Results 161 to 170 of about 98,446 (260)

Phase Separation Regulates Metabolism, Mitochondria, and Diseases

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Mitochondrion‐related liquid–liquid phase separation. (1) Phase separation mediates the self‐assembly of mitochondrial nucleoids (mt‐nucleoids). (2) Phase segregation mediates the formation of mitochondrial RNA granules (MRGs). (3) Phase separation mediates the formation of mitochondrial degradosomes.
Chuan Gao   +3 more
wiley   +1 more source

The KRN mouse model of inflammatory arthritis [PDF]

open access: yes, 2018
.: In 1996 a new murine model of spontaneous arthritis was described by the group of Benoist and Mathis. Mice transgenic for a T cell receptor recognizing an epitope of bovine RNase and bred onto a NOD background developed severe destructive arthritis ...
Corr, Maripat, Kyburz, Diego
core  

Overexpression of Transketolase Relieves xylA Repression and Enhances Xylose Utilization in Saccharomyces cerevisiae During Mixed Sugar Fermentation

open access: yesGCB Bioenergy, Volume 17, Issue 7, July 2025.
To overcome the bottleneck of inefficient xylose utilization in lignocellulosic bioethanol production, we constructed a recombinant Saccharomyces cerevisiae strain (INVSc‐xylA‐Xltr1p‐TKL1) by overexpressing the transketolase gene TKL1. This engineering strategy significantly enhanced xylose consumption by 33%, upregulated xylose isomerase (xylA ...
Si Xu   +5 more
wiley   +1 more source

Leaf Turgor Loss Does Not Coincide With Cell Plasmolysis in Drought‐Tolerant Chaparral Species

open access: yesPlant, Cell &Environment, Volume 48, Issue 7, Page 5019-5029, July 2025.
ABSTRACT The water potential at which leaf cells lose turgor (ΨTLP) is a useful predictor of whole‐plant drought tolerance and biome wetness. However, many plants can achieve water potential values below ΨTLP and recover, raising questions about the physiological processes that occur below ΨTLP.
Leonie C. Schönbeck   +2 more
wiley   +1 more source

Manual for starch gel electrophoresis: A method for the detection of genetic variation [PDF]

open access: yes, 1987
The procedure to conduct horizontal starch gel electrophoresis on enzymes is described in detail. Areas covered are (I) collection and storage of specimens, (2) preparation of tissues, (3) preparation of a starch gel, (4) application of enzyme extracts ...
Aebersold, Paul B.   +4 more
core  

Deciphering the Regulatory Networks of the Migrasome‐Associated Cell Subpopulation in Heterotopic Ossification via Multi‐Omics Analysis

open access: yesThe FASEB Journal, Volume 39, Issue 12, 30 June 2025.
Mesenchymal lineage cells (MLin) are identified as a pivotal migrasome‐associated subpopulation driving the progression of heterotopic ossification (HO) via migrasome score analysis in single‐cell transcriptomics. HdWGCNA and random forest analysis reveal Ppib and Tagln as key genes, validated by clinical transcriptomic datasets. Integrated multi‐omics
Guanzhi Li   +6 more
wiley   +1 more source

One-pot Enzymatic Synthesis of Deoxy-thymidine-diphosphate (TDP)-2-deoxy-∝-d-glucose Using Phosphomannomutase

open access: yes, 2010
Production of deoxy-thymidine-diphosphate (TDP)-sugars as substrates of glycosyltransferases, has been one of main hurdles for combinatorial antibiotic biosynthesis, which combines sugar moiety with aglycon of various antibiotics. Here, we report the one-
Kang, Young Bok (Abraham)   +10 more
core  

EFP1 is an ER stress-induced glycoprotein which interacts with the pro-apoptotic protein Par-4 [PDF]

open access: yes, 2009
We have isolated the rat ortholog of EFP1 (EF-hand binding protein 1) as a novel interaction partner of the pro-apoptotic protein Par-4 (prostate apoptosis response-4).
Appel, Sarah   +5 more
core   +1 more source

The industrial potential of enzymes from extremely thermophilic bacteria [PDF]

open access: yes, 1981
The thermal regions of the central North Island of New Zealand are some of the most extensive in the world. In addition, they are readily accessible and contain a diversity of ecological habitats, including a large number at 100°C.
Cowan, Don A.   +2 more
core   +1 more source

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