Entero-insular axis in children with simple obesity [PDF]
Pediatric Endocrinology, Diabetes and Metabolism, 2009 Introduction: The entero-insular axis plays an important role in generation ofsatiety signal. Thus, disturbances in this axis can influence the path to a simple obesity.
Jerzy Starzyk +2 more
doaj
Hypoglycaemic crisis induced by non-islet cell tumours in two dogs
Veterinární Medicína, 2019 Two dogs were admitted for the diagnosis and treatment of neoplasia (a hepatic and a mammary tumour, respectively), lethargy, quadriparesis and abnormal mentation with hypoglycaemia.
Hakhyun Kim +3 more
doaj +1 more source
Robust Estimation of the Weighted Average Treatment Effect for A Target Population [PDF]
arXiv, 2018 The weighted average treatment effect (WATE) is a causal measure for the comparison of interventions in a specific target population, which may be different from the population where data are sampled from. For instance, when the goal is to introduce a new treatment to a target population, the question is what efficacy (or effectiveness) can be gained ...
arxiv
Insulin and Metformin are Associated With Reduced Risk of Amyotrophic Lateral Sclerosis
Chronic Diseases and Translational Medicine, EarlyView.Human insulin heterodimer (A). Human insulin heterodimer (dark blue) docked within center of Cx43 channel (B) Abstract Background Type 2 diabetes (T2D), but not type 1, protected against amyotrophic lateral sclerosis (ALS). In T2D serum insulin is normal or elevated in the early stages.
Steven Lehrer, Peter H. Rheinstein
wiley +1 more source
ANALYSIS OF THE BLOOD SUGAR RESPONSE OF OBESE-HYPERGLYCEMIC MICE AND NORMAL MICE TO HORMONES: INSULIN, GLUCAGON, AND EPINEPHRINE1 [PDF]
, 1956 Kenneth H. Shull +2 more
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Tryptophan‐Selective Chemical Modification of Peptides by Thioether‐Mediated Sulfenylation
ChemistryEurope, EarlyView.A thioether‐mediated sulfenylation method based on 4‐fluorophenyl 3‐nitro‐2‐pyridinesulfenate (Npys‐OPh(pF)) is developed for Trp‐selective chemical modification. This sulfenylation proceeds under mild, metal‐free, and weakly acidic conditions and is broadly applicable to the chemical modification of various Trp‐containing peptides as well as the late ...
Hayate Shida +11 more
wiley +1 more source
Glucagon Receptor Signaling and Lipid Metabolism
Frontiers in Physiology, 2019 Glucagon is secreted from the pancreatic alpha cells upon hypoglycemia and stimulates hepatic glucose production. Type 2 diabetes is associated with dysregulated glucagon secretion, and increased glucagon concentrations contribute to the diabetic ...
Katrine D. Galsgaard +11 more
doaj +1 more source
EFFECTS OF GLUCAGON ON RENAL FUNCTION IN MAN* [PDF]
, 1958 Harold Elrick +6 more
openalex +1 more source
Chemistry – A European Journal, Accepted Article.Short amyloidogenic oligopeptides (APRs) are proposed as early macromolecules capable of forming solvent‐separated nanosystems under prebiotic conditions. This study provides experimental evidence that APRs, such as the aggregation‐prone oligopeptide A (APR‐A), can undergo mutational transitions to form distinct variants, and convert to APR‐B, either ...
Fruzsina Bencs +7 more
wiley +1 more source
THE PHYSIOLOGIC SIGNIFICANCE OF THE SECRETION OF ENDOGENOUS INSULIN INTO THE PORTAL CIRCULATION. I. COMPARISON OF THE EFFECTS OF GLUCAGON-FREE INSULIN ADMINISTERED VIA THE PORTAL VEIN AND VIA A PERIPHERAL VEIN ON THE MAGNITUDE OF HYPOGLYCEMIA AND PERIPHERAL GLUCOSE UTILIZATION1 [PDF]
, 1958 Leonard L. Madison, Roger H. Unger
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