Results 41 to 50 of about 388,681 (160)

Mechanisms of Scarring in Focal Segmental Glomerulosclerosis

open access: yesKidney Diseases, 2021
Background: Focal segmental glomerulosclerosis (FSGS) is a histologic pattern characterized by focal glomerular scarring, which often progresses to systemic and diffuse glomerulosclerosis.
Ke Sun, Qionghong Xie, Chuan-Ming Hao
doaj   +1 more source

T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease

open access: yesAdvanced Science, EarlyView.
This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li   +11 more
wiley   +1 more source

Recurrent Focal Segmental Glomerulosclerosis after Renal Transplantation

open access: yes, 1991
In a young adult male with chronic renal failure from focal segmental glomerulosclerosis, massive proteinuria appeared within two weeks after transplantation.
M. Minz   +4 more
core   +1 more source

Mucin-1 Gene Mutation and the Kidney: The Link between Autosomal Dominant Tubulointerstitial Kidney Disease and Focal and Segmental Glomerulosclerosis

open access: yesCase Reports in Nephrology, 2018
Glomerular diseases are one of the most frequent causes of chronic kidney disease, focal and segmental glomerulosclerosis being one of the commonest glomerulopathies.
H. Trimarchi   +8 more
doaj   +1 more source

Baseline podocyte‐associated state and persistent cell–matrix transcriptional programs are associated with BALB/c substrain differences in adriamycin nephropathy

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Two closely related BALB/c substrains exhibit different early responses to adriamycin (ADR)‐induced nephropathy. BALB/cByJcl mice showed lower baseline WT1‐positive nuclei counts and NPHS1 immunoreactivity than BALB/cAJcl mice, together with extracellular matrix and integrin programs that were enriched at baseline and persisted at Day 5.
Ryuya Nakagawa   +5 more
wiley   +1 more source

Primary Focal Segmental Glomerulosclerosis: Why Are Pieces of This Puzzle Still Missing? [PDF]

open access: yes, 2015
Focal segmental glomerulosclerosis (FSGS) can be classified as primary or secondary. Moreover, many causes of primary FSGS have been identified in recent years. In this regard, genetic circulating permeability factors and the abnormal podocyte expression
Hernán Trimarchi
core  

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

POEMS syndrome, calciphylaxis and focal segmental glomerulosclerosis - VEGF as a possible link. [PDF]

open access: yes, 2014
Polyneuropathy organomegaly endocrinopathy M-protein skin changes (POEMS) syndrome is a rare cause of polyneuropathy. Calciphylaxis, a severe disease leading to necrotic ulcers of the skin, is associated with POEMS syndrome and also with renal disease ...
Heck, Dorothee;Mergen, Miriam;Ganner, Athina;Pelisek, Jaroslav;Mader, Irina;Weiller, Cornelius;Niesen, Wolf-Dirk
core   +2 more sources

Progression of albuminuria and podocyte injury in focal segmental glomerulosclerosis inhibited by enhanced glycosphingolipid GM3 via valproic acid

open access: yesScientific Reports, 2023
Focal segmental glomerulosclerosis, characterized by decreased numbers of podocytes in glomeruli, is a common cause of refractory nephrotic syndrome. Recently, we showed that enhanced glycosphingolipid GM3 expression after administration of valproic acid,
Nagako Kawashima   +4 more
doaj   +1 more source

Focal Segmental Glomerulosclerosis with Sjogren Syndrome: A Case Report

open access: yesTurkish Journal of Internal Medicine, 2021
Sjogren's syndrome (SjS) is a chronic, slow-progressing, autoimmune and lymphoproliferative disease. The main symptoms of the syndrome are xerostomia and keratoconjuctivitis sicca as a result of chronic inflammatory infiltration of the salivary and ...
Mehmet Sezen   +7 more
doaj   +1 more source

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