Results 161 to 170 of about 443,164 (406)

Urinary excretion profile of prednisolone and prednisone after rectal administration: Significance in antidoping analysis

open access: yesDrug Testing and Analysis, Volume 14, Issue 11-12, Page 2007-2016, November-December 2022., 2022
In this work, excretion profile of prednisone and prednisolone was evaluated in subjects in therapy with glucocorticoids‐based rectal formulations. The absorption rate and the systemic bioavailability of an active principle after rectal administration are strongly influenced by the type of formulations and the physiological conditions of the absorption
Loredana Iannella   +6 more
wiley   +1 more source

Acute Pharmacodynamic Effects of Glucocorticoids [PDF]

open access: bronze, 1965
Mohinder P. Sambhi   +2 more
openalex   +1 more source

Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy. [PDF]

open access: yes, 2020
BackgroundGlobal gene expression levels are known to be highly dependent upon gross demographic features including age, yet identification of age-related genomic indicators has yet to be comprehensively undertaken in a disease and treatment-specific ...
Burchard, Esteban G   +22 more
core   +1 more source

Refining the adriamycin‐induced focal segmental glomerulosclerosis mouse model to improve reproducibility and animal welfare

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study suggested the instability of Adriamycin (ADR) in aqueous solution as the main contributor to large ADR dose variations in literature of the ADR‐induced mouse model of focal segmental glomerulosclerosis (FSGS). We confirmed that freshly prepared ADR solution dosed at 10.5 mg/kg to be optimal in reliably producing FSGS pathology in BALB/c mice
Haochen Jiang   +8 more
wiley   +1 more source

Corrigendum: Relacorilant, a Selective Glucocorticoid Receptor Modulator, Induces Clinical Improvements in Patients With Cushing Syndrome: Results From A Prospective, Open-Label Phase 2 Study

open access: yesFrontiers in Endocrinology, 2022
Rosario Pivonello   +9 more
doaj   +1 more source

Effects of pregnancy on neuron electrophysiology in prefrontal cortex, hippocampus, and basolateral amygdala of mouse brain

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The electrophysiological change in neurons might contribute to the cognitive and emotional changes during pregnancy. Abstract Background Pregnancy affects learning and memory in women. Thus, to investigate the effects of pregnancy, the authors examined the brain electrophysiology of pregnant mice.
Xuefan Bin, Huijuan Luo
wiley   +1 more source

Research Note: Quantifying corticosterone in turkey (Meleagris gallopavo) feathers using ELISA

open access: yesPoultry Science, 2020
The measurement of corticosterone in feathers is an appealing tool for assessing glucocorticoids in wild and domestic bird species. Feather corticosterone measurements can be performed noninvasively and can provide a means for comparing glucocorticoid ...
Emily M. Leishman   +6 more
doaj  

Inhibition of glucocorticoid-induced apoptosis by targeting splice variants of \u3ci\u3eBIM\u3c/i\u3e mRNA with small interfering RNA and short hairpin RNA. [PDF]

open access: yes, 2004
Glucocorticoids (GCs) induce apoptosis in lymphocytes and are effective agents for the treatment of leukemia. The activated glucocorticoid receptor (GR) initiates a transcriptional program leading to caspase activation and cell death, but the critical ...
Abrams, Marc T.   +3 more
core   +1 more source

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