Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
The lipopolysaccharide (LPS) of Segatella copri is a structurally unique, immunomodulatory glycoconjugate. Combining mass spectrometry (MS), nuclear magnetic resonance (NMR), and cytometry by time‐of‐flight (CyTOF), we uncover a rough‐type LPS with reduced TLR4 agonism and selective monocyte effects, further highlighting the key role of LPS chemistry ...
Luca De Simone Carone +17 more
wiley +2 more sources
Comparison of pharmacokinetics of glucosamine and synovial fluid levels following administration of glucosamine sulphate or glucosamine hydrochloride [PDF]
To compare the pharmacokinetics of glucosamine and the synovial fluid levels attained following treatment with glucosamine sulphate or glucosamine hydrochloride in a large animal model at clinically relevant doses.Eight adult female horses were used. Crystalline glucosamine sulphate (Dona) or glucosamine hydrochloride was administered at a dose of 20 ...
Pascal Vachon +6 more
openaire +2 more sources
Laser‐Induced Graphene from Waste Almond Shells
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova +9 more
wiley +1 more source
Iron‐Catalyzed Highly Stereospecific Glycosylation with Glycal Epoxides
We report an iron‐catalyzed, highly stereospecific glycosylation method with glycal epoxides, which is effective for a broad range of substrates, including previously challenging, sterically hindered secondary acceptors and glucuronic ester epoxide donors.
Xiao‐Wen Zhang +5 more
wiley +2 more sources
ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing
A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha +4 more
wiley +1 more source
Synthesis and characterization of Fe3O4@SiO2 nanoparticles functionalized with glucosamine as an effective and magnetic adsorbent with recycling capability in removing Ni2+ ions from aqueous solutions [PDF]
Introduction: In the present study, magnetite nanoparticles were synthesized by co-precipitation method with surface coating by silica nanoparticles. Afterwards, these nanoparticles were functionalized with glucosamine molecules.
Mohsen Esmaeilpour +3 more
doaj +1 more source
Thiolated hyaluronic acid (HAMS) synthesized and characterized by NMR, solubility, thiol content, and pKa, is degraded by Staphylococcal hyaluronate lyase but not by mammalian hyaluronidase. Coating polyphosphate–M23 phage endolysin nanoparticles (M23‐PP) with HAMS confers Staphylococcus aureus responsiveness.
Mariana Blanco Massani +11 more
wiley +1 more source
Glucosamine protects against neuronal but not vascular damage in experimental diabetic retinopathy
Objective: Glucosamine, an intermetabolite of the hexosamine biosynthesis pathway (HBP), is a widely used nutritional supplement in osteoarthritis patients, a subset of whom also suffer from diabetes. HBP is activated in diabetic retinopathy (DR).
Rachana Eshwaran +10 more
doaj +1 more source
Formulating Smart All‐in‐One Chitosan Hydrogel for High Performance Wound Dressing
An innovative approach to fabricating a thermosensitive, highly swelling, degradable, and antibacterial hydrogel composed of a chitosan‐g‐NIPAAm/PVA/PVP copolymer, integrated with AgNPs, for use in wound dressing applications. The hydrogel demonstrates enhanced performance, accelerating the wound healing process.
Chia‐Chi Lin +8 more
wiley +1 more source

