Results 41 to 50 of about 75,218 (96)

Intestinal interleukin-22 enhances GLP-1 production via the STAT3 pathway to improve glucose homeostasis during high-fat diet induced obesity in a study with male mice

Nature Communications
Metabolic disorders such as obesity and diabetes are influenced by glucagon-like peptide-1 (GLP-1), which regulates insulin secretion. Interleukin (IL)−22 maintains intestinal barrier function, yet its role in metabolic regulation remains unclear.
Chae-Won Kim, Jae-Hee Ahn, Bo Ra Lee, Hong Min Kim, Youngjoo Han, Jae-Hyeon Jeong, Jaewon Cho, Hyunjin Jeong, Dae-Joon Kim, Seong-Eun Kim, Jeon-Kyung Kim, Yu-Bin Lee, Su Min Kim, Hye Hyun Yoo, Eun Hye Lee, Su Ryeon Seo, Kyung Bong Ha, Eun Soo Lee, Mi-Na Kweon, Hong Pyo Kim, Sun-Young Chang, Choon Hee Chung, Hyun-Jeong Ko   +22 more
doaj   +1 more source

GLP-1 receptor agonists in IBD: exploring the crossroads of metabolism and inflammation

Frontiers in Immunology
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) represent a cornerstone in the treatment of diabetes and obesity and have emerged as a promising option for other metabolic disorders, including hepatic steatosis.
Giulia Migliorisi, Giulia Migliorisi, Roberto Gabbiadini, Arianna Dal Buono, Matteo Ferraris, Matteo Ferraris, Giuseppe Privitera, Giuseppe Privitera, Lorenzo Petronio, Lorenzo Petronio, Peter Bertoli, Peter Bertoli, Cristina Bezzio, Cristina Bezzio, Alessandro Armuzzi, Alessandro Armuzzi   +15 more
doaj   +1 more source

Serum levels of glucagon-like peptide (GLP)-1 and GLP-2 in patients with Hashimoto′s thyroiditis

Journal of Research in Medical Sciences, 2015
Background: The influence of Hashimoto′s thyroiditis (HT) with subclinical hypothyroidism or euthyroid status on the alteration of glucagon-like peptide (GLP)-1 and GLP-2 levels remains uncertain.
Yue Jin, Hong Liu, Shao-Gang Ma, Jian-Ping Cheng, Kai Zhang   +4 more
doaj  

Unlocking the multifaceted roles of GLP-1: Physiological functions and therapeutic potential

Toxicology Reports
Glucagon (GCG) like peptide 1 (GLP-1) has emerged as a powerful player in regulating metabolism and a promising therapeutic target for various chronic diseases.
Tohada M. AL-Noshokaty, Rehab Abdelhamid, Nourhan M. Abdelmaksoud, Aya Khaled, Mariam Hossam, Razan Ahmed, Toka Saber, Shahd Khaled, Shereen Saeid Elshaer, Ahmed I. Abulsoud   +9 more
doaj   +1 more source

GLP-1 RA and dual GIP/GLP-1 RA treatment in MODY: a descriptive case series

BMJ Open Diabetes Research & Care
Introduction Glucagon-like peptide-1 receptor agonists (GLP-1 RA) and dual glucose insulinotropic polypeptide (GIP)/GLP-1 RA are widely prescribed, but their effectiveness in different subtypes of maturity-onset diabetes of the young (MODY) is unknown ...
William H Herman, Elif A Oral, Rochelle N Naylor, Brigid Gregg, Alina Z Mehdi, Lily Deng, Colby L Chase, Maria Cristina Foss-Freitas, Mansa Krishnamurthy, David T Broome   +9 more
doaj   +1 more source

Cardioprotective effects of GLP‐1(28‐36a): A degraded metabolite or GLP‐1’s better half?

Journal of Diabetes Investigation, 2020
Yangyang Liu, Sodai Kubota, Katsumi Iizuka, Daisuke Yabe   +3 more
doaj   +1 more source

Are Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Central Nervous System (CNS) Penetrant: A Narrative Review

Neurology and Therapy
Introduction Glucagon-like peptide-1 (GLP-1) is an incretin hormone that modulates glucose metabolism and insulin secretion. Recent translational and clinical research has evaluated the effects of GLP-1 receptor agonists (GLP-1 RAs), a class of drugs ...
Juliana West, Maggie Li, Sabrina Wong, Gia Han Le, Kayla M. Teopiz, Kyle Valentino, Christine E. Dri, Roger S. McIntyre   +7 more
doaj   +1 more source

GLP-1-based therapies for type 2 diabetes: from single, dual and triple agonists to endogenous GLP-1 production and L-cell differentiation

Diabetology & Metabolic Syndrome
Glucagon-like peptide-1 (GLP-1) is an incretin peptide hormone mainly secreted by enteroendocrine intestinal L-cells. GLP-1 is also secreted by α-cells of the pancreas and the central nervous system (CNS). GLP-1 secretion is stimulated by nutrient intake
Maedeh Movahednasab, Hassan Dianat-Moghadam, Sana Khodadad, Reza Nedaeinia, Saeid Safabakhsh, Gordon Ferns, Rasoul Salehi   +6 more
doaj   +1 more source

Revolutionizing disease treatment through bioengineered probiotics and glucagon‐like peptide 1 (GLP‐1) based strategies: A path towards effective cures

Food Bioengineering
Human intestinal gut microbiota harbors complex and diverse microbes that play an important role in maintaining the homeostasis of the intestinal microenvironment in humans.
Smriti Jain, Adarsh Kumar Shukla, Deepika, Surbhi Panwar, Anita Kumari, Ashok Kumar Yadav, Ashwani Kumar   +6 more
doaj   +1 more source

GLP-1 and the cardiovascular system. [PDF]

J Clin Invest
Kahles F, Birkenfeld AL, Marx N.
europepmc   +1 more source