Results 91 to 100 of about 140,006 (312)
, 1998 cAMP is required for normal glucose-induced insulin release by pancreatic beta-cells. In a previous study, we showed that cAMP production in beta-cells depends on the expression of receptors for glucagon, glucagon-like peptide 1(7-36) amide [GLP-1(7-36 ...
Schuit, Frans +5 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims In this study, we examined the effects of assigning partial credit to selected answer choices on student performance and perceptions in a pharmacology course using Type A multiple‐choice questions (MCQs). Methods Partial credit scoring was incorporated into quizzes and exams in a 10‐week pharmacology course for postbaccalaureate premedical ...
Stephen D. Schneid +2 more
wiley +1 more source
The role of incretin hormones in glucagon regulation and diabetes treatment
, 2013 Incretins are hormones that are secreted by the gut upon feeding; their release alerts the pancreatic islets that nutrients will come through the gastrointestinal tract and islets start priming by vagal stimulation (Boron and Boulpaep, 2005).
Al-Lafi S.M. +4 more
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British Journal of Clinical Pharmacology, EarlyView.Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley +1 more source
Evaluation of Beta-Cell Function in Diabetic Taiwanese Children Using a 6- Min Glucagon Test
, 2011 This study evaluates the effects of glucagon 30 mu g/kg ( maximal 1 mg) on beta-cell function in children by C-peptide determined before and 6 min after intravenous administration.
童怡靖;李俊賢;蔡文友;蕭佩宏 +1 more
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Assessing the Catalytic Role of Native Glucagon Amyloid Fibrils
Glucagon stands out as a pivotal peptide hormone, instrumental in controlling blood glucose levels and lipid metabolism. While the formation of glucagon amyloid fibrils has been documented, their biological functions remain enigmatic.
Elad, Arad +4 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić +7 more
wiley +1 more source
Glucagon Be-Gone: A Cure for Type 1 Diabetes?
, 2021 Cells within the pancreas produce the hormones insulin and glucagon, which have opposing actions on blood glucose. Insulin decreases blood glucose levels by promoting the utilization and storage of glucose while simultaneously repressing glucagon ...
Holland, W.
core
Frontiers in Immunology, 2018 Systemic lupus erythematosus (SLE) patients may show increased insulin resistance (IR) when compared with their healthy peers. Exercise training has been shown to improve insulin sensitivity in other insulin-resistant populations, but it has never been ...
Fabiana B. Benatti +11 more
doaj +1 more source
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
British Journal of Clinical Pharmacology, EarlyView.Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source