Results 111 to 120 of about 90,302 (256)
The Journal of Dermatology, EarlyView.ABSTRACT Hereditary angioedema (HAE) is a rare, autosomal dominant, life‐threatening disease characterized by recurrent attacks of swelling of the face, upper airway, gastrointestinal tract, limbs, and/or genitalia. Genetic mutations of the SERPING1 gene encoding the C1‐inhibitor (C1‐INH) plasma protein are associated with HAE‐C1INH.
Kumiko Hosono, Miyako Hoshino
wiley +1 more source
, 2015 Inhibitory activity of glucosamine derivatives against angiotensin I converting enzyme (ACE) was investigated. Many N-substituted glucosamine derivatives were synthesized via 1,3,4,6-tetra-O-acetyl-glucosamine hydrochloride.
Ajiro, H +3 more
core
Insulin secretion in glucosamine-induced hyperglycemia in rats
, 1965 The hyperglycemia response produced by the injection of glucosamine in rats has been studied by comparing the effects of equal doses of glucosamine and glucose on blood glucose, circulating insulin, and pancreatic insulin content.
Julio M. Martin, Gunta Bambers
core +1 more source
Integrative Zoology, EarlyView.This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu +5 more
wiley +1 more source
Purification of glucosamine-6-phosphate N-acetylase from sheep brain
, 1962 The presence of the enzyme glucosamine-6-phosphate acetylase which synthesizes N-acetylglucosamine 6-phosphate from glucosamine 6-phosphate and acetyl-coenzyme A has been established in brain. The enzyme has been purified 75-fold from sheep brain.
Pattabiraman, T. N., Bachhawat, B. K.
core +1 more source
Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures
Allergy, EarlyView.This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally +6 more
wiley +1 more source
Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy
Acta Ophthalmologica, EarlyView.Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki +10 more
wiley +1 more source
AnimalsThe aim of this study is to investigate the effects and mechanisms of GS in relation to the production performance, eggshell quality, and liver health of aged laying hens. A total of 144 elderly laying hens were randomly divided into a control group, a 0.
Wenting Gao +6 more
doaj +1 more source
The FEBS Journal, EarlyView.In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras +3 more
wiley +1 more source
, 2019 S as a measure of biological relevance for the N-acetyltransferase Gna1 bound either to coenzyme A (CoA) (pdb: 4ag7; 1.55 Å) or to both CoA and N-acetyl-D-glucosamine-6-phosphate (GlcNAc-6P) (pdb: 4ag9; 1.76 Å).
Andrew F. Neuwald (9828) +1 more
core +1 more source