Results 1 to 10 of about 74,465 (332)
Cell Metabolism, 2021 Summary Uncertainty exists as to whether the glucose-dependent insulinotropic polypeptide receptor (GIPR) should be activated or inhibited for the treatment of obesity. Gipr was recently demonstrated in hypothalamic feeding centers, but the physiological
Mostafa Bakhti +2 more
exaly +2 more sources
Association between plasma glucose-dependent insulinotropic polypeptide and active adiponectin in normoglycemic women [PDF]
Endocrine ConnectionsBackground/objectives: Glucose-dependent insulinotropic polypeptide (GIP) is secreted by enteroendocrine K cells in response to nutrient ingestion. The aims of this study were: i) to evaluate the cross-sectional associations between plasma GIP change in ...
Isidora Salvatierra +6 more
doaj +2 more sources
Stimulating intestinal GIP release reduces food intake and body weight in mice
Molecular MetabolismObjective: Glucose dependent insulinotropic polypeptide (GIP) is well established as an incretin hormone, boosting glucose-dependent insulin secretion.
Jo E. Lewis +12 more
doaj +2 more sources
Biology of Incretins: GLP-1 and GIP
Gastroenterology, 2007 Laurie L Baggio, Daniel J Drucker
exaly +2 more sources
Cardiovascular Diabetology, 2022 Tirzepatide is the first dual GIP/GLP-1 receptor co-agonist approved for the treatment of type 2 diabetes in the USA, Europe, and the UAE. Tirzepatide is an acylated peptide engineered to activate the GIP and GLP-1 receptors, key mediators of insulin ...
M. Nauck, D. D’Alessio
semanticscholar +1 more source
Clinical Diabetes, 2023 Unexpected drug shortages of the long-acting glucagon-like peptide-1 (GLP-1) receptor agonists dulaglutide and semaglutide and the dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist tirzepatide emerged in late 2022 and have ...
Heather P. Whitley +2 more
semanticscholar +1 more source
Obesity without diabetes: the role of hormonal regulation
Терапевтический архив, 2020 Aim.Obese patients without diabetes present an interesting phenotype to explore protective mechanisms against type 2 diabetes (T2D) development. In our study we looked for specific hormonal features of obese patients without T2D. Materials and methods.
E. A. Shestakova +5 more
doaj +1 more source
Manufacture of Tl targets by electrodeposition for the study of excitation functions of 203Pb [PDF]
EPJ Web of Conferences, 2023 Natural Tl targets were manufactured by electrochemical deposition on a foil gold backing. The electrochemical parameters were defined after several experiments and reverse pulse potential was chosen to avoid the formation of filaments and dendrites ...
Sounalet Thomas +10 more
doaj +1 more source
Extrapancreatic actions of incretin-based therapies on bone in diabetes mellitus [PDF]
, 2015 Diabetes mellitus is correlated with modifications in bone microarchitectural and mechanical strength, leading to increased bone fragility. The incretin hormones, with a classical effect to increase insulin secretion following food ingestion, are now
Mansur, Sity Aishah
core +3 more sources