Results 41 to 50 of about 725,921 (266)

Diabetes is predominantly an intestinal disease

Indian Journal of Endocrinology and Metabolism, 2013
Diabetes mellitus (DM) is a chronic, progressive, medically incurable disease and is poorly controlled in a vast majority, in spite of tremendous advancements in pharmacotherapy. Altered gut microbiome can predict diabetes. There is strong and consistent
Debmalya Sanyal
doaj   +1 more source

Chylous Ascites After Gastric Cancer Surgery: Risk Factors and Treatment Results [PDF]

, 2023
Purpose: Although chylous ascites is a frequent complication of radical gastrectomy for gastric cancer, proper diagnostic criteria and optimal treatment strategies have not been established.
박성현, 형우진, 김기윤, 김유민, 김형일, 조민아   +5 more
core   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

The integrated incretin effect is reduced by both glucose intolerance and obesity in Japanese subjects

Frontiers in Endocrinology
IntroductionIncretin-based drugs are extensively utilized in the treatment of type 2 diabetes (T2D), with remarkable clinical efficacy. These drugs were developed based on findings that the incretin effect is reduced in T2D.
Akihiro Hamasaki, Akihiro Hamasaki, Norio Harada, Atsushi Muraoka, Shunsuke Yamane, Erina Joo, Kazuyo Suzuki, Nobuya Inagaki   +7 more
doaj   +1 more source

Identification of Kunitz inhibitor from Cassia obtusifolia L. and its inhibitory effect against Pieris rapae proteases

浙江大学学报. 农业与生命科学版, 2008
A trypsin inhibitor from Cassia obtusifolia seeds, a well known Chinese herb, was isolated to apparent homogeneity by a combination of distilled water extraction, ammonium sulfate precipitation, Sepharose 4B-trypsin affinity and Sephadex G-75 ...
LIAO Hai, REN Wei, ZHAO Xiao-jun, DU Lin-fang   +3 more
doaj   +1 more source

Clinical Implications of Microsatellite Instability in Early Gastric Cancer [PDF]

, 2019
Purpose: We aimed to evaluate the clinical characteristics of microsatellite instability in early gastric cancer. Materials and methods: The microsatellite instability status of resected early gastric tumors was evaluated using two mononucleotide ...
손태일, 서원준, 최윤영, 김현기, 형우진, 김동규, 최서희, 정재호, 노성훈, 김형일, 신수진, 조민아   +11 more
core   +1 more source

New therapeutic options for metabolic‐associated steatotic liver disease

British Journal of Clinical Pharmacology, EarlyView.
An increasing number of patients are being diagnosed with metabolic dysfunction‐associated steatotic liver disease (MASLD). MASLD results from disturbances in hepatic lipid metabolism and is associated with an increased risk of cirrhosis and hepatocellular carcinoma and significant extrahepatic morbidity, including cardiovascular disease and ...
Tessa Straatmijer, Midas Mulder
wiley   +1 more source

Cloning and Tissue Expression of gastric inhibitory polypeptide/glucose-dependent insulinotropic polypeptide (GIP) in Pigs

四川大学学报. 自然科学版, 2017
The gastric inhibitory polypeptide/glucose-dependent insulinotropic polypeptide (GIP) shows the inhibitory effect on gastric acid secretion and incretin action. The aim of this study is to analyze the cDNA sequence of the pig GIP (pGIP) gene, and further
CHENG Shao-Chen, ZHANG Jian-Nan, ZHONG Yu, LI Juan, WANG Ya-Jun   +4 more
doaj  

Emerging concepts in obesity management: focus on glucagon receptor agonist combinations

Drugs in Context
The global rise in obesity and its associated health risks has driven the need for more effective pharmacological treatments. Glucagon receptor (GCGR)-based multi-agonist drugs are emerging as promising treatments for obesity, with several in advanced ...
Sarah L Anderson
doaj   +1 more source

Gastrointestinal motor function and glycaemic control in diabetes. [PDF]

, 2010
This thesis focuses on the role of gastric emptying and gastrointestinal hormones in the regulation of glycaemia and appetite in health and patients with type 2 diabetes.
Ma, Jing
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