Recent advances in mathematical modeling and statistical analysis of exocytosis in endocrine cells [PDF]
, 2016 open5noMost endocrine cells secrete hormones as a result of Ca(2+)-regulated exocytosis, i.e., fusion of the membranes of hormone-containing secretory granules with the cell membrane, which allows the hormone molecules to escape to the extracellular ...
Cortese, Giuliana +4 more
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The relationship between glucose and the liver-alpha cell axis – A systematic review
Frontiers in Endocrinology, 2023 Until recently, glucagon was considered a mere antagonist to insulin, protecting the body from hypoglycemia. This notion changed with the discovery of the liver-alpha cell axis (LACA) as a feedback loop.
Thomas Pixner +23 more
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Glycemia Regulation: From Feedback Loops to Organizational Closure. [PDF]
, 2020 Endocrinologists apply the idea of feedback loops to explain how hormones regulate certain bodily functions such as glucose metabolism. In particular, feedback loops focus on the maintenance of the plasma concentrations of glucose within a narrow range ...
Bich, Leonardo +2 more
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SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels [PDF]
, 2019 学位記番号 ...
Suga, Takayoshi +2 more
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Spinally projecting preproglucagon axons preferentially innervate sympathetic preganglionic neurons [PDF]
, 2014 Glucagon-like peptide-1 (GLP-1) affects central autonomic neurons, including those controlling the cardiovascular system, thermogenesis, and energy balance.
Gribble, FM +5 more
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Protective potential of glucagon like peptide 2 (GLP-2) against the neurodegeneration [PDF]
, 2019 Neurodegeneration consists in loss of neuron specific types, pattern and distribution, leading to progressive dysfunctions of the central nervous system.
Amato, Antonella, Mulè, Flavia
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Gut, 1975 The effect of glucagon on human colonic myoelectrical activity is described. By means of intraluminal, serosal, and surface electrodes, recordings from all areas of the large bowel have been obtained. Glucagon inhibited both electrical and pressure rhythms in all subjects tested. Evidence is produced to suggest a direct action on colonic smooth muscle.
I. Taylor +3 more
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The cardiovascular safety of incretin-based therapies: a review of the evidence [PDF]
, 2013 Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in people with diabetes and therefore managing cardiovascular (CV) risk is a critical component of diabetes care. As incretin-based therapies are effective recent additions to the
Petrie, J.R.
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Glucagon: Physiological and Pharmacological Functions and Pathophysiological Significance in Type 2 Diabetes [PDF]
Endocrinology and MetabolismGlucagon has many functions, including the promotion of hepatic glucose production, fatty acid oxidation, thermogenesis, energy consumption, lipolysis, and myocardial contraction, as well as the suppression of lipogenesis, appetite, and gastrointestinal ...
Tadahiro Kitamura
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Glucagonoma without glucagonoma syndrome [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2010 Introduction. Glucagonomas are rare, frequently malignant tumours, arising from the Langerhans' islets of the pancreas. They usually secrete large amounts of glucagon that can cause a characteristic 'glucagonoma syndrome', which includes necrolytic ...
Čolović Radoje +4 more
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