Results 171 to 180 of about 140,006 (312)

GLP-1 Agonists in Adolescent Obesity: A Narrative Review of Single, Dual, and Triple Agonists. [PDF]

Diabetes Metab Syndr Obes
Abid M, Sheikh KS, Ahmad MS, Jiang H.
europepmc   +1 more source

Postprandial Glucagon Action in the Human Brain. [PDF]

Diabetes Obes Metab
Wagner R, Kullmann S, Hummel J, Prystupa K, Hosenfeld E, Veit R, Birkenfeld AL, Häring HU, Preissl H, Fritsche A, Peter A, Heni M.   +11 more
europepmc   +1 more source

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

Anterior Cutaneous Nerve Entrapment Syndrome From Glucagon-Like Peptide-1 Receptor Agonist Injection. [PDF]

ACG Case Rep J
Singh N, Chaparro E, Shapiro JM, Husu EN.   +3 more
europepmc   +1 more source

High‐Fat Diet Exacerbates Neuropathology in a Transgenic Mouse Model of Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Multiple system atrophy (MSA) is a rare and devastating neurodegenerative disorder. Accumulating clinical and preclinical evidence suggests that diabetes and insulin resistance may adversely influence MSA pathophysiology. Objective We investigated the potential association between diabetes, impaired glucose homeostasis, and MSA ...
Marie‐Laure Arotcarena, Anna Delamarre, Miguel Lopez‐Cuina, Hugo Martin, Elio Balpe, Xavier Fioramonti, Erwan Bezard, Wassilios G. Meissner   +7 more
wiley   +1 more source

Experimental chronic fetal hyperglucagonemia stimulates hepatic pathways for amino acid catabolism and gluconeogenesis. [PDF]

J Endocrinol
Tanner AR, Cilvik SN, Nguyen MA, Brown LD, Anthony RV, Wright CJ, Wesolowski SR, Rozance PJ.   +7 more
europepmc   +1 more source

AI‐Driven Synthesis in Medicinal Chemistry: Integrating Large Language Models, Robotic Automation, and Sustainability Metrics to Accelerate Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT Artificial intelligence (AI) is transforming synthetic chemistry from task‐specific predictors into integrated platforms that unify retrosynthesis, reaction optimization, and closed‐loop robotic automation. This review highlights how AI‐assisted planning and robotic execution shorten cycle times, reduce step counts, and improve route ...
Amit Gangwal, Antonio Lavecchia
wiley   +1 more source

The Regulation of Metabolic Homeostasis by Incretins and the Metabolic Hormones Produced by Pancreatic Islets

Diabetes, Metabolic Syndrome and Obesity
Joshua Reed, Stephen C Bain, Venkateswarlu Kanamarlapudi Institute of Life Science, Medical School, Swansea University, Swansea, SA2 8PP, UKCorrespondence: Venkateswarlu Kanamarlapudi, Institute of Life Science, Medical School, Swansea University ...
Reed J, Bain SC, Kanamarlapudi V
doaj  

Morning glucagon disrupts insulin induced hepatic metabolic memory and subsequent afternoon glucose metabolism in canines. [PDF]

Front Endocrinol (Lausanne)
Waterman HL, Smith MS, Farmer B, Yankey K, Bosma KJ, O'Brien RM, Claxton DP, Howard T, Kraft G, Cherrington AD, Edgerton DS.   +10 more
europepmc   +1 more source

Weight Loss Intentionality and Strategies in Urinary Incontinence

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Urinary incontinence (UI)−including stress (SUI), urge (UUI), and mixed (MUI) subtypes−is associated with obesity, and weight loss is commonly recommended for intervention. However, the comparative effects of intentionality and weight loss strategies on UI severity remain poorly defined.
Eric S. Chai, Jonathan T. Ryan, Vismitha Naik, Nicolas Tapia‐Stoll, Katherine A. Amin, Ricardo Palmerola, Adam Williams, Raveen Syan   +7 more
wiley   +1 more source