Results 151 to 160 of about 443,164 (406)

Overcoming steroid resistance in T cell acute lymphoblastic leukemia [PDF]

open access: yes, 2016
In a Perspective, Pieter Van Vlierberghe and Steven Goossens discuss Meijerink and colleagues' findings on steroid resistance in pediatric T cell acute lymphoblastic ...
Goossens, Steven   +1 more
core   +3 more sources

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

open access: yesNature Genetics, 2011
Development, differentiation and response to environmental stimuli are characterized by sequential changes in cellular state initiated by the de novo binding of regulated transcriptional factors to their cognate genomic sites.
S. John   +7 more
semanticscholar   +1 more source

Comprehensive genetic analysis of poorly differentiated gastric cancer in young females

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Although the involvement of female sex hormones in the development of poorly differentiated gastric cancer in young females is controversial, our detailed analysis using RNA‐seq suggested that the female sex hormone, β‐estradiol plays a role in the development of poorly differentiated gastric cancer in young females. Abstract Aim The reasons behind the
Nobuhiro Nakazawa   +9 more
wiley   +1 more source

State of the art in the treatment of systemic vasculitides

open access: yesFrontiers in Immunology, 2014
Anti-neutrophil cytoplasm antibodies (ANCA) are associated with small vessel vasculitides (AASV) affecting the lungs and kidneys. Structured clinical assessment using the Birmingham Vasculitis Activity Score and Vasculitis Damage Index should form the ...
Raashid Ahmed Luqmani
doaj   +1 more source

気管支喘息における気管支肺胞洗浄液中の細胞成分に対する加齢および副腎皮質ホルモンの影響 [PDF]

open access: yes, 2002
Effects of aging and glucocorticoid therapy on bronchoalveolar lavage (BAL) cells, particularly lymphocytes, neutrophils and eosinophils, were examined in 81 patients with asthma. 1.
Ashida, Kozo   +8 more
core   +1 more source

Work Stressors and Asthma in Female and Male US Workers: Findings From the National Health Interview Survey

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Prior work has linked work stressors to asthma. However, research related to gender‐specific associations remains sparse and yielded mixed results. We aimed to address this gap. Methods We drew on cross‐sectional data from the 2015 National Health Interview Survey (individual‐level response rate = 79.7%).
Adrian Loerbroks   +5 more
wiley   +1 more source

LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome [PDF]

open access: yes, 2013
Natural variation for LPS-induced lethal inflammation in mice is useful for identifying new genes that regulate sepsis, which could form the basis for novel therapies for systemic inflammation in humans.
Beaulieu E   +12 more
core   +2 more sources

Adverse Cardiovascular Risk Profile and Increased Diurnal Salivary Cortisol in Girls With Turner Syndrome: An Exploratory Study

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular ...
Lily Jones   +6 more
wiley   +1 more source

NALP3 inflammasome up-regulation and CASP1 cleavage of the glucocorticoid receptor causes glucocorticoid resistance in leukemia cells

open access: yesNature Genetics, 2015
Glucocorticoids are universally used in the treatment of acute lymphoblastic leukemia (ALL), and resistance to glucocorticoids in leukemia cells confers poor prognosis.
S. Paugh   +44 more
semanticscholar   +1 more source

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