Abstract Blackberry (Rubus ulmifolius Schott) and mugwort (Artemisia campestris L.) are plants traditionally used to treat various pathologies, including hypertension. The vasodilatory and hypotensive effects of blackberry were investigated through experiments in rat models (n = 5 rats per group) and compared with those of mugwort, which had been ...
Afaf Mehiou+8 more
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Lipid Hormones at the Intersection of Metabolic Imbalances and Endocrine Disorders. [PDF]
Dobre MZ+2 more
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The multifaceted roles of ketones in physiology
Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili+3 more
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Adipose Tissue-Derived Extracellular Vesicles Loaded with miR-141-3p Regulate Obesity-Induced Insulin Resistance by Targeting Glycogen Synthesis and Gluconeogenesis. [PDF]
Wang Z+9 more
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Oxyntomodulin physiology and its therapeutic development in obesity and associated complications
Abstract figure legend Physiological influences of OXM and its emerging insights from evidence on bariatric surgery effects. CCK, cholecystokinin; FGF21, fibroblast growth factor 21; GLUT4, glucose transporter type 4; IRS1, insulin receptor substrate‐1; NNMT, nicotinamide N‐methyltransferase; OXM, oxyntomodulin Abstract Incretins, such as glucagon‐like
Martin T. W. Kueh+3 more
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METTL14-Induced M<sup>6</sup>A Methylation Increases G6pc Biosynthesis, Hepatic Glucose Production and Metabolic Disorders in Obesity. [PDF]
Zheng Q+6 more
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Abstract Introduction Metabolic dysfunction‐associated fatty liver disease (MAFLD) is common. This evidence‐based consensus statement summary provides recommendations for the assessment and monitoring of adults with MAFLD in primary care. Main recommendations Adults with type 2 diabetes, obesity or two or more other metabolic risk factors should be ...
Leon A Adams+15 more
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A human cytotrophoblast-villous endothelium-fetal organ multi-cell model and the impact on gene and protein expression in placenta cytotrophoblast, fetal hepatocytes and fetal kidney epithelial cells. [PDF]
Jones HN, Williams A, Wilson RL.
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Abstract Cancer is a complex and heterogeneous disease characterized by various genetic and epigenetic alterations. Early diagnosis, accurate subtyping, and staging are essential for effective, personalized treatment and improved survival rates. Traditional diagnostic methods, such as biopsies, are invasive and carry operational risks that hinder ...
Ezgi Tanıl, Emrah Nikerel
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