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K-cells and Glucose-Dependent Insulinotropic Polypeptide in Health and Disease

2010
In the 1970s, glucose-dependent insulinotropic polypeptide (GIP, formerly gastric inhibitory polypeptide), a 42-amino acid peptide hormone, was discovered through a search for enterogastrones and subsequently identified as an incretin, or an insulinotropic hormone secreted in response to intraluminal nutrients.
Young Min, Cho, Timothy J, Kieffer
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The structure-function relationship of glucose-dependent insulinotropic polypeptide

2009
Glucose-dependent insulinotropic polypeptide or gastric inhibitory polypeptide (GIP) is a 42 amino acid endocrine gut hormone which exhibits several direct and indirect effects on fat and glucose metabolism. The first known, and most scrutinized, metabolic function of the hormone was the potentiation of insulin release from pancreatic 13-cells in the ...
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Glucose-Dependent Insulinotropic Polypeptide (GIP)

1999
M. Michael Wolfe   +3 more
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Effects of glucose-dependent insulinotropic polypeptide on glucagon

Cardiovascular Endocrinology, 2016
Christensen, Mikkel, Knop, Filip K.
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Glucose-Dependent Insulinotropic Polypeptide (GIP)

2004
Chi-Chuan Tseng, M. Michael Wolfe
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[Clinical significance of glucose-dependent insulinotropic polypeptide (GIP)].

Vnitrni lekarstvi, 1998
Findings on the effects of GIP indicate that its incretory effect on stimulation of insulin secretion under conditions of hyperglycaemia is more important than the formerly known effect of enterogastrone. Numerous experimental trials provide evidence that GIP can participate in the regulation of the postprandial glucose and lipid metabolism and ...
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