Results 111 to 120 of about 88,788 (276)

Review of Congenital Myasthenic Syndrome Caused by Pathogenic Variants in GFPT1

Muscle &Nerve, EarlyView.
ABSTRACT Glutamine:fructose‐6‐phosphate transaminase 1 (GFPT1) catalyzes the first and rate‐limiting step of the hexosamine biosynthetic pathway (HBP) to generate UDP‐GlcNAc. GFPT1 exon 9 is specifically spliced in in striated muscles, which makes a long isoform of GFPT1 (GFPT1‐L).
Kinji Ohno, Mohammad Nazim, Ruchen Zhang, Paniz Farshadyeganeh, Mikako Ito, Bisei Ohkawara   +5 more
wiley   +1 more source

Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran, Zaharadeen Jimoh, Tariq Issa, Nahla A. Gomaa   +3 more
wiley   +1 more source

Isolation of glucosamine HCl from Penaeus monodon

, 2018
Glucosamine is a compound of amino sugar that is found widely in the cartilage and has a very important role for health and joint flexibility. Glucosamine is generally produced by the hydrolysis of the exoskeletons of marine animals, one of the types of ...
Muhammad Nizammul Hayad Bin Yahya
core  

Ibuprofen and its Interaction with Glucosamine [PDF]

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory and antipyretic actions. In addition, ibuprofen is well absorbed from the gastrointestinal tract following oral or rectal administration.
Du, T.
core   +1 more source

Ineffectiveness of immune checkpoint inhibitors in prostate cancer: is it just a question of ‘‐mabs’?

The Journal of Pathology, EarlyView.
Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi, Irene Torresan, Emilio Francesco Giunta, Sara Bleve, Nicole Brighi, Elisa Tassinari, Sofia Zanuccoli, Maria Concetta Cursano, Cristian Lolli   +8 more
wiley   +1 more source

Prospective short-term observational study of glucosamine complex with chondroprotectors effect in adults with diagnosed knee and/or hip osteoarthritis (Translation to Russian)

Consilium Medicum
Background. Osteoarthritis (OA) of the knee and/or hip is a chronic degenerative disease that severely impacts quality of life. Current treatments, such as NSAIDs, provide only symptomatic relief and are associated with significant side effects.
Maija Puce, Anna Medne-Simsone, Klinta Luize Sprudza   +2 more
doaj   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source

Dietary Glucosamine: Effects and Mechanisms in Relation to Production Performance, Eggshell Quality, and Liver Health of Aged Laying Hens

Animals
The aim of this study is to investigate the effects and mechanisms of GS in relation to the production performance, eggshell quality, and liver health of aged laying hens. A total of 144 elderly laying hens were randomly divided into a control group, a 0.
Wenting Gao, Yanan Wang, Ping Gong, Shahid Ali Rajput, Huanbin Wang, Shengqiang Ye, Yu Yang   +6 more
doaj   +1 more source

Research Trends and Mechanistic Insights Into Natural Medicines for Alzheimer's Disease: A Bibliometric Analysis and Narrative Review

Phytotherapy Research, EarlyView.
Research landscape and mechanistic insights into natural medicines for Alzheimer's disease. ABSTRACT Natural medicines have been widely investigated for Alzheimer's disease (AD), but the development of this field and the relationship between bibliometric themes and experimental evidence remain insufficiently characterized.
Maoning Wang, Xiaolian Zhang, Huaxian Yang, Jianhe Zhao, Wentao Wei, Qian Zhao, Wenjia Wang, Yunhui Hu, Jiansong Fang   +8 more
wiley   +1 more source

S as a measure of the overlap between pairs of BPPS pattern residues and the highest DC scoring pairs for the N-acetyltransferase Gna1 bound to both CoA and N-acetyl-D-glucosamine-6-phosphate (GlcNAc-6P) (pdb: 4ag9; 1.76 Å).

, 2019
S as a measure of the overlap between pairs of BPPS pattern residues and the highest DC scoring pairs for the N-acetyltransferase Gna1 bound to both CoA and N-acetyl-D-glucosamine-6-phosphate (GlcNAc-6P) (pdb: 4ag9; 1.76 Å).
Andrew F. Neuwald (9828), Stephen F. Altschul (245577)   +1 more
core   +1 more source