Results 121 to 130 of about 67,753 (222)

Comparison of Three In-House Real PCR Assays Targeting Kinetoplast DNA, the Small Subunit Ribosomal RNA Gene and the Glucose-6-Phosphate Isomerase Gene for the Detection of Leishmania spp. in Human Serum. [PDF]

Pathogens, 2021
Tanida K, Balczun C, Hahn A, Veit A, Nickel B, Poppert S, Scheid PL, Hagen RM, Frickmann H, Loderstädt U, Tannich E.   +10 more
europepmc   +1 more source

Clinical characteristics of anti-glucose-6-phosphate isomerase antibody-positive Japanese patients with rheumatoid arthritis [PDF]

, 2005
Taichi Hayashi, Isao Matsumoto, Yoshifumi Muraki, Reiko Takahashi, Yusuke Chino, Daisuke Goto, Satoshi Ito, Akito Tsutsumi, Takayuki Sumida   +8 more
openalex   +1 more source

Lipid‐associated macrophages are more abundant in subcutaneous than visceral adipose tissue in patients with obesity

Obesity, Volume 33, Issue 8, Page 1543-1554, August 2025.
Abstract Objective Because white adipose tissue is infiltrated by several immune cells and their signature in individuals with obesity has not been fully characterized, we wanted to study the most abundant population, which is macrophages, a subtype of myeloid cell. Methods To address this objective, we performed transcriptomic analysis of subcutaneous
Marjorie Reyes‐Farias, Pablo Fernández‐García, Patricia Corrales, Lorena González, David Navarro‐Sanagustín, Andrea Soria‐Gondek, Silvia Pellitero, Jordi Tarascó, Pau Moreno, José M. Balibrea, Laia Gatell, Lauro Sumoy, María Galán, Ester Martínez, Francesc Villarroya, Rubén Cereijo, Laura Herrero, David Sánchez‐Infantes   +17 more
wiley   +1 more source

Mechanisms of brain damage caused by inorganic fluoride using proteomics-based techniques

环境与职业医学
BackgroundChronic excessive exposure to fluoride can cause damage to the central nervous system and a certain degree of learning and memory impairment. However, the associated mechanism is not yet clear and further exploration is needed.
Xiao ZHOU, Wen WAN, Dewen JIANG, Fujun AI, Ling YE, Minghai LIU, Yi ZHANG, Yanjie LIU   +7 more
doaj   +1 more source

An INS‐1 832/13 𝛽‐Cell Proteome Highlights the Rapid Regulation of Fatty Acid Biosynthesis in Glucose‐Stimulated Insulin Secretion

PROTEOMICS, Volume 25, Issue 15, Page 13-26, August 2025.
ABSTRACT Pancreatic beta cells secrete insulin in response to rising glucose levels, a process known as glucose‐stimulated insulin secretion (GSIS). Here, we acquire proteomes of rat pancreatic INS‐1 832/13 beta cells that were short‐term stimulated with 11 different glucose concentrations from 0 to 20 mM, quantifying the response of 3703 proteins ...
Nina Stremmel, Oliver Lemke, Kathrin Textoris‐Taube, Daniela Ludwig, Michael Mülleder, Julia Muenzner, Markus Ralser   +6 more
wiley   +1 more source

A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary

Aging Cell, Volume 24, Issue 8, August 2025.
Explants of human postmenopausal ovarian cortex and medulla were treated with doxorubicin for 24 h followed by culture for up to 10 days in doxorubicin‐free medium. Single nuclei sequencing and proteomics revealed an unbiased signature of ovarian senescence driven by epithelial cells in the cortex and stromal cells in the cortex and medulla ...
Pooja Raj Devrukhkar, Mark A. Watson, Bikem Soygur, Fei Wu, Joanna Bons, Hannah Anvari, Tomiris Atazhanova, Nicolas Martin, Tommy Tran, Kevin Schneider, Jacob P. Rose, Daniel Winer, Elisheva Shanes, Mary Ellen G. Pavone, Judith Campisi, David Furman, Simon Melov, Birgit Schilling, Francesca E. Duncan   +18 more
wiley   +1 more source

A new model of arthritis induced by a glucose-6-phosphate isomerase peptide: immunological requirements and peptide characterisation [PDF]

, 2012
Angela Pizzolla, Frida Laulund, Kajsa Wing, Rikard Holmdahl   +3 more
openalex   +1 more source

Lipocalin‐2 Restores Soluble Guanylyl Cyclase‐Dependent Dilation of the Afferent Arteriole After Renal Transplantation or Ex Vivo Hypoxia/Reoxygenation in Mice

Acta Physiologica, Volume 241, Issue 8, August 2025.
ABSTRACT Aim Dilatory microvascular function is impaired in ischemia/reperfusion injury in the kidney. Nitric oxide independent activators of soluble guanylyl cyclase (sGC) provide renal protection by dilating microvessels and preserving perfusion, but their efficacy declines after severe hypoxia.
Liang Zhao, Minze Xu, Anna Maria Pfefferkorn, Cem Erdogan, Hubert Schwelberger, Pinchao Wang, Pratik Hemant Khedkar, Marc Eigen, Falk‐Bach Lichtenberger, Rusan Catar, En Yin Lai, Felix Aigner, Pontus B. Persson, Igor Maximilian Sauer, Andreas Patzak, Muhammad Imtiaz Ashraf   +15 more
wiley   +1 more source

Engineering Methylotrophic Yeasts as Cell Factories for Chemical Production Using Methanol as a Feedstock

GCB Bioenergy, Volume 17, Issue 8, August 2025.
Methanol, a sustainable and abundant one‐carbon feedstock, can be utilized by natural methylotrophic yeasts to synthesize valuable chemicals. However, methanol‐based manufacturing with these yeasts faces several challenges, including low assimilation efficiency, carbon loss, and methanol toxicity. This review summarizes and discusses recent engineering
Shuxian Wang, Jiayu Fang, Yanping Zhang, Yin Li, Taicheng Zhu   +4 more
wiley   +1 more source

Skimmianine Attenuates Osteoclast Activity by Suppressing ERp57‐Driven Calcium Oscillations/Calcineurin/Nfatc1 Signalling in Postmenopausal Osteoporosis

Journal of Cellular and Molecular Medicine, Volume 29, Issue 15, August 2025.
ABSTRACT Postmenopausal osteoporosis is primarily attributed to the hyperactivation of osteoclast‐induced bone resorption. The differentiation and function of osteoclasts rely on the regulation of calcium oscillations/calcineurin/nuclear factor of activated T cells (Nfat) pathway.
Yongshuang Lv, Xin Zhang, Qizhen Lu, Yi Zhou, Weiyi Wang, Maosheng Yang, Tao Yuan, Yikai Liu, Shui Sun, Ziqing Li   +9 more
wiley   +1 more source