Results 1 to 10 of about 27,996 (190)

Primary Focal Segmental Glomerulosclerosis among Patients with Glomerular Disease Undergoing Kidney Biopsy in a Tertiary Care Centre: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2023
Introduction: Primary focal segmental glomerulosclerosis is a form of glomerular disease that needs immunosuppressive therapy, which, if untreated, can lead to end-stage renal disease.
Bikash Khatri, Anil Baral, Suresh Maharjan, Bijay Khatri   +3 more
doaj   +1 more source

Morphometry of podocytes – a single center study of pediatric patients: is there any correlation with proteinuria level? [PDF]

Archives of the Balkan Medical Union, 2019
Introduction. The most common diagnosis after a kidney biopsy in pediatric population is minimal change disease. When the prognosis is not favorable in spite of the minimal change disease diagnosis, there is a clinical suspicion of focal segmental ...
Diana DEREWICZ, Roxana TARAS, Cosmin FLORESCU, Mihaela BALGRADEAN, Maria SAJIN   +4 more
doaj   +1 more source

Adult-Onset Genetic Focal Segmental Glomerulosclerosis: A Tale of Two Mutations

Revista Portuguesa de Nefrologia e Hipertensão, 2023
Focal segmental glomerulosclerosis (FSGS) is a kidney histologic lesion that may be caused by multiple aetiologies and pathophysiological mechanisms, with podocyte injury and depletion as the common denominator.
Luís Leite de Sousa, Gonçalo Pimenta, Rita Veríssimo, Rita Theias, Tiago Carvalho   +4 more
doaj   +1 more source

Pathogenesis of Focal Segmental Glomerulosclerosis [PDF]

Journal of Pathology and Translational Medicine, 2016
Focal segmental glomerulosclerosis (FSGS) is characterized by focal and segmental obliteration of glomerular capillary tufts with increased matrix. FSGS is classified as collapsing, tip, cellular, perihilar and not otherwise specified variants according ...
Beom Jin Lim, Jae Won Yang, Woo Sung Do, Agnes B. Fogo   +3 more
doaj   +1 more source

Autoimmunity in Focal Segmental Glomerulosclerosis: A Long-Standing Yet Elusive Association

Frontiers in Medicine, 2020
Focal segmental glomerulosclerosis (FSGS) is a histological term that describes a pathologic renal entity affecting both adults and children, with a wide array of possible underlying etiologies.
Manuel Alfredo Podestà, Claudio Ponticelli   +1 more
doaj   +1 more source

Loss of phosphatidylserine flippase β-subunit Tmem30a in podocytes leads to albuminuria and glomerulosclerosis

Disease Models & Mechanisms, 2021
The asymmetric distribution of phosphatidylserine (PS) in the cytoplasmic leaflet of eukaryotic cell plasma membranes is regulated by a group of P4-ATPases (named PS flippases) and the β-subunit TMEM30A.
Wenjing Liu, Lei Peng, Wanli Tian, Yi Li, Ping Zhang, Kuanxiang Sun, Yeming Yang, Xiao Li, Guisen Li, Xianjun Zhu   +9 more
doaj   +1 more source

Focal segmental glomerulosclerosis in which urinary protein improved after surgical treatment for acromegaly: a case report

Journal of Medical Case Reports, 2019
Background Focal segmental glomerulosclerosis is characterized by partial (segmental) sclerotic lesions in some glomeruli (focal). Primary focal segmental glomerulosclerosis is generally considered resistant to steroid therapy.
Arina Yamasaki, Daisuke Bito, Erina Eto, Keiichiro Matsumoto, Megumi Nakamura, Junji Miyazaki, Kenichi Matsumoto, Masanori Masuda, Daisuke Mori, Toru Yoshimura   +9 more
doaj   +1 more source

A Case of Focal Segmental Glomerulosclerosis in Turner Syndrome [PDF]

Kosin Medical Journal, 2015
Turner syndrome is usually accompanied with various anomalies. Congenital urological and renal abnormalities are often associated with this syndrome. The occurrence of glomerulonephritis is uncommon.
A Rum Han, Young Ki Lee, Hyun Yon Jung, Jae Hyun Park, Jung-Woo Noh, Eun Suk Nam   +5 more
doaj   +1 more source

Eluate derived by extracorporal antibody-based immunoadsorption elevates the cytosolic Ca2+ concentration in podocytes via B-2 kinin receptors [PDF]

, 2002
Background/Aim: Patients with idiopathic focal segmental glomerulosclerosis (FSGS) often develop a recurrence of the disease after kidney transplantation.
Fink, E., Fischer, K. G., Henger, A., Huber, T. B., Pavenstadt, H., Rump, L. C., Schwertfeger, E.   +6 more
core   +1 more source

Pilot trial of fk 506 in the management of steroid-resistant nephrotic syndrome [PDF]

, 1993
Seven patients with steroid-resistant nephrotic syndrome were treated with FK 506 monotherapy. Four patients were children with focal sclerosing glomerulonephritis (FSGS).
Ellis, D, Igdal, H, McCalley, J, Shapiro, R, Shapiro, R, Starzl, TE, Starzl, TE, Starzl, TE, Tzakis, A, Tzakis, A   +9 more
core   +1 more source