Advantages of osteoarthritis combined treatment with symptomatic slow-acting drugs
The effectiveness of combined drugs, consisting of chondroitin and glucosamine (GA) in the treatment of osteoarthritis (OA) is discussed. Due to their high safety and pleiotropic effects, these drugs can be used in patients with OA (primarily with ...
E. V. Zonova
doaj +1 more source
Mucin glycosylation and sulphation in airway epithelial cells is not influenced by cystic fibrosis transmembrane conductance regulator expression [PDF]
Abnormalities in mucus properties and clearance make a major contribution to the pathology of cystic fibrosis (CF). Our aim was to test the hypothesis that the defects in CF mucus are a direct result of mutations in the CF transmembrane conductance ...
Dell, Anne+6 more
core +1 more source
Molecular Fingerprints for a Novel Enzyme Family in
Actinobacteria have long been the main source of antibiotics, secondary metabolites with tightly controlled biosynthesis by environmental and physiological factors.
José A. Manso+4 more
doaj +1 more source
The induction of Maspin expression by a glucosamine-derivative has an antiproliferative activity in prostate cancer cell lines [PDF]
Mammary serine protease inhibitor or Maspin has been characterized as a class II tumor suppressor gene in several cancer types, among them prostate cancer (CaP).
Cocchiola, Rossana+6 more
core +2 more sources
Phylogenomic study of Burkholderia glathei-like organisms, proposal of 13 novel Burkholderia species and emended descriptions of Burkholderia sordidicola, Burkholderia zhejiangensis, and Burkholderia grimmiae [PDF]
Partial gyrB gene sequence analysis of 17 isolates from human and environmental sources revealed 13 clusters of strains and identified them as Burkholderia glathei Glade (BGC) bacteria.
Cooper, Vaughn S+5 more
core +7 more sources
d-Glucosamine is a protective dietary supplement or medicine for osteoarthritis of the knee, a musculoskeletal disease that leads to a significant deterioration in daily activities and quality of life.
Hideya Shintani+2 more
doaj
The objective of this study is to collate and analyse adverse event reports associated with the use of complementary health products (CHP) submitted to the Health Sciences Authority (HSA) of Singapore for the period 2010–2016 to identify various trends ...
Yimin Xu+11 more
doaj +1 more source
Glucosamine Enhances TRAIL-Induced Apoptosis in the Prostate Cancer Cell Line DU145
Background: Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively kills tumor cells in cancer patients. However, patients often develop TRAIL resistance; thus, agents that can sensitize cells to TRAIL therapy would be ...
Chao Sun+3 more
doaj +1 more source
PQx‐Ph, a water‐soluble conjugated polyelectrolyte, enables rapid and selective fluorescence‐based detection of structurally distinct antibiotics via supramolecular assembly modulation. It achieves nanomolar sensitivity under mild conditions and preserves reliable sensing performance across NOM‐rich and biologically relevant water matrices, supporting ...
Hyena Ji+7 more
wiley +1 more source
O -Acetylated sugars in the gas phase: stability, migration, positional isomers and conformation [PDF]
O-acetylations are functional modifications which can be found on different hydroxyl groups of glycans and which contribute to the fine tuning of their biological activity. Localizing the acetyl modifications is notoriously challenging in glycoanalysis, in particular because of their mobility: loss or migration of the acetyl group may occur through the
arxiv +1 more source