Results 81 to 90 of about 76,703 (258)
Journal of Lipid Research, 2009 Glucosamine impairs hepatic apolipoprotein B100 (apoB100) production by inducing endoplasmic reticulum (ER) stress and enhancing cotranslational and posttranslational apoB100 degradation (Qiu, W., R. K. Avramoglu, A. C. Rutledge, J. Tsai, and K.
Wei Qiu +4 more
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Glycosaminoglycans as Polyelectrolytes: Charge, Interactions, and Applications
ChemBioChem, EarlyView.Glycosaminoglycans (GAGs) are linear, anionic biopolymers with their functions tightly linked to their charge. This review approaches GAGs from a polyelectrolyte perspective, shedding light on how the distribution of sulfate groups and, thus, negative charges, governs their interactions with other biomolecules.
Gergo Peter Szekeres +7 more
wiley +1 more source
ChemBioChem, EarlyView.Metal‐dithiocarbamato glycoconjugates based on gold(III), gold(I)‐phosphino, and gold(I)‐carbene scaffolds are here investigated as potential anticancer agents. Contrary to expectations, they induce cell death by acting at the extracellular level rather than targeting overexpressed glucose transporters.
Andrea Pettenuzzo +4 more
wiley +1 more source
A colorimetric method for the determination of glucosamine and chondrosamine [PDF]
, 1933 Leslie Alderman Elson +1 more
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ChemistryEurope, EarlyView.A borrowing hydrogen strategy using an NHC‐Ir(III) catalyst enables selective N‐functionalization of unprotected amino sugars using alcohols as alkylating agents. The use of unprotected substrates avoids extra steps of protection/deprotection, minimizing waste generation.
Aitor Bermejo‐López +7 more
wiley +1 more source
Finding Drug Candidate Hits With A Hundred Samples: Ultralow Data Screening With Active Learning
ChemistryEurope, EarlyView.Ultra‐low‐data hit discovery becomes practical: starting from randomly selected binders, an active‐learning loop selects only 110 molecules from a 100 k library and have a 100% probability of finding 5 or more top‐1% compounds. Noise tests and alternate libraries confirm robustness, enabling single‐researcher campaigns on smaller budgets.
Jacob M. Nielsen +6 more
wiley +1 more source
Chemistry–Methods, EarlyView.It was demonstrated how carbohydrate ring structures can be separated and identified using cyclic ion mobility mass spectrometry, making solid‐, solution‐, and gas‐phase structures comparable. In addition, it was determined which collisional cross‐section prediction or calculation method is the best suited for carbohydrates.
Viktória Goldschmidt Gőz +7 more
wiley +1 more source
A pH‐Responsive Synthetic Receptor for Switchable Binding of Carbohydrates
ChemPlusChem, EarlyView.A diaminocarbazole macrocyclic receptor, designed for disaccharide recognition in water, exhibits distinct binding properties under alkaline versus neutral pH conditions. Carbohydrates are selectively recognized under alkaline conditions, whereas release of the bound guest occurs at physiological pH, effectively behaving as a pH‐switchable carbohydrate
Francesco Milanesi +4 more
wiley +1 more source
Бюллетень сибирской медицины, 2018 Search and synthesis of glucose derivatives for nuclear medicine is of great current interest. Being a promising analogue of glucose, D-glucosamine iodine labeled glucose derivatives can be applied in rheumatoid arthritis radionuclide diagnostics and ...
M. S. Larkina +9 more
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Synthesis of the anhydrides of α-aminoacyl glucosamines [PDF]
, 1913 Charles Weizmann, Arthur Hopwood
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