Results 91 to 100 of about 29,710 (291)

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Early detection of cerebrospinal fluid/serum glucose ratio: A promising value for mortality prognosis in patients with acute bacterial meningitis

Journal of General and Family Medicine
Background/Aims Given that acute bacterial meningitis (ABM), as community‐acquired meningitis, is considered a life‐threatening medical emergency, early diagnosis and immediate onset of antibiotic therapy are of great importance.
Nasrin Khodashenas, Rouzbeh Rajaei Ghafouri, Asghar Jafari Rouhi, Moloud Balafar   +3 more
doaj   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

Probable sepsis‐associated encephalopathy as a component of multiple organ dysfunction syndrome in a cat with pyothorax

Australian Veterinary Journal, EarlyView.
A 2‐year‐old male neutered domestic shorthair cat with bacterial pyothorax was referred to a tertiary hospital for treatment of sepsis. He met criteria for multiple organ dysfunction syndrome and developed new‐onset neurological dysfunction subsequent to the development of sepsis.
CC Chan, CR Sharp, CJ Boyd
wiley   +1 more source

Erroneous glucose recordings while using mutant variant of quinoprotein glucose dehydrogenase glucometer in a child with galactosemia

, 2013
We report a 2-month-old child with galactosemia and falsely high glucose readings with a glucometer using mutant variant of quinoprotein glucose dehydrogenase (MutQ-GDH) chemistry.
Ranjini Srinivasan, K Sushma, Anantharaman Ramakrishnan, Vageesh Ayyar, Vivek Mathew, Ganapathi Bantwal   +5 more
core   +1 more source

SCD2 Alleviates Diabetes‐Associated Cognitive Dysfunction by Improving Microglial Lipid Metabolism

Cell Proliferation, EarlyView.
This study reveals a novel mechanism of microglial metabolic dysfunction in diabetic cognitive impairment. Defective SCD2 disrupts monounsaturated fatty acid (MUFA) metabolism, triggering mitochondrial oxidative phosphorylation dysfunction and leading to abnormal lipid droplet accumulation (marked by PLIN2).
Yang Yang, Juan He, Jing Zheng, Bing Shao, Lixin Shi, Miao Zhang   +5 more
wiley   +1 more source

A glucometer-based strategy for sensitive DNA methyltransferase activity detection via a polymerization nicking reaction and enzyme amplification

, 2017
The polymerization nicking reaction (PNR) and invertase enzyme amplify the glucometer signal output to achieve simple and sensitive detection of DNA methyltransferase (MTase) activity.
Hongchao Yi, Ying Chen
core   +1 more source

Does faster aspart improve time in range in children with type 1 diabetes with glycaemia close to target on insulin pump therapy?

Diabetic Medicine, EarlyView.
Abstract Aims To evaluate whether faster insulin aspart (FIA) improves time in range (TIR) compared with standard insulin aspart (SIA) in children and adolescents with type 1 diabetes achieving glycaemia close to target treated with continuous subcutaneous insulin infusion (CSII) and continuous glucose monitoring (CGM).
Kowalczyk‐Korcz Emilia, Dymińska Magdalena, Groele Lidia, Szypowska Agnieszka   +3 more
wiley   +1 more source

Detecting Glucose in the Phloem to Quickly Define Latent Post-Fire Mortality in Pinus Trees in Northern Italy

Fire
Background. Wildfires may cause serious injuries to the anatomical structure of trees that can lead to tree death or long-lasting injury recovery, limiting their growth and vitality for several years.
Niccolò Frassinelli, Claudia Cocozza, Enrico Marchi, Cristiano Foderi, Eleftherios Touloupakis, Francesco Neri, Maria Laura Traversi, Alessio Giovannelli   +7 more
doaj   +1 more source

Determination of the Precision of Glucometers Used in Saudi Arabia. [PDF]

Sensors (Basel)
Background: Efforts have been joined to set the parameters for the reliability of glucometers, yet once they are on the market, they are not further tested for the maintenance of accuracy, specificity, or precision. Methods: This comparative analytical study investigated the precision of commonly used glucometers in Saudi Arabia, namely Accu-Chek ...
Al-Othman SA, Al-Zaidany ZH, Al-Ghannam SH, Al-Turki AM, Al-Abdulazeem AA, Vatte C, Habara A, Al-Ali AK, Al-Awami MF.   +8 more
europepmc   +5 more sources