Results 241 to 250 of about 74,459 (251)

NMR‐based metabolomics combined with metabolic pathway analysis reveals metabolic heterogeneity of colorectal cancer tissue at different anatomical locations and stages

International Journal of Cancer, Volume 156, Issue 8, Page 1644-1655, 15 April 2025.
What's new? Current screening tests for colorectal cancer (CRC) include colonoscopy and fecal occult blood test, both of which have significant drawbacks. Here, the authors tested NMR‐based metabolomic fingerprinting as a potential CRC screening technique.
Rongzhi Cai, LiXin Ke, Yan Zhao, Jiayun Zhao, Huanian Zhang, Peie Zheng, Lijing Xin, Changchun Ma, Yan Lin   +8 more
wiley   +1 more source

Circadian clock disruption promotes retinal photoreceptor degeneration

The FASEB Journal, Volume 39, Issue 7, 15 April 2025.
Mice carrying a knock‐in of the P23H mutation of the rhodopsin gene are a well‐characterized model of retinitis pigmentosa (RP), a hereditary retinal degeneration affecting primarily rods. Here, by combining the P23H Rho mutation with the rod‐specific invalidation of the Bmal1 clock gene and by performing functional, structural, and molecular analyses,
Shumet T. Gegnaw, Cristina Sandu, Amandine Bery, Jacoline B. ten Brink, Nemanja Milićević, Aldo Jongejan, Perry D. Moerland, Arthur A. Bergen, Marie‐Paule Felder‐Schmittbuhl   +8 more
wiley   +1 more source

A Gluconeogenesis-Related Genes Model for Predicting Prognosis, Tumor Microenvironment Infiltration, and Drug Sensitivity in Hepatocellular Carcinoma. [PDF]

J Hepatocell Carcinoma
Tang X, Xue J, Zhang J, Zhou J.
europepmc   +1 more source

Current Understanding of Pathogenic Mechanisms and Disease Models of Citrin Deficiency. [PDF]

J Inherit Metab Dis
Lacabanne D, Sowton AP, Jose B, Kunji ERS, Tavoulari S.   +4 more
europepmc   +1 more source

Reprogramming yeast metabolism for customized starch-rich micro-grain through low-carbon microbial manufacturing. [PDF]

Nat Commun
Shi Z, Xu Z, Rong W, Sun H, Zhou H, Yuan Q, Xiao A, Ma H, Cai T, Wang G, Ma Y.   +10 more
europepmc   +1 more source

Transcriptome Analysis of Environmental Adaptation of Largemouth Bass (<i>Micropterus salmonides</i>). [PDF]

Genes (Basel)
Wang Y, Li H, Li C, Tang W, Wang Y, Hou H.   +5 more
europepmc   +1 more source

Tomatine Improves Glucose Metabolism and Mitochondrial Respiration in Insulin-Resistant Hepatocyte Cell Lines AML12 and HepG2 via an AMP-Activated Protein Kinase-Dependent Pathway. [PDF]

Cells
Lee YG, Kim D.
europepmc   +1 more source

Transcriptome and Weighted Gene Co-Expression Network Analysis to Characterize the Expression of Genes Related to Yield Traits in Yunnan Hulled Wheat. [PDF]

Int J Mol Sci
Wang Q, Zhang C, Guo Y, Liu J, Zhang P, Jiang G, Qin P.   +6 more
europepmc   +1 more source