Results 1 to 10 of about 1,632,729 (269)

Overexpression of SCAP inhibits autophagy and promotes lipid accumulation in vascular smooth muscle cells

Di-san junyi daxue xuebao, 2022
Objective To determine the effect of sterol regulatory element binding proteins cleavage activating protein (SCAP) on foam cell formation in vascular smooth muscle cells (VSMCs). Methods LV-SCAP were constructed with LV-SCAP, and LV-Control group served
RAO Yuhan, LI Danyang, HOU Xiaoli, YAO Yincheng, SU Yu   +4 more
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Clinical Characteristics of Inpatients With New-Onset Diabetes Mellitus in Eastern China: Based on Novel Clustering Analysis

Frontiers in Endocrinology, 2022
IntroductionThis study aimed to explore the novel classification of inpatients with new-onset diabetes in Eastern China by the cluster-based classification method and compare the clinical characteristics among the different subgroups.MethodsA total of ...
Xueke Song, Xueke Song, Yingqi Lv, Yingqi Lv, Nan Huang, Nan Huang, Jinfang Sun, Ting Yang, Ting Yang, Xiaoyuan Wang, Xiaoyuan Wang, Jianan Zhang, Jianan Zhang, Ziwei Zhou, Ziwei Zhou, Huihua Gao, Jie Li, Wei Zhang, Han Yin, Han Yin, Qiong Wei, Qiong Wei, Kun Wang, Ling Li, Ling Li   +24 more
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CCR5 as a prognostic biomarker correlated with immune infiltrates in head and neck squamous cell carcinoma by bioinformatic study

Hereditas, 2022
Background C-C chemokine receptor 5 (CCR5) has recently been recognized as an underlying therapeutic target for various malignancies. However, the association of CCR5 with prognosis in the head and neck squamous cell carcinoma (HNSC) patients and tumor ...
Chunhong Li, Shanlin Chen, Chuanyu Liu, Chune Mo, Weiwei Gong, Jiahua Hu, Min He, Lei Xie, Xianliang Hou, Jianhong Tang, Minglin Ou   +10 more
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The association of soluble cluster of differentiation 36 with metabolic diseases: A potential biomarker and therapeutic target

Pediatric Discovery, 2023
A cluster of differentiation 36 (CD36), also known as fatty acid translocase, plays an important role in developing and progressing metabolic diseases. Soluble CD36 (sCD36), a circulating form of CD36, is identified in human plasma.
Yun Li, Yaxi Chen, Xiong Z. Ruan
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FAM65A as a novel prognostic biomarker in human tumors reveal by a pan-cancer analysis

Discover Oncology, 2021
Background Family with sequence similarity 65 member A (FAM65A), also known as RIPOR1, is differentially expressed between human tumor and non-tumor tissues in kinds of cancers.
Wenken Liang, Chune Mo, Jianfen Wei, Wei Chen, Weiwei Gong, Jianling Shi, Xianliang Hou, Chunhong Li, Yecheng Deng, Minglin Ou   +9 more
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Neonatal overfeeding in mice aggravates the development of methionine and choline-deficient diet-induced steatohepatitis in adulthood

Genes and Diseases, 2019
Overfeeding in early life is associated with obesity and insulin resistance in adulthood. In the present study, a well-characterized mouse model was used to investigate whether neonatal overfeeding increases susceptibility to the development of non ...
Juan Du, Xuemei Cao, Junlin Diao, Qijuan Zhang, Chuan Peng, Jibin Li, Xiaoqiu Xiao   +6 more
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Microarray and bioinformatic analysis reveal the parental genes of m6A modified circRNAs as novel prognostic signatures in colorectal cancer

Frontiers in Oncology, 2022
BackgroundAccumulating evidences have revealed that the abnormal N6-methyladenosine (m6A) modification is closely associated with the occurrence, development, progression and prognosis of cancer.
Wenken Liang, Wenken Liang, Liyuan Deng, Chune Mo, Wei Chen, Yu Sha, Jianling Shi, Xianliang Hou, Yuping Zhang, Min Yang, Minglin Ou   +10 more
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The Fatty Liver Index, the Strongest Risk Factor for Low Testosterone Level

Obesity Facts, 2023
Introduction: The study aimed to determine if hepatic steatosis assessed by fatty liver index (FLI) was an independent risk factor for male low testosterone level and whether the FLI was the strongest risk factor for low testosterone level in two ...
Luna Liu, Man Li, Pengcheng Chen, Yuchen Li, Qianmei Song, Junming Han, Li Fang, Qingbo Guan, Chunxiao Yu   +8 more
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Applications of Machine Learning Models to Predict and Prevent Obesity: A Mini-Review

Frontiers in Nutrition, 2022
Research on obesity and related diseases has received attention from government policymakers; interventions targeting nutrient intake, dietary patterns, and physical activity are deployed globally. An urgent issue now is how can we improve the efficiency
Xiaobei Zhou, Xiaobei Zhou, Lei Chen, Lei Chen, Lei Chen, Hui-Xin Liu, Hui-Xin Liu, Hui-Xin Liu   +7 more
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Short-Term High-Fat Diet Fuels Colitis Progression in Mice Associated With Changes in Blood Metabolome and Intestinal Gene Expression

Frontiers in Nutrition, 2022
Clinical cases and animal experiments show that high-fat (HF) diet is involved in inflammatory bowel disease (IBD), but the specific mechanism is not fully clear.
Zhen-Hua Wu, Zhen-Hua Wu, Zhen-Hua Wu, Jing Yang, Lei Chen, Lei Chen, Lei Chen, Chuang Du, Chuang Du, Chuang Du, Qi Zhang, Shan-Shan Zhao, Shan-Shan Zhao, Shan-Shan Zhao, Xiao-Yu Wang, Xiao-Yu Wang, Xiao-Yu Wang, Jing Yang, Jing Yang, Jing Yang, Yang Liu, Yang Liu, Demin Cai, Jian Du, Hui-Xin Liu, Hui-Xin Liu, Hui-Xin Liu   +26 more
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