Results 11 to 20 of about 21,178 (234)

Investigating the role of melanocortinergic, glutamatergic and neuropeptide Y systems on hypophagia caused by gastric inhibitory polypeptide (GIP) in broilers [PDF]

Poultry Science
: Appetite control and the metabolic rate of energy expenditure are under the influence of a broad suite of biochemical messengers, which include peptide-based signals, hormonal agents, and neurotransmitters.
Maryam Lotfi Gharaie, Morteza Zendehdel, Hamed Zarei, Kimia Mahdavi   +3 more
doaj   +2 more sources

Combined treatment with a gastric inhibitory polypeptide receptor antagonist and a peptidyl peptidase-4 inhibitor improves metabolic abnormalities in diabetic mice [PDF]

Journal of International Medical Research, 2021
Objectives Dipeptidyl peptidase-4 inhibition and gastric inhibitory polypeptide (GIP) receptor antagonism have therapeutic effects in type 2 diabetes mellitus. We assessed the effects of sitagliptin and Pro 3 (GIP) in a mouse model of diabetes.
Fei Yang, Shan Dang, Hongjun LV, Bingyin Shi   +3 more
doaj   +2 more sources

Free fatty acid receptors, G protein‐coupled receptor 120 and G protein‐coupled receptor 40, are essential for oil‐induced gastric inhibitory polypeptide secretion [PDF]

Journal of Diabetes Investigation, 2019
Aims/Introduction Incretin hormone glucose‐dependent insulinotropic polypeptide/gastric inhibitory polypeptide (GIP) plays a key role in high‐fat diet‐induced obesity and insulin resistance.
Akiko Sankoda, Norio Harada, Tomoko Kato, Eri Ikeguchi, Kanako Iwasaki, Shunsuke Yamane, Yuki Murata, Akira Hirasawa, Nobuya Inagaki   +8 more
doaj   +2 more sources

Gastric inhibitory polypeptide receptor methylation in newly diagnosed, drug-naïve patients with type 2 diabetes: a case-control study. [PDF]

PLoS ONE, 2013
GIP action in type 2 diabetic (T2D) patients is altered. We hypothesized that methylation changes could be present in GIP receptor of T2D patients.
Silvia Canivell, Elena G Ruano, Antoni Sisó-Almirall, Belchin Kostov, Luis González-de Paz, Eduardo Fernandez-Rebollo, Felicia Hanzu, Marcelina Párrizas, Anna Novials, Ramon Gomis   +9 more
doaj   +2 more sources

Gastric inhibitory polypeptide/glucose‐dependent insulinotropic polypeptide signaling in adipose tissue [PDF]

Journal of Diabetes Investigation, 2019
Shunsuke Yamane, Norio Harada
doaj   +2 more sources

First Evaluation of Roux-en-Y Gastric Bypass as a Novel Surgical Treatment for Diabetes and Glucose Metabolism Regulation in Cats [PDF]

Veterinary Sciences
Objective: To evaluate the efficacy of Roux-en-Y gastric bypass (RYGB) in improving glucose regulation and metabolic parameters in feline diabetes mellitus (FDM).
Linfeng Li, Guoxiang Yuan, Qianbo Xiong, Wen Hao, Lingchen Yang   +4 more
doaj   +2 more sources

Hormonal predictors of the insulin sensitive phenotype in humans [PDF]

Biomolecules & Biomedicine
Clinical obesity, a chronic condition marked by excessive fat accumulation, often leads to insulin resistance and a heightened risk of comorbidities. This study aimed to identify hormonal predictors of an insulin-sensitive phenotype (ISP) in patients ...
Mohamed Badie Ahmed, Abdella M. Habib, Saif Badran, Abeer Alsherawi, Sherouk Essam Elnefaily, Mansour Binfayed, Atalla Hammouda, Graeme Glass, Ibrahem Abdalhakam, Abdul-Badi Abou-Samra, Suhail A. Doi   +10 more
doaj   +2 more sources

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

Dysregulation of Insulin-Linked Metabolic Pathways in Alzheimer’s Disease: Co-Factor Role of Apolipoprotein E 4

Journal of Alzheimer's Disease Reports, 2020
Background: Brain insulin resistance and deficiency are well-recognized abnormalities in Alzheimer’s disease (AD) and likely mediators of impaired energy metabolism.
James Robbins, Oriol Busquets, Ming Tong, Suzanne M. de la Monte   +3 more
doaj   +1 more source

Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups

BMC Medical Genetics, 2009
Background Gastric inhibitory polypeptide (GIP) is postulated to be involved in type 2 diabetes mellitus and obesity. It exerts its function through its receptor, GIPR.
Rief Winfried, Reinehr Thomas, Völzke Henry, Rosskopf Dieter, Bornhorst Alexa, Grallert Harald, Wang Hai-Jun, Nguyen Thuy T, Brönner Günter, Scherag André, Vogel Carla IG, Illig Thomas, Wichmann H-Erich, Schäfer Helmut, Hebebrand Johannes, Hinney Anke   +15 more
doaj   +1 more source