Results 91 to 100 of about 74,459 (251)
Gluconeogenesis: An ancient biochemical pathway with a new twist
Fly, 2017 Synthesis of sugars from simple carbon sources is critical for survival of animals under limited nutrient availability. Thus, sugar-synthesizing enzymes should be present across the entire metazoan spectrum.
Tetsuya Miyamoto, Hubert Amrein
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Nonenzymatic Carboxylate Phosphorylation in Water
European Journal of Organic Chemistry, EarlyView.The phosphorylation of carboxylic acids to acyl phosphates is a recurring reaction in the core of microbial metabolism, a set of processes thought to date back to the origins of life. This study shows that carboxylate phosphorylation occurs in water without enzymes or adenosine triphosphate (ATP), enabled by diamidophosphate and nitrite.
Weiqiang Chen +3 more
wiley +1 more source
Food Frontiers, EarlyView.This study complements the pathogenesis of depression, and the effects of APS from the perspective of “gut microbiome ‐ immunity ‐ metabolome” axis. This study also provides a novel research strategy and approaches for demonstrating the anti‐depression effects of plant polysaccharides, and lays a solid foundation for discovering new medicines from ...
Xiaojie Liu +9 more
wiley +1 more source
Organ‐on‐Chip: The Future of Nutrition Research in a One Health World
Food Frontiers, EarlyView.Organ‐on‐chips offer a promising tool for evaluating food and feed safety. Organ‐on‐chips also present a scientifically robust and ethical alternative to animal studies. ABSTRACT The One Health approach emphasizes the interconnectedness of human, animal, and environmental health, recognizing that the health of each is interdependent and influenced by ...
Manuela Cassotta +8 more
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Experimental Dermatology, Volume 31, Issue 12, Page 1872-1880, December 2022., 2022 Abstract Altered gut microbiota composition has been observed in individuals with hidradenitis suppurutiva (HS) and many other inflammatory diseases, including obesity, type 1 and type 2 diabetes. Here, we addressed whether adalimumab, a systemic anti‐inflammatory therapy, may impact the microbiota biochemical profile, particularly on beneficial ...
Artiene Tatian +7 more
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Mechanisms of transcriptional control of glucose metabolism in hepatocytes
Сахарный диабет, 2016 The hepatic tissue plays a key role in the regulation and maintenance of stable blood glucose levels. The liver is the main gluconeogenesis organ of the body and is under constant hormonal control to determine the metabolic activity of hepatocytes ...
Konstantin Y. Kulebyakin +3 more
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An investigation into the transcription factors and regulatory mechanisms of Aspergillus
Food Safety and Health, EarlyView.Foodborne pathogen Aspergillus, a prevalent etiologic agent among filamentous fungi, are distinguished by a significant repertoire of transcription factors encoded within their genomes. These regulatory proteins are instrumental in orchestrating key biological processes, including cellular growth, secondary metabolite biosynthesis, mycotoxin production,
Yuxin Qin, Huawei Yu, Jun Tian
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Liver-L-alanine-glyoxylate and L-serine-pyruvate aminotransferase activities: an apparent association with gluconeogenesis [PDF]
, 1969 E V Rowsell +3 more
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Exploring the Molecular Pathways Underlying the Anti‐Diabetic Effects of Millets
Food Safety and Health, EarlyView.Millet consumption may modulate gluconeogenesis and glycolysis, enhance glucose transporter activity, increase leptin levels, inhibit the NF‐κB pathway, and mitigate oxidative and nitrosative stress. ABSTRACT Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemic conditions resulting from inadequate insulin production or ...
Akash Kumar +5 more
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Control of glycolysis and gluconeogenesis in rat kidney cortex slices [PDF]
, 1967 A. H. Underwood, E. A. Newsholme
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