Results 231 to 240 of about 28,560,894 (288)
Review Article: Fibrosis‐4 Index in Steatotic Liver Disease—Past, Present and Future
Alimentary Pharmacology &Therapeutics, EarlyView.FIB‐4 remains an inexpensive, scalable first‐line triage tool for excluding advanced fibrosis and identifying patients who need second‐line assessment, but it should not be used as a stand‐alone diagnostic or treatment‐selection test. Sequential testing and longitudinal FIB‐4 trajectories may improve risk stratification and prognosis.
Kriti Soni +6 more
wiley +1 more source
Localization of Glucagon-Like Peptide-2 Receptor Expression in the Mouse.
Endocrinology, 2019 Yusta B +5 more
europepmc +1 more source
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Scandinavian Journal of Gastroenterology, 2004
GLP-1 (glucagon-like peptide-1) and GLP-2 (glucagon-like peptide-2) are released in equimolar amounts in response to meal ingestion. GLP-1 inhibits gastric emptying and reduces postprandial gastric and exocrine pancreatic secretion and may play a physiological regulatory role in controlling appetite and energy intake in humans.
Jens Juul Holst +2 more
exaly +3 more sources
GLP-1 (glucagon-like peptide-1) and GLP-2 (glucagon-like peptide-2) are released in equimolar amounts in response to meal ingestion. GLP-1 inhibits gastric emptying and reduces postprandial gastric and exocrine pancreatic secretion and may play a physiological regulatory role in controlling appetite and energy intake in humans.
Jens Juul Holst +2 more
exaly +3 more sources
Annual Review of Nutrition, 2006
▪ Abstract Multiple peptide hormones produced within the gastrointestinal system aid in the regulation of energy homeostasis and metabolism. Among these is the intestinotrophic peptide glucagon-like peptide-2 (GLP-2), which is released following food intake and plays a significant role in the adaptive regulation of bowel mass and mucosal integrity ...
Jennifer L, Estall, Daniel J, Drucker
openaire +2 more sources
▪ Abstract Multiple peptide hormones produced within the gastrointestinal system aid in the regulation of energy homeostasis and metabolism. Among these is the intestinotrophic peptide glucagon-like peptide-2 (GLP-2), which is released following food intake and plays a significant role in the adaptive regulation of bowel mass and mucosal integrity ...
Jennifer L, Estall, Daniel J, Drucker
openaire +2 more sources
Glucagon-like peptide-1 and glucagon-like peptide-2
Best Practice & Research Clinical Endocrinology & Metabolism, 2004The glucagon-like peptides (glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-2 (GLP-2)) are released from enteroendocrine cells in response to nutrient ingestion. GLP-1 enhances glucose-stimulated insulin secretion and inhibits glucagon secretion, gastric emptying and feeding. GLP-1 also has proliferative, neogenic and antiapoptotic effects on
Laurie L. Baggio, Daniel J. Drucker
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Microcirculation, 2019
AbstractGLP‐1 and GLP‐2 are gut‐derived hormones used in the treatment of diabetes type‐2 and short bowel syndrome, respectively. GLP‐1 attenuates insulin resistance and GLP‐2 reduces enterocyte apoptosis and enhances crypt cell proliferation in the small intestine. In addition, both hormones have vasoactive effects and may be useful in situations with
Nikolaj Nerup +5 more
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AbstractGLP‐1 and GLP‐2 are gut‐derived hormones used in the treatment of diabetes type‐2 and short bowel syndrome, respectively. GLP‐1 attenuates insulin resistance and GLP‐2 reduces enterocyte apoptosis and enhances crypt cell proliferation in the small intestine. In addition, both hormones have vasoactive effects and may be useful in situations with
Nikolaj Nerup +5 more
openaire +3 more sources
Journal of Clinical Endocrinology & Metabolism, 1999
Glucagon-like peptide 2 (GLP-2) is a 33 amino acid peptide-encoded carboxyterminal to the sequence of GLP-1 in the proglucagon gene. Both GLP-1 and GLP-2 are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms of action.
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Glucagon-like peptide 2 (GLP-2) is a 33 amino acid peptide-encoded carboxyterminal to the sequence of GLP-1 in the proglucagon gene. Both GLP-1 and GLP-2 are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms of action.
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Glucagon-like peptide 2: an update
Current Opinion in Endocrinology & Diabetes, 2005Purpose of review Glucagon-like peptide 2 (GLP-2) is a 33-amino acid peptide secreted in a nutrient-dependent manner from gut enteroendocrine cells. The proliferative and antiapoptotic actions of GLP-2 lead to expansion of the mucosal surface area and enhanced capacity for nutrient absorption in multiple models of experimental intestinal injury.
Eric D Shin +2 more
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Canadian Journal of Physiology and Pharmacology, 2003
The proglucagon-derived peptide family consists of three highly related peptides, glucagon and the glucagon-like peptides GLP-1 and GLP-2. Although the biological activity of glucagon as a counter-regulatory hormone has been known for almost a century, studies conducted over the past decade have now also elucidated important roles for GLP-1 as an ...
Patricia L, Brubaker, Younes, Anini
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The proglucagon-derived peptide family consists of three highly related peptides, glucagon and the glucagon-like peptides GLP-1 and GLP-2. Although the biological activity of glucagon as a counter-regulatory hormone has been known for almost a century, studies conducted over the past decade have now also elucidated important roles for GLP-1 as an ...
Patricia L, Brubaker, Younes, Anini
openaire +2 more sources
Journal of Molecular Recognition, 2012
Glucagon‐like peptide‐2 (GLP‐2) is a member of the glucagon multigene family that is produced by intestinal enteroendocrine cells in response to food intake. GLP‐2 stimulates growth of the intestinal epithelium, enhances its barrier functions, and increases nutrient uptake.
Audrey E, Baker +7 more
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Glucagon‐like peptide‐2 (GLP‐2) is a member of the glucagon multigene family that is produced by intestinal enteroendocrine cells in response to food intake. GLP‐2 stimulates growth of the intestinal epithelium, enhances its barrier functions, and increases nutrient uptake.
Audrey E, Baker +7 more
openaire +2 more sources