Results 51 to 60 of about 72,901 (235)

Nature‐Derived Chitosan Biopolymer: A Promising Candidate for Sustainable Electronics

Advanced Materials Technologies, EarlyView.
In the creation of environmentally friendly devices, nature‐derived chitosan biopolymer is a promising contender for sustainable electronic research. It can be utilized to create more ecologically friendly scalable gadgets and has a variety of uses in different active layers of electronics.
Joshua McDonald, Ali Nawaz, Amandeep Singh, Prashant Sonar   +3 more
wiley   +1 more source

Glucosamine protects against neuronal but not vascular damage in experimental diabetic retinopathy

Molecular Metabolism, 2021
Objective: Glucosamine, an intermetabolite of the hexosamine biosynthesis pathway (HBP), is a widely used nutritional supplement in osteoarthritis patients, a subset of whom also suffer from diabetes. HBP is activated in diabetic retinopathy (DR).
Rachana Eshwaran, Matthias Kolibabka, Gernot Poschet, Gregor Jainta, Di Zhao, Loic Teuma, Katharina Murillo, Hans-Peter Hammes, Martina Schmidt, Thomas Wieland, Yuxi Feng   +10 more
doaj   +1 more source

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

Artra is a model of combination symptom-modifying therapy for osteoarthrosis and intervertebral osteochondrosis

Неврология, нейропсихиатрия, психосоматика, 2012
The paper gives an update on therapy for osteoarthrosis (OA). Symptomatic sustained-release drugs, particularly structural analogues of the cartilage (glucosamine and chondroitin sulfate), that have the weightiest body of evidence is noted to occupy a ...
V V Badokin
doaj   +1 more source

Secondary metabolic profiling of Serratia marcescens NP10 reveals new stephensiolides and glucosamine derivatives with bacterial membrane activity

Scientific Reports, 2023
Secondary metabolic profiling, using UPLC-MSE and molecular networking, revealed the secondary metabolites produced by Serratia marcescens NP10. The NP10 strain co-produced cyclic and open-ring stephensiolides (i.e., fatty acyl chain linked to Thr–Ser ...
Tanya Clements-Decker, Marina Rautenbach, Wilma van Rensburg, Sehaam Khan, Marietjie Stander, Wesaal Khan   +5 more
doaj   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

Advanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang, Juan Yang, Xin Jiang, Zhanghui Zheng, Hongyu Wei, Na Li, Xiangqiang Chu, Weizhi Liu   +7 more
wiley   +1 more source

Design and Engineering of an Artificial Bifunctional N‐Deacetylase/N‐Sulfotransferase for the Biosynthesis of N‐Sulfated Heparosan

Advanced Science, EarlyView.
An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xintong Xi, Ruirui Xu, Daoan Wang, Guobin Yin, Xinjing Wang, Haiqin Chen, Guocheng Du, Jian Chen, Zhen Kang   +8 more
wiley   +1 more source

Determinação espectroscópica multivariada de glucosamina e condroitina em formulações farmacêuticas Multivariate spectroscopic determination of glucosamine and chondroitin in pharmaceutical formulations

Química Nova, 2008
The objective of this study was to develop and validate an analytical method for quantification of glucosamine and chondroitin in pharmaceutical formulations. Multivariate calibration combined with infrared spectrophotometry allowed this analysis.
Paula Rossignoli, Roberto Pontarolo, Cassyano J. Correr, Gilcelia Cordeiro, Patricio Peralta-Zamora   +4 more
doaj   +1 more source

Assessment of In Vitro Nano‐Cytotoxicity Through Fluorescence Microscopy via Neural Network‐Based Live/Dead Cell Classification

Advanced Intelligent Systems, EarlyView.
FluoAI is a two‐stage, label‐free method for quantifying nanomaterial‐induced cytotoxicity from conventional fluorescence microscopy images. Mask R‐CNN segmentation and DenseNet‐121 classification provide rapid live/dead classification matching human accuracy.
Ugur C. Topkiran, Ali Gasimli, Lal Durmaz, Diya Vashani, Himish Paul, Giridhar R. Akkaraju, Anton V. Naumov   +6 more
wiley   +1 more source

Retrospective Study of Reported Adverse Events Due to Complementary Health Products in Singapore From 2010 to 2016

Frontiers in Medicine, 2018
The objective of this study is to collate and analyse adverse event reports associated with the use of complementary health products (CHP) submitted to the Health Sciences Authority (HSA) of Singapore for the period 2010–2016 to identify various trends ...
Yimin Xu, Yimin Xu, Dhavalkumar N. Patel, Suet-Leng P. Ng, Siew-Har Tan, Dorothy Toh, Jalene Poh, Adena Theen Lim, Cheng-Leng Chan, Cheng-Leng Chan, Min-Yong Low, Hwee-Ling Koh   +11 more
doaj   +1 more source