Results 191 to 200 of about 114,449 (265)

Mapping histologic and functional maturation of human endocrine pancreas across early postnatal periods. [PDF]

Nat Commun
Saunders DC, Feng F, Hopkirk AL, Aamodt KI, Hart N, Pan FC, Reihsmann CV, Izmaylov N, Mei S, Sherrod BA, Davis C, Nonpanya N, Pettway YD, Patel KP, Lee KS, Duryea J, Haliyur R, Aramandla R, Durai H, Poffenberger G, Martin A, Posgai AL, Kusmartseva I, Beery ML, Yang M, Xu K, Kang H, Greiner DL, Shultz LD, Cartailler JP, Bottino R, Atkinson MA, Wright CVE, Powers AC, Brissova M.   +34 more
europepmc   +1 more source

Glucagon‐like peptide‐1 receptor agonist use and violent crime among US adults

Criminology, EarlyView.
Abstract Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs), a class of medications widely prescribed for diabetes and obesity, have exhibited emerging effects on substance use, reward processing, and impulse control. This study examines whether current GLP‐1 RA use moderates established behavioral pathways to violent crime from impulsivity and ...
Daniel C. Semenza, Christopher Thomas
wiley   +1 more source

Altered Glucagon Response to Oral Glucose in Individuals at Different Stages of Type 1 Diabetes Development.

J Clin Endocrinol Metab
Kontola H, Crisóstomo L, Löyttyniemi E, Koskenniemi JJ, Veijola R, Toppari J, Kero J.   +6 more
europepmc   +1 more source

Rationale, design and baseline characteristics of the TRANSCEND-CKD trial of retatrutide in patients with chronic kidney disease. [PDF]

Nephrol Dial Transplant
Heerspink HJL, van Raalte DH, Bjornstad P, Bunck MC, Wu P, Tunali I, Milicevic Z, Koeneman L.   +7 more
europepmc   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

eNAMPT induces alpha-cell mass expansion but impaired glucagon counter regulatory response.

Endocrinology
Sayers SR, Gesheva VS, Varghese JJ, Beavil R, Zhao M, Cheah Y, Hopkins D, Fine NHF, Hasib A, Hodson DJ, Caton PW.   +10 more
europepmc   +1 more source

Recent advances in incretin biology and therapeutics: From glucose-dependent insulinotropic polypeptide reappraisal to next-generation agonists. [PDF]

J Diabetes Investig
Kubota S, Seino Y, Yabe D.
europepmc   +1 more source

Genomic Investigations Unveil the Genetic Underpinnings of Environmental Adaptation in African Goat Populations

Integrative Zoology, EarlyView.
This study integrates genomics and landscape genetics to analyze African goat environmental adaptation. Analyzing 1591 samples, it finds population structure differentiates geographically into four groups, with gene flow between wild Yura goats and North Africans.
Weifeng Peng, Yihua Wang, Yiyuan Zhang, Lei Gao, Lili Wu, Shuping Wang, Yiyang Gao, Wanlu Shi, Kaixin Lu, Rong Deng, Junting Li, Jing Han, Xiaohui Lu, Yujie Liu, Xiaojiao Tang, Yunxia Zhang, Guoyin Li, Li Huang, Mingsheng Yang, Xiaoyan Li   +19 more
wiley   +1 more source

CHD4 and NKX2.2 Cooperate to Regulate β-Cell Function by Repressing Non-β-Cell Gene Programs. [PDF]

Diabetes
Sarbaugh D, Oliveira TG, Guney MA, Casey MR, Hoelscher VM, Hill CJ, Michel CR, Wells KL, Benninger RKP, Sussel L.   +9 more
europepmc   +1 more source

GLP-1, GIP, and Glucagon Excursions During a Mixed Meal Tolerance Test in Young and Lean South Asians Versus Europids. [PDF]

Diabetes Obes Metab
Hoekx CA, Brinkman LBD, van Eenige R, Kooijman S, Muskiet MHA, Jazet IM, Martinez-Tellez B, Rensen PCN, Boon MR.   +8 more
europepmc   +1 more source