Associated with IgA Vasculitis Coexisting with Focal Segmental Glomerulosclerosis Tip Variant

Journal of Renal and Hepatic Disorders, 2023
IgA vasculitis (IgAV), previously known as Henoch–Schönlein purpura, is a form of small vessel vasculitis that affects the skin, joints, intestines, and kidneys.
Zitlali Guadalupe Paulín Zepeda, Karla Daniela Salgado Guizar, Vianey Guadalupe Tellez Bolaños, Louis Fernando Robles Fernandes, María Inés Gil Arredondo   +4 more
doaj   +1 more source

Experimental rat models of chronic allograft nephropathy: a review [PDF]

, 2014
Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
core   +2 more sources

Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis [PDF]

, 2012
Current macrophage phenotype classifications are based on distinct in vitro culture conditions that do not adequately mirror complex tissue environments.
Allam R, Allen JE, Anders HJ, Anders HJ, Anders HJ, Anders HJ, Anders HJ, Anders HJ, Andersson-Sjoland A, Arnold L, Atabai K, Barczyk K, Barron L, Bedke J, Belperio JA, Belperio JA, Benoit M, Bertalan R, Blease K, Bonventre JV, Bonventre JV, Broekema M, Burdick MD, Cao Q, Cardenas H, Castano AP, Chorro L, Chow A, Cowin AJ, Crispe IN, Dehmel S, Drake TA, Duffield JS, Duffield JS, Ehninger A, Eis V, El Chartouni C, Fallowfield JA, Fang Y, Fichtner-Feigl S, Filardy AA, Forbes SJ, Galli SJ, Ghielli M, Gordon S, Grgic I, Gurtner GC, Hans-Joachim Anders, Harty MW, Haudek SB, Hayasaki T, Hayashidani S, Hayashidani S, Herbert DR, Huang XR, Ide M, Ikezumi Y, Ikezumi Y, Imamura M, Iredale JP, Ishida Y, Ishii M, Jiang D, Jiang W, John R, Jose MD, Kapsenberg ML, Karlmark KR, Kawai T, King IL, Kisseleva T, Kitagawa K, Kluth DC, Kono H, Krausgruber T, Kulkarni O, Kulkarni O, Lassen S, Lech M, Lech M, Lee S, Lee SB, Leibovich SJ, Leonardo CC, Leor J, Lin SL, Liu G, Lu TT, Lucas M, Lucas T, MacDonald TT, Mantovani A, Marc Weidenbusch, Marra F, Martin P, Martinez FO, Matzinger P, Matzinger P, Medzhitov R, Meisel SR, Messier-Solek C, Mildner A, Mirza R, Mitchell C, Mori L, Mori R, Morimoto H, Mosser DM, Mowat AM, Nahrendorf M, Negishi H, Nelson PJ, Niedermeier M, Ninichuk V, Ninichuk V, Ninichuk V, Nishida M, Occleston NL, Okuma T, Oliphant CJ, Otogawa K, Patole PS, Patole PS, Patole PS, Pawar RD, Pawar RD, Pesce JT, Pilling D, Popov Y, Quan TE, Raghavendra V, Raivich G, Rakoff-Nahoum S, Rapalino O, Rast JP, Ren F, Rock KL, Rock KL, Ryu M, Sakai N, Sathe P, Satoh T, Savill J, Savill J, Schmidt M, Scholten D, Segawa M, Seki E, Semple JW, Shechter R, Shi J, Sindrilaru A, Singer AJ, Smith PD, Sorokin L, Spataro L, Stefater, Swaminathan S, Takeuchi O, Thomas JA, Tian DS, Tian DS, Tokuda A, van Amerongen MJ, van Amerongen MJ, Vielhauer V, Vielhauer V, Wada T, Wada T, Wang Y, Wang Y, Wang Y, Welzen-Coppens JM, Xing Z, Yang L, Yang L, Yang Z, Zeisberg M, Zeisberg M, Zeisberg M, Zheng D, Ziv Y   +181 more
core   +3 more sources

Early Renoprotective Effect of Ruxolitinib in a Rat Model of Diabetic Nephropathy

Pharmaceuticals, 2021
Diabetic kidney disease (DKD) is still one of the unresolved major complications of diabetes mellitus, which leads ultimately to end-stage renal disease in both type 1 and type 2 diabetes patients.
Mohamed M. El-Kady, Reham A. Naggar, Maha Guimei, Iman M. Talaat, Olfat G. Shaker, Maha Saber-Ayad   +5 more
doaj   +1 more source

Dietary interventions to contrast the onset and progression of diabetic nephropathy. a critical survey of new data [PDF]

, 2017
This article is a critical overview of recent contributions on the dietary corrections and the foods that have been claimed to delay or hinder the onset of diabetic nephropathy (DN) and its progression to end-stage renal disease.
Iacobini, Carla, Menini, Stefano, Pesce, Carlo, Pugliese, Giuseppe   +3 more
core   +1 more source