Results 51 to 60 of about 56,062 (233)

The role of zinc in renal pathological changes in diabetic status [PDF]

, 2015
Diabetes mellitus (DM) was the 8th leading cause of death in 2011, resulting in 1.4 million deaths worldwide. One of the complications of DM is chronic kidney disease, which accounts for nearly 44% of all new cases of kidney failure in the US in 2011 ...
Fernando, Julie, Zhou, Shaobo
core   +1 more source

Clinical, histological, and serological predictors of renal function loss in lupus nephritis.

Arthritis Care &Research, Accepted Article.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M Guthridge, Carla Guthridge, Peter Izmirly, Jill P Buyon, H.Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership RA/SLE Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

Association of Ancillary Pathology Findings in Non-neoplastic Renal Parenchyma and Renal Outcomes of Robotic-Assisted Partial Nephrectomy

Frontiers in Surgery, 2021
Background: To evaluate robotic-assisted partial nephrectomy (RAPN) renal outcomes associated with ancillary pathology findings in non-neoplastic renal parenchymal tissue.Methods: Tissue samples from 378 RAPNs were analyzed for glomerular disease (GD ...
Laura E. Geldmaker, Amanda E. Kahn, Kevin A. Parikh, Ivan E. Porter, Daniela A. Haehn, Essa M. Bajalia, Qihui Zhai, Colleen T. Ball, David D. Thiel   +8 more
doaj   +1 more source

Questions about Chemokine and Chemokine Receptor Antagonism in Renal Inflammation [PDF]

, 2010
Chemokines remain attractive therapeutic targets for modulating inflammatory diseases in all areas of medicine including acute and chronic kidney disease.
Anders, Hans-Joachim, Sayyed, Sufyan Ali, Vielhauer, Volker   +2 more
core   +1 more source

GloPath: An Entity‐Centric Foundation Model for Glomerular Lesion Assessment and Clinicopathological Insights

Advanced Science, EarlyView.
An entity‐centric foundation model, GloPath, is introduced for comprehensive glomerular lesion assessment from routine renal biopsy images. Trained on over one million glomeruli, the framework enables robust lesion recognition, grading, and cross modality diag nosis, while uncovering large‐scale clinicopathological associations.
Qiming He, Jing Li, Tian Guan, Yifei Ma, Zimo Zhao, Yanxia Wang, Hongjing Chen, Yingming Xu, Shuang Ge, Yexing Zhang, Yizhi Wang, Xinrui Chen, Lianghui Zhu, Yiqing Liu, Qingxia Hou, Shuyan Zhao, Xiaoqin Wang, Lili Ma, Peizhen Hu, Qiang Huang, Zihan Wang, Zhiyuan Shen, Junru Cheng, Siqi Zeng, Jiurun Chen, Zhen Song, Chao He, Zhe Wang, Yonghong He   +28 more
wiley   +1 more source

Integrative Analyses Identify a cGAS‐STING Pathway‐Driven Signature With Context‐Dependent Roles in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang, Ming‐Ju Amy Lyu, Ze Hong, Jing Sun, Lan Guo, Jiameng Hu, Munire Maimaiti, Chenhui Li, Jinyi Song, Xiang Zhang, Huansha Yu, Chen Wang, Xuan Wang, Haiyang Hu   +13 more
wiley   +1 more source

Prevalence of pulmonary thromboembolism in nephrotic syndrome patients: A systematic review and meta-analysis

Journal of Family Medicine and Primary Care, 2020
This study was aimed to assess the prevalence of pulmonary thromboembolism in patients with nephrotic syndrome. An electronic search was conducted through nine electronic databases for selection of relevant articles reporting the prevalence of pulmonary ...
Abdullah Nasser Leslom, Ziyad Mohammed Saeed Alrawiah, Ahmed Mohammed Ahmed Al-Asmari, Moneer Dhafer Ali Alqashaneen, Abdulaziz Oudah Tami Alahmari, Hamuod Oudah Bin Tami Al-Ahmari   +5 more
doaj   +1 more source

Prognostic value of chronicity grading on renal outcomes in patients with IgA nephropathy

Frontiers in Medicine, 2022
Many studies have shown that chronic changes are strong predictors of renal outcomes in various kidney diseases, including IgA nephropathy. The Mayo Clinic/Renal Pathology Society suggested a glomerulonephritis reporting system with a proposal for ...
Donghyuk Kang, Tae Hyun Ban, Ho Jun Chin, Hajeong Lee, Se Won Oh, Cheol Whee Park, Chul Woo Yang, Bum Soon Choi   +7 more
doaj   +1 more source

KAJIAN EKSPRESI TGF-ββββ1, MMP-9, KOLAGEN TIPE-1, KOLAGEN TIPE-IV, GLOMERULOSKLEROSIS, INTERSTISIAL FIBROSIS, ALBUMINURIA PADA KEJADIAN NEFROTOKSIK DOXORUBICIN DAN NEFROPROTEKTIF PENTOXIFYLLIN DENGAN HEWAN COBA MENCIT GALUR SWISS JANTAN [PDF]

, 2010
Pemakaian Doxorubicin (DXR) dalam pengobatan kanker semakin meningkat, dengan meningkatnya morbiditas kanker. Efek nefrotoksik dari DXR masih menjadi masalah.
Purwanto, Bambang
core   +1 more source

Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models

Advanced Science, EarlyView.
Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler, Tim Lange, Sophia‐Marie Bach, Soeren S. Lienkamp, Nicole Endlich   +4 more
wiley   +1 more source