Results 151 to 160 of about 72,901 (235)

Garadacimab for the long‐term prophylaxis of hereditary angioedema

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page e1034-e1044, August 2026.
Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün, Regina Treudler, Petra Staubach, Inmaculada Martinez Saguer, Thomas Linhoff, Markus Magerl   +5 more
wiley   +1 more source

Glucose-Modified Viscosity-Responsive Turn-On Fluorescence Molecular Rotors for Wash-Free Live-Cell Imaging. [PDF]

Chembiochem
Kanamori T, Sadai Y, Hida K, Tsuduki T, Nogi C, Asami H, Ogura SI, Yuasa H.   +7 more
europepmc   +1 more source

Garadacimab zur Langzeitprophylaxe bei hereditärem Angioödem

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page 1034-1046, August 2026.
Zusammenfassung Das hereditäre Angioödem (Hereditary angioedema, HAE), eine seltene und belastende Erkrankung, die durch rezidivierende und spontane Gewebeschwellungsattacken gekennzeichnet ist, weist einen hohen ungedeckten therapeutischen Bedarf auf, da Patienten unter aktuellen prophylaktischen Behandlungen eine unzureichende Krankheitskontrolle ...
Emel Aygören‐Pürsün, Regina Treudler, Petra Staubach, Inmaculada Martinez Saguer, Thomas Linhoff, Markus Magerl   +5 more
wiley   +1 more source

Fluorogenic Coupled Assays Reveal Catalytic Properties, Inhibition Constants and Cellular Location of Mucin‐Active Carbohydrate Sulfatases

Angewandte Chemie, Volume 138, Issue 30, 20 July 2026.
We report plate‐based coupled assays to rapidly and quantitatively determine the activity and selectivity of mucin‐active carbohydrate sulfatases. This fluorogenic assay further enables inhibitor identification and allows determination of (sub‐)cellular location. ABSTRACT Sulfated glycans play a central role in human health and influence cell signaling,
Charles W. E. Tomlinson, Madouc D. Bergers, David N. Bolam, Ana S. Luis, Alan Cartmell, Zachary Armstrong   +5 more
wiley   +2 more sources

Dietary nutgrass (Cyperus rotundus) extract–loaded chitosan nanoparticles: Enhance growth performance, boost immune responses, improve antioxidant capacity, and physiological performance in white leg shrimp (Litopenaeus vannamei)

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract Aquaculture has increasingly turned toward plant extracts' usage as functional additives, owing to their rich content of bioactive compounds that enhance growth performance, boost immune responses, and improve antioxidant capacity in cultured species.
Nader N. Hassona, Nauman Khan, Maryam Alenize, Ahmed Tayel, Salma Elhussein, Jia Longwu, Huici Yang, Yun Li, Nusrat Liaqat, Xilin Dai   +9 more
wiley   +1 more source

Colloidal Deacetylation of Chitin Nanocrystals Results in Amorphous and Patchy Chitosan Chains. [PDF]

ACS Nano
Jin T, Heermant S, Mianehrow H, Parton TG, Carone A, Nedielkov R, Ogawa Y, Kozuch J, Vignolini S.   +8 more
europepmc   +1 more source

Chain‐Length Regulation by WzzE Is Necessary for, but Genetically Separable From, Cyclic Enterobacterial Common Antigen Synthesis

Molecular Microbiology, Volume 126, Issue 2, Page 190-207, August 2026.
Here, we demonstrate that polysaccharide chain length regulation plays a distinct role in enabling formation of a cyclic molecule important for the bacterial cell surface. However, this function is necessary, but not sufficient for the cyclic molecule's biosynthesis.
Joseph F. Carr, Yohannes H. Rezenom, Jennifer S. Rudolf, Daniel J. Warzecha, Angela M. Mitchell   +4 more
wiley   +1 more source

RALP1 is essential for schizont maturation and erythrocyte invasion in Plasmodium falciparum. [PDF]

Parasit Vectors
Wu J, Zhang Z, Pang J, Yang W, Ngim C, Li P, Ye J, Tian B, Cheng X, Wang F, Zhang Q, Shang X.   +11 more
europepmc   +1 more source

Riboflavin Salvage Supports Glycolysis in Borrelia burgdorferi Through Flavin‐Dependent NAD+ Regeneration

Molecular Microbiology, Volume 126, Issue 2, Page 208-219, August 2026.
The Lyme disease agent Borrelia burgdorferi has limited metabolic capabilities and depends on salvage of riboflavin via the BB0316‐BB0319 transport system for generation of critical flavin cofactors FMN and FAD. Riboflavin is important for NAD+ regeneration to fuel glycolysis.
Anna M. Schulz, Grace E. Easterling, Aaditya Balasubramaniyan, Mollie W. Jewett   +3 more
wiley   +1 more source

Efficacy of an Oral Chondroprotective Joint Supplement on Stride Length and Gait Symmetry in Aged Geldings with Chronic Lameness. [PDF]

Animals (Basel)
Harbowy RM, Robison CI, Tillman I, Manfredi JM, Nielsen BD.   +4 more
europepmc   +1 more source