Results 221 to 230 of about 171,466 (287)
Metabolic map of Brucellosis: From acute and chronic phase adaptation to targeted nanodrug design. [PDF]
Yu L, Wen M, Ding H.
europepmc +1 more source
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang +10 more
wiley +1 more source
NAC1 Regulates PCK2 Expression and Activates Truncated Gluconeogenesis for Growth Advantage in Ovarian Cancer Cells. [PDF]
Nakayama N +4 more
europepmc +1 more source
In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou +17 more
wiley +1 more source
Metformin-Associated Lactic Acidosis Following Acute Overdose: Clinical Course and Conservative Management. [PDF]
Yadav A +4 more
europepmc +1 more source
Author response: HNF4α-TET2-FBP1 axis contributes to gluconeogenesis and type 2 diabetes
Hongchen Li +11 more
openalex +1 more source
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen +17 more
wiley +1 more source
Dysregulation of cellular metabolism within the gut-brain axis is associated with behavioural changes in chronic intestinal inflammation. [PDF]
Devereaux J +8 more
europepmc +1 more source

