Results 121 to 130 of about 88,788 (276)

Applications of chitosan derivatives as adjuvants for nanoparticle‐based vaccines: A comprehensive review

Smart Molecules, EarlyView.
This review highlights how chitosan derivatives enhance nanoparticle‐based vaccines through superior stability, mucoadhesion, and immune modulation. By triggering robust mucosal, humoral, and cellular responses, these biocompatible polymers serve as a transformative platform for next‐generation immunotherapeutics and safe and effective vaccine delivery
Sayantani Dasgupta, Susanta Paul, Swarupananda Mukherjee, Nilanjan Sarkar, Arvind Kumar, Amrita Chakraborty, Anannya Bose, Atanu Hazra, Mainak Chakraborty   +8 more
wiley   +1 more source

Molecular Dynamic and Docking Simulation in Exploring a Potential Extracellular Matrix-Based Antibiofilm: Fighting the Resistant Pseudomonas aeruginosa-Candida albicans

Engineered Science
Glycosyltransferase activity of Bgl2, which mediates 1,3 beta-glucan biosynthesis, and phosphomannomutase/phosphoglucomutase (PMM/PGM), which catalyzes the synthesis of precursors for alginate and the O-antigen chain of lipopolysaccharide, are key ...
Rilia Faradini Putri, Muhammad Ikhlas Abdjan, Dewi Santosaningsih, Yatim Lailun Ni'mah, Nikita Putri, Fatiha Khairunnisa, Muji Harsini, Afaf Baktir   +7 more
doaj   +1 more source

Real‐World Safety and Effectiveness of Icatibant in Patients With Hereditary Angioedema (HAE): Post‐Marketing Surveillance in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Hereditary angioedema (HAE) is a rare, autosomal dominant, life‐threatening disease characterized by recurrent attacks of swelling of the face, upper airway, gastrointestinal tract, limbs, and/or genitalia. Genetic mutations of the SERPING1 gene encoding the C1‐inhibitor (C1‐INH) plasma protein are associated with HAE‐C1INH.
Kumiko Hosono, Miyako Hoshino
wiley   +1 more source

Production and Characterization of Glucosamine from Bovine Synovial Fluid. [PDF]

, 2008
Objectives: Glucosamine is a natural aminomonosaccharide, which is a normal constituent of glycosaminoglycans in cartilage matrix and synovial fluid. Glucosamine has a role in the synthesis of cell membrane (building) lining, collagen, osteoid, and bone ...
MMA, El-hadi, MA, Anwar,
core   +1 more source

Analysis of the gut microbiome in sled dogs reveals glucosamine- and activity-related effects on gut microbial composition

Frontiers in Veterinary Science
The composition of the microbiome influences many aspects of physiology and health, and can be altered by environmental factors, including diet and activity.
Dong Wang, Dong Wang, William A. Russel, Kaitlyn M. Macdonald, Valerie M. De Leon, Ahmet Ay, Ahmet Ay, Kenneth D. Belanger   +7 more
doaj   +1 more source

Comparative Molecular Insights into Developmental and Behavioral Toxicity Induced by Octocrylene and Ethylhexyl Salicylate Exposure on Zebrafish

Integrative Zoology, EarlyView.
This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu, Li Sun, Jiao Chen, Jing Wang, Miao Guan, Shixia Xu   +5 more
wiley   +1 more source

Hydrolysis of alpha-D-glucosamine-l-phosphate [PDF]

, 1963
Some information on the hydrolysis mechanism of phosphate esters was obtained by studying the kinetics of ∝-D-Glucosamine-1-phosphate. ∝-D-Glucosamine-1-phosphate was synthesized, an experimental pH-rate profile for the hydrolysis of this phosphate was ...
Pizanis, Michael James
core  

Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures

Allergy, EarlyView.
This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally, Takeshi Yoshida, Shan Gao, Xueya Cai, Donald Y. M. Leung, Lisa A. Beck, Anna De Benedetto   +6 more
wiley   +1 more source

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki, Annamari T. Immonen, Joel T. Rämö, Aino M. Jaakkola, Kari Krootila, Maria Kaukonen, FinnGen, Aarno Palotie, Hannes Lohi, Tero T. Kivelä, Joni A. Turunen   +10 more
wiley   +1 more source

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N‐glycoprotein deglycosylation process in fungal homeostasis

The FEBS Journal, EarlyView.
In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras, Tanim Jabid Hossain, Magnus Karlsson, Georgios Tzelepis   +3 more
wiley   +1 more source