Results 21 to 30 of about 45,138 (251)

A CD2AP Mutation Associated with Focal Segmental Glomerulosclerosis in Young Adulthood [PDF]

, 2016
Mutations in CD2-associated protein (CD2AP) have been identified in patients with focal segmental glomerulosclerosis (FSGS); however, reports of CD2AP mutations remain scarce.
Yoland Marie Anistan, Hohmann, M., Tsvetkov, D., Rudolph, B., Mannaa, M., Harteneck, C., Birgit Rudolph, Dmitry Tsvetkov, Maik Gollasch, Gollasch, M., Christian Harteneck, Anistan, Y.M., Marwan Mannaa, Michael Hohmann, Yol, Marie Anistan   +15 more
core   +1 more source

Intraglomerular Monocyte/Macrophage Infiltration and Macrophage–Myofibroblast Transition during Diabetic Nephropathy Is Regulated by the A_2B Adenosine Receptor

Cells, 2020
Diabetic nephropathy (DN) is considered the main cause of kidney disease in which myofibroblasts lead to renal fibrosis. Macrophages were recently identified as the major source of myofibroblasts in a process known as macrophage–myofibroblast transition (
Ángelo Torres, Katherin Muñoz, Yessica Nahuelpán, Angelo-Paolo R. Saez, Pablo Mendoza, Claudia Jara, Claudio Cappelli, Raibel Suarez, Carlos Oyarzún, Claudia Quezada, Rody San Martín   +10 more
doaj   +1 more source

Adult-Onset Genetic Focal Segmental Glomerulosclerosis: A Tale of Two Mutations

Revista Portuguesa de Nefrologia e Hipertensão, 2023
Focal segmental glomerulosclerosis (FSGS) is a kidney histologic lesion that may be caused by multiple aetiologies and pathophysiological mechanisms, with podocyte injury and depletion as the common denominator.
Luís Leite de Sousa, Gonçalo Pimenta, Rita Veríssimo, Rita Theias, Tiago Carvalho   +4 more
doaj   +1 more source

Inhibition of the soluble epoxide hydrolase promotes albuminuria in mice with progressive renal disease [PDF]

, 2010
Epoxyeicotrienoic acids (EETs) are cytochrome P450-dependent anti-hypertensive and anti-inflammatory derivatives of arachidonic acid, which are highly abundant in the kidney and considered reno-protective.
Geisslinger, Gerd, Gerd Geisslinger, Tsai, Cindy, Ralf P. Brandes, Brandes, Ralf, Schäfer, Liliana, Amann Kerstin, Liliana Schaefer, Kerstin Amann, Felix Jansen, Jung, Oliver, Ralf P Brandes, Mieth Anja, Hwang Sung H., Schaefer Liliana, Anja Mieth, Hwang, Sung H., Barbosa-Sicard Eduardo, Sung H. Hwang, Bruce D. Hammock, Hammock Bruce D., Christophe Morisseau, Cindy Tsai, Rainer U. Pliquett, Oliver Jung, Brandes Ralf P., Pliquett Rainer U., Mieth, Anja, Babelova, Andrea, Barbosa Sicard, Eduardo, Geisslinger Gerd, Jansen, Felix, Andrea Babelova, Sung H Hwang, Morisseau, Christophe, Pliquett, Rainer U., Eduardo Barbosa-Sicard, Jung Oliver, Rainer U Pliquett, Bruce D Hammock, Jansen Felix, Tsai Cindy, Morisseau Christophe, Amann, Kerstin, Hammock, Bruce D., Babelova Andrea   +45 more
core   +2 more sources

ATRA attenuate proteinuria via downregulation of TRPC6 in glomerulosclerosis rats induced by adriamycin

Renal Failure, 2018
Objective: In this research, we explored the molecular mechanism of proteinuria in glomerulosclerosis rats and the protective effects of ATRA. Methods: This research set up three groups: SHO group, GS group, and ATRA group (15 mg/(kg d), Sigma, St. Louis,
Lei Zhang, Xiu-Ping Chen, He Qin, Ling Jiang, Yuan-Han Qin   +4 more
doaj   +1 more source

GLOMERULOSCLEROSIS

The Professional Medical Journal, 2009
Objective: Objective is to determine the changes in lipids and lipoproteins in patients with glomerulosclerosis and healthy controls.Place and Duration: Department of Biochemistry, Frontier Medical College, Abbottabad with the collaboration of Nephrology Unit, AyoubMedical Complex, Abbottabad. April, 2006 February 2007.
TASNEEM ZAFAR, ZAFAR IQBAL
openaire   +2 more sources

The effect of porang (Amorphophallus muelleri) extract on renal histopathological changes

Journal of Advanced Pharmaceutical Technology & Research
Diabetes mellitus is a chronic condition defined by elevated blood sugar levels (hyperglycemia). This condition can lead to complications such as nephropathy, which is histologically shown with glomerulosclerosis.
Evan Ricardo, Bernadette Dian Novita, Niluh Suwasanti, Jovan Amadeo Muliyanto, I Gusti Agung Putu Diah Meliana Dewi, Ferdinand Jaya   +5 more
doaj   +1 more source

Prognostic factors in glomerular diseases with crescents

Romanian Journal of Internal Medicine, 2019
Introduction. More than 50% of glomerular crescent formation is required for a diagnosis of crescentic glomerulonephritis in a kidney biopsy. Although treatment protocols have been established for diffuse crescentic glomerulonephritis, there is no ...
Yeter Hasan Haci, Gonul Ipek, Demirel Ertugrul, Korucu Berfu, Derici Ulver   +4 more
doaj   +1 more source

Focal Segmental Glomerulosclerosis [PDF]

Clinical Journal of the American Society of Nephrology, 2017
Focal segmental glomerulosclerosis (FSGS) is a leading cause of kidney disease worldwide. The presumed etiology of primary FSGS is a plasma factor with responsiveness to immunosuppressive therapy and a risk of recurrence after kidney transplant–important disease characteristics.
Avi Z, Rosenberg, Jeffrey B, Kopp
openaire   +2 more sources

Value of original and modified pathological scoring systems for prognostic prediction in paraffin-embedded donor kidney core biopsy

Renal Failure
Background No study has validated, compared and adapted scoring systems for prognosis prediction based on donor kidney core biopsy (CB), with less glomeruli than wedge biopsy.Methods A total of 185 donor kidney CB specimens were reviewed using seven ...
Jinghong Tan, Huanxi Zhang, Longshan Liu, Jun Li, Qian Fu, Yan Li, Chenglin Wu, Ronghai Deng, Jiali Wang, Bowen Xu, Wenfang Chen, Shicong Yang, Changxi Wang   +12 more
doaj   +1 more source