Results 31 to 40 of about 222,938 (359)

Abnormal late postprandial glucagon response in type 1 diabetes is a function of differences in stimulated C-peptide concentrations

open access: yesFrontiers in Endocrinology
BackgroundThe functional changes in alpha cells in patients with type 1 diabetes (T1D) with different residual beta cell functions remain poorly elucidated.
Lingyu Zhang   +7 more
doaj   +1 more source

The associations of incretin hormone concentration with gestational diabetes mellitus

open access: yesСахарный диабет, 2016
Background: Enteropancreatic hormonal system disorder is a possible reason for β-cell dysfunction and carbohydrate metabolism disorder among pregnant women. However, no information is available about the state of enteroinsulin hormones [glucagon, glucose-
Tatiana V. Saprina   +7 more
doaj   +1 more source

Optimal Regulation of Blood Glucose Level in Type I Diabetes using Insulin and Glucagon

open access: yes, 2019
The Glucose-Insulin-Glucagon nonlinear model [1-4] accurately describes how the body responds to exogenously supplied insulin and glucagon in patients affected by Type I diabetes.
Della Rossa, Fabio   +4 more
core   +4 more sources

Circulating free fatty acids, insulin, and glucose during chemical stimulation of hypothalamus in rats [PDF]

open access: yes, 1984
The aim of this study was to investigate plasma free fatty acids (FFA), insulin, and blood glucose during chemical stimulation of the lateral and ventromedial hypothalamic areas (LHA and VMH) in rats.
Damsma, G.,   +3 more
core   +1 more source

Incretins today: multiple effects and therapeutic potential

open access: yesСахарный диабет, 2019
Glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1) are the incretin hormones initially discovered in the 1960s. GIP and GLP-1 have gained great scientific interest due to their properties in increasing insulin secretion ...
Oksana V. Tsygankova   +2 more
doaj   +1 more source

The Physiology of Glucagon [PDF]

open access: yesJournal of Diabetes Science and Technology, 2010
This short review outlines the physiology of glucagon in vivo, with an emphasis on its neural control, the author's area of interest. Glucagon is secreted from alpha cells, which are a minority of the pancreatic islet. Anatomically, they are down stream from the majority islet beta cells.
openaire   +2 more sources

Foundational contributions of Svetlana Mojsov to the GLP-1 field [PDF]

open access: yesExploration of Drug Science
Biochemist Svetlana Mojsov, both as a graduate student at The Rockefeller University under the mentorship of Bruce Merrifield during the 1970s, and as an independent investigator at the Massachusetts General Hospital (MGH) during the 1980s, devised ...
George Barany, Michael J. Barany
doaj   +1 more source

Case report: Fatal insulin overdose in a dog with type 1 diabetes mellitus—characteristics and successful management

open access: yesFrontiers in Veterinary Science, 2023
Administering more than 10 times the therapeutic dose of insulin is extremely rare in diabetic dogs and is life threatening with hypoglycemia and seizures if not accompanied by appropriate treatment.
Jun-Hyeong Park   +7 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Studies of the development of diabetic ketosis in the rat

open access: yesJournal of Lipid Research, 1972
Plasma glucose, free fatty acid, ketone, and triglyceride concentrations were measured at frequent intervals after the administration of alloxan to rats. Hepatic triglyceride levels were determined in the same animals.
Jürgen M. Meier   +4 more
doaj   +1 more source

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