Results 131 to 140 of about 414,407 (362)
, 2019 Glucocorticoid replacement therapy, available since the 1950s, has prolonged the survival of patients with adrenal insufficiency. However, adrenal crises, which are life-threatening medical emergencies, still develop in many affected patients.
Falhammar, Henrik +2 more
core +1 more source
Advanced Healthcare Materials, EarlyView.xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello +2 more
wiley +1 more source
Glucocorticoid-induced osteoporosis.
Clinical and experimental rheumatology, 2011 Glucocorticoid-induced osteoporosis is one of the most important side-effects of glucocorticoid use, leading to an increased fracture risk. In this review, recent advances in the understanding of the mechanisms of glucocorticoid-induced osteoporosis are summarised.
Den Uyl, D. +2 more
openaire +8 more sources
The dual role of glucocorticoid regeneration in inflammation at parturition
Frontiers in ImmunologyIntroductionFetal membrane inflammation is an integral event of parturition. However, excessive pro-inflammatory cytokines can impose threats to the fetus. Coincidentally, the fetal membranes express abundant 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1),
Li-Jun Ling +16 more
doaj +1 more source
Advanced Science, EarlyView.Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
Influence of keratolytics on cutaneous pharmacokinetics of glucocorticoids [PDF]
, 2021 Johannes Wohlrab
openalex +1 more source
Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS
Advanced Science, EarlyView.This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu +14 more
wiley +1 more source
Are Glucocorticoids Truly Effective in Improving the Clinical Prognosis of HSV-1 Encephalitis?
Infection and Drug ResistanceShuhua Xie, Wei Sun, Zhaohui Lai, Xianghong Liu Department of Neurology, Ganzhou People’s Hospital, Jiangxi, 341000, People’s Republic of ChinaCorrespondence: Xianghong Liu, Email lxh7176@126.comBackground: Survivors of herpes simplex encephalitis (HSE ...
Xie S, Sun W, Lai Z, Liu X
doaj
Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen
Advanced Science, EarlyView.Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang +12 more
wiley +1 more source
Evaluation of Glucocorticoid Therapy in Asthma Children with Small Airway Obstruction Based on CT Features of Deep Learning [PDF]
, 2021 Wei Zhang, Yang Wang
openalex +1 more source