Results 31 to 40 of about 64,020 (335)

Novel Molecules Regulating Energy Homeostasis: Physiology and Regulation by Macronutrient Intake and Weight Loss [PDF]

Endocrinology and Metabolism, 2016
Excess energy intake, without a compensatory increase of energy expenditure, leads to obesity. Several molecules are involved in energy homeostasis regulation and new ones are being discovered constantly.
Anna Gavrieli, Christos S. Mantzoros
doaj   +1 more source

General amyloid inhibitors? A critical examination of the inhibition of IAPP amyloid formation by inositol stereoisomers. [PDF]

, 2014
Islet amyloid polypeptide (IAPP or amylin) forms amyloid deposits in the islets of Langerhans; a process that is believed to contribute to the progression of type 2 diabetes and to the failure of islet transplants.
Raleigh, David, Wang, Hui
core   +2 more sources

Blockade of gastric inhibitory polypeptide (GIP) action as a novel means of countering insulin resistance in the treatment of obesity-diabetes.

Peptides, 2019
Gastric inhibitory polypeptide (GIP) is a 42 amino acid hormone secreted from intestinal K-cells in response to nutrient ingestion. Despite a recognised physiological role for GIP as an insulin secretagogue to control postprandial blood glucose levels ...
N. Irwin, V. Gault, F. O’Harte, P. Flatt   +3 more
semanticscholar   +1 more source

Effect of Intraduodenal Bile and Taurodeoxycholate on Exocrine Pancreatic Secretion and on Plasma Levels of Vasoactive Intestinal Polypeptide and Somatostatin in Man [PDF]

, 1994
Intraduodenal (i.d.) application of bile or Na-taurodeoxycholate (TDC) dose dependently enhances basal exocrine pancreatic secretion. The hydrokinetic effect is mediated at least in part by secretin.
Fiedler, Fritz, Lehnert, Peter, Riepl, Rudolf L., Teufel, Johannes   +3 more
core   +1 more source

Effect of Intraduodenal Bile and Na-Taurodeoxycholate on Exocrine Pancreatic Secretion and on Plasma Levels of Secretin, Pancreatic Polypeptide, and Gastrin in Man [PDF]

, 1990
The effect of intraduodenally administered cattle bile (CB) and Na-taurodeoxycholate (TDC) on basal pancreatic secretion and plasma levels of secretin, pancreatic polypeptide (PP), and gastrin were investigated on two separate days in 10 fasting ...
A. Scharl, Aronchick C A, Bjornsson O G, Bondesen S, Burhol P G, Burhol P G, Burhol P G, Carey M C, Davies H A, Dragstedt L R, F. Fiedler, Fahrenkrug J, Flaten O, Florholmen J, Forell M M, Forell M M, Greenberg G R, Gries E, Grossman M I, Hanssen L E, Hartmann W, Hunter W M, I. Hempen, J. Teufel, Jorde R, Konturek S J, Lehnert P, Londong W, Lonovics J, Malagelada J-R., Malagelada J-R., Miyasaka K, Miyazaki K, Moreland H J, Morris B J, Osnes M, Osnes M, Otte M, P. G. Burhol, P. Lehnert, Petersen H, R. L. Riepl, Scatchard G, Schaffalitzky de Muckadell O B, Schwartz T W, Thomas J E, Wormsley K G   +46 more
core   +1 more source

An Immunocytochemical Study of Endocrine Cells in the Gut of a Stomachless Teleost Fish, Grass Carp, Cyprinidae

Cell Transplantation, 1993
Nineteen different antisera raised against mammalian hormones were used to identify the occurrence and distribution of endocrine cells in the gut of grass carp (Ctenopharyngodon idellus).
Qian-Sheng Pan, Zhi-Ping Fang
doaj   +1 more source

Daily consumption of monoglucosyl-rutin prevents high-fat diet-induced obesity by suppressing gastric inhibitory polypeptide secretion in mice

Functional Foods in Health and Disease, 2018
Background: Alpha monoglucosyl-rutin (4G-α-D-glucopyranosyl rutin, αMR) has been shown to stimulate antioxidant defenses and anti-glycation. We evaluated the effects of αMR on body weight gain in mice.Methods: Male C57BL/6J mice were divided into four ...
D. Yokoyama, Wataru Tanaka, Yushi Hashizume, M. Tandia, M. Sakono, K. Shimoi, H. Sakakibara   +6 more
semanticscholar   +1 more source

Dysregulation of Insulin-Linked Metabolic Pathways in Alzheimer’s Disease: Co-Factor Role of Apolipoprotein E 4

Journal of Alzheimer's Disease Reports, 2020
Background: Brain insulin resistance and deficiency are well-recognized abnormalities in Alzheimer’s disease (AD) and likely mediators of impaired energy metabolism.
James Robbins, Oriol Busquets, Ming Tong, Suzanne M. de la Monte   +3 more
doaj   +1 more source

Clinical efficacy and safety of linagliptin in patients with diabetes type 2

Медицинский совет, 2016
Treatment of diabetes mellitus type 2 (T2DM) is a serious challenge which forces to search for new approaches in order to improve the results of pharmacotherapy. Recent advances in diabetology pertain to incretin-directed therapies.
E. V. Biryukova, A. M. Mkrtumyan
doaj   +1 more source

Efficacy and Safety of Tirzepatide in Type 2 Diabetes and Obesity Management

Journal of Obesity & Metabolic Syndrome, 2023
The combination of glucagon-like peptide-1 (GLP-1) with other gut hormones including the glucose-dependent insulinotropic polypeptide (GIP) has been explored to complement and enhance further the GLP-1 effects on glycemia and weight loss.
Rachel Sinha, Dimitris Papamargaritis, Jack A. Sargeant, Melanie J. Davies   +3 more
doaj   +1 more source