Results 21 to 30 of about 388,681 (160)

Collapsing focal segmental glomerulosclerosis: Increasing the awareness [PDF]

Journal of Nephropathology, 2012
Collapsing focal segmental glomerulosclerosis (cFSGS), also known as collapsing glomerulopathy (CG) is of considerable interest for a variety of reasons.
Muhammed Mubarak
doaj   +3 more sources

Focal and segmental glomerulosclerosis.

NLM images of a patient with focal and segmental glomerulosclerosis were acquired every 4 μm in depth. Images spaced 12 μm apart in depth show a segmental obliteration of the glomerular tuft with sclerosis (blue arrow), adhesions and obliteration of the ...
Milan Rosen (18165456), Timothy D. Weber (18165459), James G. Fujimoto (14904756), Tadayuki Yoshitake (18165453), Lucas C. Cahill (18165450), Seymour Rosen (3092964)   +5 more
core   +2 more sources

Focal Segmental Glomerulosclerosis [PDF]

Clinical Journal of the American Society of Nephrology, 2017
Focal segmental glomerulosclerosis (FSGS) is a leading cause of kidney disease worldwide. The presumed etiology of primary FSGS is a plasma factor with responsiveness to immunosuppressive therapy and a risk of recurrence after kidney transplant–important disease characteristics.
Avi Z, Rosenberg, Jeffrey B, Kopp
openaire   +2 more sources

Genetics of focal segmental glomerulosclerosis [PDF]

Pediatric Nephrology, 2007
AbstractThe recent advances in understanding the pathophysiology of focal segmental glomerulosclerosis (FSGS) and molecular function of glomerular filtration barrier come directly from genetic linkage and positional cloning studies. The exact role and function of the newly discovered genes and proteins are being investigated by in vitro and in vivo ...
Woroniecki, Robert P., Kopp, Jeffrey B.
openaire   +2 more sources

NPHS2variation in focal and segmental glomerulosclerosis [PDF]

BMC Nephrology, 2008
Abstract Background Focal and segmental glomerulosclerosis (FSGS) is the most common histologic pattern of renal injury seen in adults with idiopathic proteinuria. Homozygous or compound heterozygous mutations in the podocin gene NPHS2 are found in 10–30% of pediatric cases of steroid resistant nephrosis and/or FSGS.
Tonna, Stephen, Needham, Alexander, Polu, Krishna, Uscinski, Andrea, Appel, Gerald B., Falk, Ronald, Katz, Avi, Al-Waheeb, Salah, Kaplan, Bernard, Jerums, George, Savige, Judy, Harmon, Jennifer, Zhang, Kang, Curhan, Gary, Pollak, Martin   +14 more
openaire   +5 more sources

Eluate derived by extracorporal antibody-based immunoadsorption elevates the cytosolic Ca2+ concentration in podocytes via B-2 kinin receptors [PDF]

, 2002
Background/Aim: Patients with idiopathic focal segmental glomerulosclerosis (FSGS) often develop a recurrence of the disease after kidney transplantation.
Pavenstadt, H., Rump, L. C., Fischer, Karl-Georg, Pavenstädt, Hermann, Schwertfeger, E., Henger, Anna, Fischer, K. G., Rump, Lars Christian, Fink, E., Huber, Tobias B., Schwertfeger, Eckhard, Henger, A., Huber, T. B., Fink, Edwin   +13 more
core   +1 more source

A case of minimal change nephrotic syndrome with immunoglobulin A nephropathy transitioned to focal segmental glomerulosclerosis [PDF]

, 2012
A 50-year-old woman with a 1-month history of lower extremity edema and a 5 kg weight increase was admitted to our hospital with suspected nephrotic syndrome in October 1999.
Miyazaki, Masanobu, Takashi Taguchi, Mineaki Kitamura, Misaki Hirose, Obata, Yoko, Uramatsu, Tadashi, Kitamura, Mineaki, Taguchi, Takashi, Nishino, Tomoya, Hirose, Misaki, Tayo Kawazu, Kohno, Shigeru, Shigeru Kohno, Tomoya Nishino, Masanobu Miyazaki, Tadashi Uramatsu, Yoko Obata, Kawazu, Tayo   +17 more
core   +1 more source

A CD2AP Mutation Associated with Focal Segmental Glomerulosclerosis in Young Adulthood [PDF]

, 2016
Mutations in CD2-associated protein (CD2AP) have been identified in patients with focal segmental glomerulosclerosis (FSGS); however, reports of CD2AP mutations remain scarce.
Yoland Marie Anistan, Hohmann, M., Tsvetkov, D., Rudolph, B., Mannaa, M., Harteneck, C., Birgit Rudolph, Dmitry Tsvetkov, Maik Gollasch, Gollasch, M., Christian Harteneck, Anistan, Y.M., Marwan Mannaa, Michael Hohmann, Yol, Marie Anistan   +15 more
core   +1 more source

Pathophysiology of focal segmental glomerulosclerosis [PDF]

Pediatric Nephrology, 2007
Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease progression in FSGS. This article reviews some of the
Reidy, Kimberly, Kaskel, Frederick J.
openaire   +2 more sources

Cyclophosphamide in the treatment of focal segmental glomerulosclerosis [PDF]

Brazilian Journal of Medical and Biological Research, 2004
Prednisone is the initial treatment of primary focal segmental glomerulosclerosis. However, when immunosuppressive agents in combination with steroids are used in the treatment of prednisone-dependent and prednisone-resistant patients the remission rate ...
R. Martinelli, L.J. Pereira, O.M.M. Silva, A.S. Okumura, H. Rocha   +4 more
doaj   +1 more source