Results 51 to 60 of about 162,740 (383)
Cells, 2023 Nanomaterials offer a broad spectrum of applications in biomedicine. The shapes of gold nanoparticles could modulate tumor cell behavior. Spherical (AuNPsp), stars (AuNPst) and rods (AuNPr) shapes of polyethylene glycol coated-gold nanoparticles (AuNPs ...
Sílvia Soares +7 more
doaj +1 more source
Gut microbiota markers in obese adolescent and adult patients: Age-dependent differential patterns [PDF]
, 2018 Obesity levels, especially in children, have dramatically increased over the last few decades. Recently, several studies highlighted the involvement of gut microbiota in the pathophysiology of obesity. We investigated the composition of gut microbiota in
Alessandra Russo +15 more
core +2 more sources
Molecular MetabolismBackground: As the primary source of glucose during fasting, hepatic gluconeogenesis is rigorously regulated to maintain euglycemia. Abnormal gluconeogenesis in the liver can lead to hyperglycemia, a key diagnostic marker and the primary pathological ...
Xiaomin Luo +9 more
doaj +1 more source
Optimized 3D Culture of Hepatic Cells for Liver Organoid Metabolic Assays
Cells, 2021 The liver is among the principal organs for glucose homeostasis and metabolism. Studies of liver metabolism are limited by the inability to expand primary hepatocytes in vitro while maintaining their metabolic functions.
Christian Moya Gamboa +5 more
doaj +1 more source
Metabolomics application in maternal-fetal medicine [PDF]
, 2013 Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant
Atzori, L +4 more
core +4 more sources
Gluconeogenesis in the eel. II. Gluconeogenesis in the alloxanized eel.
NIPPON SUISAN GAKKAISHI, 1975 Gluconeogenesis in eel with alloxan induced insulin deficiency was studied. A single injection of alloxan produced a marked hyperglycemia, glycosuria, and pronounced elevation of plasma amino nitrogen in eel, Liver glycogen decreased 3 days after the alloxan injection but increased after 10 days. There were, however, no appreciable changes in GOT, GPT,
Yasuo Inui, Motoyoshi Yokote
openaire +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
The bloodstream form of Trypanosoma brucei displays non-canonical gluconeogenesis.
PLoS Neglected Tropical DiseasesTrypanosoma brucei is a causative agent of the Human and Animal African Trypanosomiases. The mammalian stage parasites infect various tissues and organs including the bloodstream, central nervous system, skin, adipose tissue and lungs.
Julie Kovářová +4 more
doaj +1 more source
Veterinary Research, 2020 Brucella ovis is a non-zoonotic rough Brucella that causes genital lesions, abortions and increased perinatal mortality in sheep and is responsible for important economic losses worldwide. Research on virulence factors of B.
Nieves Vizcaíno +5 more
doaj +1 more source
Diatom Proteomics Reveals Unique Acclimation Strategies to Mitigate Fe Limitation [PDF]
, 2015 Phytoplankton growth rates are limited by the supply of iron (Fe) in approximately one third of the open ocean, with major implications for carbon dioxide sequestration and carbon (C) biogeochemistry.
Boyd, Philip W. +7 more
core +1 more source