Results 91 to 100 of about 134,956 (333)

Intermediary metabolism [PDF]

, 2009
Caenorhabditis elegans has orthologs for most of the key enzymes involved in eukaryotic intermediary metabolism, suggesting that the major metabolic pathways are probably present in this species.
Braeckman, Bart, Houthoofd, Koen, Vanfleteren, Jacques   +2 more
core   +2 more sources

Synthesis, Characterization, Biological Properties, and Sensor Applications of Novel Thiosemicarbazone Derivatives

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen, Oguz Özbek, Meryem Topal, Hatice Şahin, Ümit M. Koçyiğit   +4 more
wiley   +1 more source

The effect of aerobic exercise on the function of the local renin-angiotensin system and gluconeogenesis pathway in the liver tissue of type 2 diabetic rats

Fiyz̤, 2023
Background and Aim: One of the important and effective physiological systems in the pathogenesis of type 2 diabetes is the local renin-angiotensin system. The aim of the current study was to determine the effect of aerobic exercise on the function of the
Mohadeseh Shojaei, Fatemeh Kazeminasab, Mohammadjavad Pourvaghar   +2 more
doaj  

Starvation of Cancer via Induced Ketogenesis and Severe Hypoglycemia

, 2014
Neoplasms are highly dependent on glucose as their substrate for energy production and are generally not able to catabolize other fuel sources such as ketones and fatty acids.
Kapelner, Adam, Vorsanger, Matthew
core   +1 more source

Metabolomics application in maternal-fetal medicine [PDF]

, 2013
Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant
Atzori, L, Fanos, V, Ferrazzi, E, Makarenko, K, Melis, GB   +4 more
core   +4 more sources

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source

Storage oil hydrolysis during early seedling growth [PDF]

, 2009
Storage oil breakdown plays an important role in the life cycle of many plants by providing the carbon skeletons that support seedling growth immediately following germination.
Andrews, Anne-Laure Quettier, Athenstaedt, Athenstaedt, Baker, Beisson, Chia, Ducharme, Eastmond, Eastmond, Eastmond, El-Kouhen, Fernandez, Frandsen, Fuchs, Fuchs, Ghosh, Ghosh, Graham, Grönke, Gupta, Hayashi, Hellyer, Hills, Hills, Hills, Huang, Ishiguro, Jennens, Jolivet, Kurat, Lass, Lin, Lin, Maeshima, Matsui, May, Mhaske, Mukherjee, Murphy, Murphy, Ncube, Noll, Ohlrogge, Ollis, Peter J. Eastmond, Poxleitner, Quettier, Robenek, Rydel, Schweiger, Siloto, Somerville, Stahl, Ubersax, Wanner, Zimmermann   +56 more
core   +1 more source

Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma

Cancer Communications, EarlyView.
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu, Yixiao Xiong, Yuxin Zhang, Huifang Liang, Kun Cheng, Yuanxiang Lu, Guangzhen Cai, Yang Wu, Yunhui Fan, Xiaoping Chen, Hong Zhu, Zeyang Ding, Wanguang Zhang   +12 more
wiley   +1 more source

Metabolic switch from glycogen to lipid in the liver maintains glucose homeostasis in neonatal mice

Journal of Lipid Research, 2023
Neonates strive to acquire energy when the continuous transplacental nutrient supply ceases at birth, whereas milk consumption takes hours to start.
Liangkui Li, Haoyu Zhou, Jinhui Wang, Jiaxin Li, Xuchao Lyu, Wenshan Wang, Chengting Luo, He Huang, Dawang Zhou, Xiaowei Chen, Li Xu, Peng Li   +11 more
doaj  

Lack of Aquaporin 3 in bovine erythrocyte membranes correlates with low glycerol permeation [PDF]

, 2011
NOTICE: this is the author’s version of a work that was accepted for publication in Biochemical and Biophysical Research Communications. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and ...
Abel Oliva, Barker, Bietz, Bradford, Denker, Dix, Elisa Campos, Farmer, Florin-Christensen, Fotiadis, Graça Soveral, Hanahan, Ikeda, Ishibashi, Kuriyama, Laemmli, Liu, Liu, Macey, Macey, Macey, Mazur, Moura, Murata, Paganelli, Paula Leandro, Preston, Roudier, Roudier, Schulte, Scott, Sidel, Simmons, Takata, Teresa F. Moura, van Heeswijk, Zardoya, Zimin, Zou   +38 more
core   +1 more source