Results 71 to 80 of about 87,074 (298)

Red Blood Cell‐Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell‐Depleted Thrombi, Restoring Severe Bacteremia in Rats

open access: yesAdvanced Science, EarlyView.
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang   +4 more
wiley   +1 more source

Use of Artra and Artra MSM Forte in osteoarthritis of the large joints and lowback pain

open access: yesМедицинский совет, 2019
Knee and hip joint pain is the first and most common symptom that forces a patient to visit the doctor. Osteoarthritis (OA) treatment is aimed «primarily» at managing symptoms of the disease, i.e.
E. P. Sharapova, L. I. Alekseeva
doaj   +1 more source

Glucosamine HCl-based solid dispersions to enhance the biopharmaceutical properties of acyclovir [PDF]

open access: yes, 2019
The objective of the work presented here was to assess the feasibility of using glucosamine HCl as a solid-dispersion (SD) carrier to enhance the biopharmaceutical properties of a BCS class III/IV drug, acyclovir (ACV). The solid-dispersions of acyclovir
Bhagat, Snehal B.   +6 more
core   +1 more source

The n-acetyl phenylalanine glucosamine derivative attenuates the inflammatory/catabolic environment in a chondrocyte-synoviocyte co-culture system [PDF]

open access: yes, 2019
Osteoarthritis (OA), the most prevalent degenerative joint disease, still lacks a true disease-modifying therapy. The involvement of the NF-κB pathway and its upstream activating kinases in OA pathogenesis has been recognized for many years.
Borzi, R. M.   +7 more
core   +1 more source

A review of glucosamine for knee osteoarthritis: why patented crystalline glucosamine sulfate should be differentiated from other glucosamines to maximize clinical outcomes

open access: yesCurrent Medical Research and Opinion, 2016
The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) treatment algorithm for knee osteoarthritis (OA) recommends symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) first line for the medium to long ...
E. Kucharz   +5 more
semanticscholar   +1 more source

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

open access: yesAdvanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen   +9 more
wiley   +1 more source

Glucosamine Enhances TRAIL-Induced Apoptosis in the Prostate Cancer Cell Line DU145

open access: yesMedicines, 2019
Background: Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively kills tumor cells in cancer patients. However, patients often develop TRAIL resistance; thus, agents that can sensitize cells to TRAIL therapy would be ...
Chao Sun   +3 more
doaj   +1 more source

Secondary metabolic profiling of Serratia marcescens NP10 reveals new stephensiolides and glucosamine derivatives with bacterial membrane activity

open access: yesScientific Reports, 2023
Secondary metabolic profiling, using UPLC-MSE and molecular networking, revealed the secondary metabolites produced by Serratia marcescens NP10. The NP10 strain co-produced cyclic and open-ring stephensiolides (i.e., fatty acyl chain linked to Thr–Ser ...
Tanya Clements-Decker   +5 more
doaj   +1 more source

Bio-Inspired Amphiphilic Block-Copolymers Based on Synthetic Glycopolymer and Poly(Amino Acid) as Potential Drug Delivery Systems [PDF]

open access: yes, 2020
In this work, a method to prepare hybrid amphiphilic block copolymers consisting of biocompatible synthetic glycopolymer with non-degradable backbone and biodegradable poly(amino acid) (PAA) was developed.
Dobrodumov, Anatoliy   +10 more
core   +1 more source

Symmetry Breaking in Meniscus Splitting: Effects of Boundary Conditions and Polymeric Membrane Growth

open access: yesAdvanced Science, EarlyView.
Meniscus splitting in the drying of a viscous polymer dispersion is investigated by focusing on nucleation of multiple nuclei with symmetry breaking and asynchronous nucleus formation. Controlled by spatial boundaries, the first nucleus is generated at a position shifted away from the space center and strongly facilitates the asynchronous second ...
Thi Kim Loc Nguyen   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy