Results 21 to 30 of about 27,755 (279)

Medial Temporal Lobe Subregional Atrophy in Aging and Alzheimer's Disease: A Longitudinal Study

open access: yesFrontiers in Aging Neuroscience, 2021
Medial temporal lobe (MTL) atrophy is a key feature of Alzheimer's disease (AD), however, it also occurs in typical aging. To enhance the clinical utility of this biomarker, we need to better understand the differential effects of age and AD by ...
Léa Chauveau   +8 more
doaj   +1 more source

An enzymatically stable GIP/xenin hybrid peptide restores GIP sensitivity, enhances beta cell function and improves glucose homeostasis in high-fat-fed mice [PDF]

open access: yes, 2016
AIMS/HYPOTHESIS: Glucose-dependent insulinotropic polypeptide (GIP) and xenin, regulatory gut hormones secreted from enteroendocrine K cells, exert important effects on metabolism. In addition, xenin potentiates the biological actions of GIP. The present
Gault, Victor A   +15 more
core   +1 more source

Potential of using polyethylene as viscosity enhancer of palm oil to use as a lubricating oil

open access: yesAdvances in Mechanical Engineering, 2020
Biodegradable vegetable oil-based lubricating oil is a better auxiliary for mineral-based lubricants as their viscosity index, flash point, lubricity is high.
TKKS Pathmasiri, GIP Perera
doaj   +1 more source

The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection

open access: yesFrontiers in Endocrinology, 2022
The intestinal hormone, glucose-dependent insulinotropic polypeptide (GIP), is involved in important physiological functions, including postprandial blood glucose homeostasis, bone remodeling, and lipid metabolism.
Peter Lindquist   +6 more
doaj   +1 more source

Establishment of novel specific assay for short‐form glucose‐dependent insulinotropic polypeptide and evaluation of its secretion in nondiabetic subjects

open access: yesPhysiological Reports, 2020
The short‐form glucose‐dependent insulinotropic polypeptide (GIP) (1–30) is released from islet alpha cells and promotes insulin secretion in a paracrine manner in vitro. However, it is not well elucidated how GIP (1–30) is involved in glucose metabolism
Yasutaka Takeda   +8 more
doaj   +1 more source

A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control. [PDF]

open access: yesPLoS ONE, 2010
AIMS:The gastrointestinal hormone GIP promotes pancreatic islet function and exerts pro-survival actions on cultured beta-cells. However, GIP also promotes lipogenesis, thus potentially restricting its therapeutic use.
Scott B Widenmaier   +9 more
doaj   +1 more source

Gluten Immunogenic Peptides (GIP) Point-of-Care Urine Test in Coeliac Disease Follow-up before and during the COVID-19 Lockdown in Italy

open access: yesClinical and Experimental Gastroenterology, 2021
Carolina Ciacci,1 Mario Gagliardi,1 Monica Siniscalchi,1 Monica Ruotolo,1 Antonella Santonicola,1 Najla Hajji,1 Fabiana Zingone2 1Celiac Center at Department of Medicine, Surgery, and Dentistry, Scuola Medica Salernitana, University of Salerno, Salerno ...
Ciacci C   +6 more
doaj  

Effects of GLP-1 receptor agonists and dual incretin agonists on adipocyte type and size [PDF]

open access: yesExploration of Endocrine and Metabolic Diseases
Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) and dual incretin agonists have demonstrated significant potential in improving adipose tissue function beyond their established effects on appetite suppression and weight loss.
Nino Turashvili
doaj   +1 more source

Glucose-Dependent Insulinotropic Polypeptide Suppresses Foam Cell Formation of Macrophages through Inhibition of the Cyclin-Dependent Kinase 5-CD36 Pathway

open access: yesBiomedicines, 2021
Glucose-dependent insulinotropic polypeptide (GIP) has been reported to have an atheroprotective property in animal models. However, the effect of GIP on macrophage foam cell formation, a crucial step of atherosclerosis, remains largely unknown.
Michishige Terasaki   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy