ABSTRACT S100 calcium‐binding protein A7 (S100A7) has been implicated in psoriasis and other inflammatory diseases. However, the function of S100A7 in oral lichen planus (OLP), a chronic inflammatory disease, remains unclear. OLP was induced in mice by transplanting human OLP lesions into the backs of thymus‐free mice, and an in vitro cell model was ...
Maimaiti Tudi+3 more
wiley +1 more source
Human alpha-herpesvirus 1 (HSV-1) viral replication and reactivation from latency are expedited by the glucocorticoid receptor. [PDF]
Jones C.
europepmc +1 more source
Sciatic Nerve Stimulation Mitigates Depression‐Like Behaviors and Memory Deficits in Stressed Mice
ABSTRACT Stress causes depression and cognitive decline. With limitations in pharmacotherapy, sciatic nerve stimulation (SNS) offers a promising nondrug alternative. This study aimed to explore the therapeutic efficacy of SNS in mitigating stress‐induced depressive behaviors and memory deficits by focusing on astrocytic dysfunction and cellular ...
Chih‐Hao Tien+10 more
wiley +1 more source
Abstract Purpose Bereiter trochleoplasty (TP) is a well‐described procedure to address trochlear dysplasia (TD). Post‐operative joint stiffness with reduced range of motion (ROM) is a common complication usually requiring arthroscopically assisted manipulation (AAM) with the removal of adhesions and scar tissue. Inferior clinical outcomes after TP have
Christian Dippmann+5 more
wiley +1 more source
Physiologic and structural characterization of desisobutyryl-ciclesonide, a selective glucocorticoid receptor modulator in newborn rats. [PDF]
Jaumotte JD+17 more
europepmc +1 more source
Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang+7 more
wiley +1 more source
miR124a-3p inhibitor alleviates AFB1-induced hepatoxicity via targeting chicken glucocorticoid receptor mRNA. [PDF]
Zhao M+5 more
europepmc +1 more source
Glucocorticoids and Airway Smooth Muscle: A Few More Answers, Still More Questions [PDF]
Nayak, Ajay P.
core +1 more source
Glucocorticoid-mediated acetylated regulation of glucocorticoid receptor and Histone3/Histone4 influence glucocorticoid heterogeneity in children patients with primary nephrotic syndrome. [PDF]
Liang YH+5 more
europepmc +1 more source