Evidence for a CO2‐concentrating mechanism in the model streptophyte green alga Chara braunii
Summary Oxygenic photosynthesis in streptophytic algae, such as Charophyceae, is often impeded by low CO2 levels in aquatic habitats. Consequently, many algal groups evolved a CO2‐concentrating mechanism (CCM). However, its presence in Charophyceae remains controversial.
Carolin M. Heise+6 more
wiley +1 more source
Integration of transcriptomics and metabolomics data revealed role of insulin resistant SNW1 gene in the pathophysiology of gestational diabetes. [PDF]
Bhushan R+9 more
europepmc +1 more source
Vasopressin‐Sensitive Aqp2 Regulation Mediated by the TAZ‐NR4A1 Axis in Renal Collecting Duct Cells
The TAZ‐NR4A1 axis was identified as a critical regulator of vasopressin‐induced AQP2 expression, essential for water homeostasis. Conditional TAZ‐knockout mice showed polyuria and a significant decrease in AQP2 expression in collecting ducts. In mpkCCDc11 cells, TAZ knockdown significantly impaired vasopressin‐mediated AQP2 expression independently of
Hong Seok Choi+6 more
wiley +1 more source
Ubiquitous expression of an activating mutation in the Pik3ca gene reprograms glucose and lipid metabolism in mice. [PDF]
Caiazzo S+7 more
europepmc +1 more source
ROLE OF DIALYSATE GLUCOSE IN PREVENTING GLUCONEOGENESIS DURING HEMODIALYSIS
Ronald L. Wathen+4 more
openalex +1 more source
This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu+16 more
wiley +1 more source
N‐Lactoyl Amino Acids: Emerging Biomarkers in Metabolism and Disease
ABSTRACT N‐lactoyl amino acids (Lac‐AA) form an emerging class of metabolites that have gained significant attention in recent years due to their ubiquitous presence in different biological systems and potential roles in various biochemical processes. This narrative review aims to provide a comprehensive overview of the current understanding of Lac‐AA,
Khaled Naja+4 more
wiley +1 more source
Tanshinone I improves renal fibrosis by promoting gluconeogenesis through upregulation of peroxisome proliferator-activated receptor-γ coactivator 1α. [PDF]
Bai Y+7 more
europepmc +1 more source