Results 331 to 340 of about 460,157 (392)

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

Med Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang, Yanyun Pang, Peijia Zhu, Zhengdong Zhang, Sen Guo, Zhijian Wei, Wenzhao Wang, Bin Ning   +7 more
wiley   +1 more source

External validation of the polymyalgia rheumatica impact scale: a prospective cohort study. [PDF]

Rheumatol Adv Pract
Moreel L, Doumen M, Betrains A, De Langhe E, Blockmans D, Vanderschueren S.   +5 more
europepmc   +1 more source

Bovine Milk Extracellular Vesicles as a Preventive Treatment for Bone Dysfunction and Metabolic Alterations in Obese Mice Fed a High‐Refined Carbohydrate Diet

Molecular Nutrition &Food Research, EarlyView.
Obesity induction through a high‐refined carbohydrate (HC) diet in BALB/c mice led to increased bone resorption and bone loss in the femur and maxilla. This diet also resulted in increased adiposity, glucose and lipid levels, and insulin resistance. Treatment with bovine milk extracellular vesicles (MEVs) in HC diet‐fed mice demonstrated reduced bone ...
Francine R. F. Silva, Joyce E. Heredia, Onno J. Arntz, Breno R. Barrioni, Mauro M. Teixeira, Tarcília A. Silva, Fons A. J. van de Loo, Soraia Macari, Adaliene V. M. Ferreira, Marina C. Oliveira   +9 more
wiley   +1 more source

Prolonged glucocorticoid use and rheumatoid arthritis-associated cervical spine deformity. [PDF]

Clin Rheumatol
Lebouille-Veldman AB, Huizinga TWJ, Mekary RA, Vleggeert-Lankamp CLA.   +3 more
europepmc   +1 more source

The Alkaloid Caulerpin Exhibits Potent and Selective Anti-Inflammatory Activity Through Interaction with the Glucocorticoid Receptor. [PDF]

Mar Drugs
Dos Santos JSP, Silva DKC, da Silva Oliveira V, Junior SSS, Dos Santos Rodrigues E, de Souza CVC, Martinez ST, Santos-Filho OA, Meira CS, Soares MBP.   +9 more
europepmc   +1 more source

A comprehensive review of IgG4-related pancreatitis: pathogenesis, diagnosis, and therapeutic advances. [PDF]

Front Immunol
Wu S, Qin X, Jin Z, Yang L.
europepmc   +1 more source

Add-On Treatment with Gliclazide for Cancer Patients with Type 2 Diabetes Undergoing Cyclic Glucocorticoid-Containing Chemotherapy. [PDF]

Biomedicines
Lee SE, Park JH, Kim D, Lee HA, Kang YS, Yoon YS, Jeong YJ, Choi HS, Kim KA.   +8 more
europepmc   +1 more source

A Report of 3 Cases of Adrenal Suppression Due to Glucocorticoid Hypersensitivity to Inhaled Corticosteroids. [PDF]

JCEM Case Rep
Ghanny S, Aisenberg JE, Heinemann J, Ten S, Bhangoo A.   +4 more
europepmc   +1 more source

Glucocorticoid receptor and RUNX transcription factors cooperatively drive CD8 T cells dysfunction in human cancer

Ward CJ, Chakraborty S, Shaji SK, Veiga-Villauriz C, Zhao Q, Chen X, Mahata B.   +6 more
europepmc   +1 more source