Gastric inhibitory polypeptide receptor antagonism suppresses intramuscular adipose tissue accumulation and ameliorates sarcopenia [PDF]
Journal of Cachexia, Sarcopenia and Muscle, 2023 Background Intramuscular adipose tissue (IMAT) formation derived from muscle fibro‐adipogenic progenitors (FAPs) has been recognized as a pathological feature of sarcopenia.
Yuya Takahashi +10 more
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Effects of Mind-Regulation Acupuncture Therapy on Serum Ghrelin, Gastric Inhibitory Polypeptide, Leptin, and Insulin Levels in Breast Cancer Survivors with Cancer-Related Fatigue: A Randomized Controlled Trial [PDF]
International Journal of General Medicine, 2023 Jinxia Li,1 Jingjun Xie,2 Xiaoqing Guo,1 Ruiyang Fu,1 Yaling Wang,1 Xinjun Guan1 1Huzhou Hospital of Traditional Chinese Medicine, Affiliated to Zhejiang Chinese Medical University, Huzhou, Zhejiang, 313000, People’s Republic of China; 2The First People ...
Li J, Xie J, Guo X, Fu R, Wang Y, Guan X
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Gastric inhibitory polypeptide/glucose‐dependent insulinotropic polypeptide signaling in adipose tissue [PDF]
Journal of Diabetes Investigation, 2019 GIPR signaling in adipose tissue plays an important role in HFD‐induced insulin resistance and hepatic steatosis in vivo, with no direct effect on fat accumulation, through IL‐6 ...
Shunsuke Yamane, Norio Harada
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Free fatty acid receptors, G protein‐coupled receptor 120 and G protein‐coupled receptor 40, are essential for oil‐induced gastric inhibitory polypeptide secretion [PDF]
Journal of Diabetes Investigation, 2019 Aims/Introduction Incretin hormone glucose‐dependent insulinotropic polypeptide/gastric inhibitory polypeptide (GIP) plays a key role in high‐fat diet‐induced obesity and insulin resistance.
Akiko Sankoda +8 more
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Gastric inhibitory polypeptide (GIP) is selectively decreased in the roux-limb of dietary obese mice after RYGB surgery. [PDF]
PLoS ONE, 2015 Gastric inhibitory polypeptide (GIP, glucose-dependent insulinotropic polypeptide) is expressed by intestinal K cells to regulate glucose-induced insulin secretion. The impact of Roux-en Y bypass (RYGB) surgery on blood GIP is highly contraversial.
Jiaqiang Zhou +4 more
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Association of gastric inhibitory polypeptide receptor (GIPR) gene polymorphism with type 2 diabetes mellitus in iranian patients [PDF]
BMC Medical Genomics, 2023 Introduction Gastric inhibitory polypeptide receptor (GIPR) encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was demonstrated to stimulate insulin secretion. Relation of GIPR gene variation to impaired insulin response
Saiedeh Erfanian +3 more
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Gastric inhibitory polypeptide receptor antagonist, SKL-14959, suppressed body weight gain on diet-induced obesity mice. [PDF]
Obes Sci Pract, 2018 Gastric inhibitory polypeptide plays a role in glucose and lipid metabolism and is associated with obesity and insulin resistance. The objective of this study is to confirm the anti‐obesity effects of the gastric inhibitory polypeptide receptor ...
Nakamura T +6 more
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Mechanisms of fat-induced gastric inhibitory polypeptide/glucose-dependent insulinotropic polypeptide secretion from K cells. [PDF]
J Diabetes Investig, 2016 Gastric inhibitory polypeptide/glucose‐dependent insulinotropic polypeptide (GIP) is one of the incretins, which are gastrointestinal hormones released in response to nutrient ingestion and potentiate glucose‐stimulated insulin secretion.
Yamane S, Harada N, Inagaki N.
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Discovery of gastric inhibitory polypeptide and its subsequent fate: Personal reflections. [PDF]
J Diabetes Investig, 2016 The present review focuses initially on experimental studies that were designed to identify acid inhibitory factors, referred to as ‘enterogastrones,’ that ultimately led to the isolation of gastric inhibitory polypeptide (GIP), a 42‐amino acid ...
Pederson RA, McIntosh CH.
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Investigating the role of melanocortinergic, glutamatergic and neuropeptide Y systems on hypophagia caused by gastric inhibitory polypeptide (GIP) in broilers [PDF]
Poultry Science: Appetite control and the metabolic rate of energy expenditure are under the influence of a broad suite of biochemical messengers, which include peptide-based signals, hormonal agents, and neurotransmitters.
Maryam Lotfi Gharaie +3 more
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