The Pleiotropic Effects of Beneficial Mutations of Adapted Escherichia coli Populations [PDF]
, 2014 Mutations that improve fitness in one environment can often be beneficial, deleterious, or neutral in alternative environments. When a single mutation effects fitness in multiple environments, it is said to be a pleiotropic, which can have important ...
Van Dam, Brian Scott
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Molecular modeling to study dendrimers for biomedical applications [PDF]
, 2014 © 2014 by the authors; licensee MDPI; Basel; Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
Buhleier +15 more
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Scientific Reports, 2015 This study aimed to investigate the effectiveness and safety of glucosamine, chondroitin, the two in combination, or celecoxib in the treatment of knee osteoarthritis (OA).
C. Zeng +9 more
semanticscholar +1 more source
Mechanochemical and Aging‐Based SN2 Method to Access CO2‐Responsive, High‐Amine‐Loading Chitosan
ChemSusChem, EarlyView.We report a green, scalable mechanochemical SN2 method to synthesize CO2‐responsive chitosan with a record‐high amine loading (DS up to 1.67). This one‐pot process functionalizes both amine and alcohol groups using minimal reagents and energy. The resulting biopolymer exhibits reversible pH and osmotic pressure changes upon CO2 exposure, offering a ...
Galen Yang +5 more
wiley +1 more source
The binding of glycosaminoglycans to peptides : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
, 1994 The overall aim this study was to examine the possibility of using immobilised polypeptide chains to fractionate/separate Glycosaminoglycans (GAG's) from mixtures. Initially individual samples of three GAG classes (chondroitin sulphate, dermatan sulphate
Taylor, Grant John
core
Reclamation of Marine Chitinous Materials for Chitosanase Production via Microbial Conversion by Paenibacillus macerans [PDF]
, 2018 [[abstract]]: Chitinous materials from marine byproducts elicit great interest among biotechnologists for their potential biomedical or agricultural applications.
Anh Dzung Nguyen +4 more
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Synthesis of Rare‐Bacterial Sugar Analogs: Thomosamine and Fluorinated Thomosamine
European Journal of Organic Chemistry, EarlyView.We present the synthesis of protected thomosamine (4‐amino‐4,6‐dideoxy‐d‐galactopyranose), 3‐deoxy‐3‐fluoro‐thomosamine, and 2,3‐dideoxy‐2,3‐difluoro‐thomosamine from levoglucosan (1,6‐anhydro‐β‐d‐glucopyranose). Bacterial carbohydrates that include unusual deoxy amino sugars represent interesting targets in drug discovery.
Sam Bahadori +2 more
wiley +1 more source
Glucosamine and Chondroitin for Osteoarthritis
Journal of International Medical Research, 2008 Osteoarthritis (OA) is a common, chronic disease that most frequently affects the knees and is a major cause of disability in the elderly. It is characterized by progressive cartilage loss, accompanied by secondary changes such as osteophyte formation and calcium deposition.
openaire +3 more sources
Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024
ELECTROPHORESIS, EarlyView.ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
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Glucosamine Modulates T Cell Differentiation through Down-regulating N-Linked Glycosylation of CD25*
Journal of Biological Chemistry, 2015 Background: Glucosamine is an amino sugar that has immunoregulatory effects on T cell-mediated diseases. Results: Glucosamine inhibits Th1, Th2, iTreg cells, but promotes Th17 cell development through interference with N-glycosylation of CD25. Conclusion:
Ming-Wei Chien +8 more
semanticscholar +1 more source